CAS 5746-90-7

3-Methylglutaconic acid

Description:

3-Methylglutaconic acid, with the CAS number 5746-90-7, is an organic compound characterized by its carboxylic acid functional groups and a branched-chain structure. It is a derivative of glutaconic acid, featuring a methyl group at the third carbon position. This compound is typically a colorless to pale yellow solid and is soluble in water due to the presence of its carboxylic acid groups. 3-Methylglutaconic acid is of particular interest in biochemical research, as it is associated with certain metabolic disorders, including 3-methylglutaconic aciduria, which can result from defects in mitochondrial function. The compound can participate in various chemical reactions, including esterification and decarboxylation, making it relevant in synthetic organic chemistry. Its molecular formula reflects its composition of carbon, hydrogen, and oxygen, and its structure allows for potential interactions with enzymes and other biological molecules. Overall, 3-methylglutaconic acid serves as an important compound in both clinical and synthetic contexts.

Formula: C₆H₈O₄

InChI: InChI=1S/C6H8O4/c1-4(2-5(7)8)3-6(9)10/h2H,3H2,1H3,(H,7,8)(H,9,10)

InChI key: InChIKey=WKRBKYFIJPGYQC-UHFFFAOYSA-N

SMILES: C(C(=CC(O)=O)C)C(O)=O

Synonyms:

• (2E)-3-Methyl-2-pentenedioic acid
• 2-Pentenedioic acid, 3-methyl-
• 2-pentenedioic acid, 3-methyl-, (2E)-
• 3-Methyl-2-pentenedioic acid
• 3-Methylglutaconic acid
• Glutaconic acid, 3-methyl-
• NSC 249232
• β-Methylglutaconic acid
• (2E)-3-Methylpent-2-enedioic acid

3-Methylglutaconic Acid

CAS: 5746-90-7

Formula: C₆H₈O₄

Purity: >95.0%(GC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 144.13

Ref: 3B-M3764

3-Methylpent-2-enedioic acid

CAS: 5746-90-7

3-Methylpent-2-enedioic acid

Purity: 97%

Molecular weight: 144.1260071

Ref: 10-F870453

3-Methylglutaconic acid

CAS: 5746-90-7

3-Methylglutaconic acid

Purity: ≥95%

Ref: 54-OR1036762

3-Methylpent-2-enedioic acid

CAS: 5746-90-7

Formula: C₆H₈O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 144.1253

Ref: IN-DA00ED5Z

3-Methylglutaconic Acid

Controlled Product

CAS: 5746-90-7

Stability Hygroscopic
Applications 3-Methylglutaconic acid is a glutarate which builds up in the urine in 3-methylglutaconic aciduria. 3-methylglutaconic aciduria is a term used to describe five different disorders that impair the functioning of energy-producing centers within cells (mitochondria)
References Walsh, R., et al.: J. Inherit. Metab. Dis., 22, 251 (1999); Gonzalez, I., et al.: Am J Med Genet A., 134, 409 (2005); MacKenzie, J., et al.: Biochim Biophys Acta., 1772, 509 (2007)

Formula: C₆H₈O₄

Color and Shape: Neat

Molecular weight: 144.13

Ref: TR-M311565

3-Methylpent-2-enedioic acid

CAS: 5746-90-7

3-Methylpent-2-enedioic acid

Formula: C₆H₈O₄

Purity: 97%

Molecular weight: 144.13

Ref: IN-DG88233

3-Methylglutaconic acid

CAS: 5746-90-7

Purity: 97%

Molecular weight: 144.1260071

Ref: 10-F634807