CAS 579515-63-2

Benzenesulfonamide,3-[[4-[methyl[4-[[[[4-(trifluoromethoxy)phenyl]amino]carbonyl]amino]phenyl]amino]-2-pyrimidinyl]amino]-

Description:

Benzenesulfonamide, specifically the compound with the CAS number 579515-63-2, is a complex organic molecule characterized by its sulfonamide functional group, which is a key feature in many pharmaceuticals. This compound contains multiple aromatic rings and substituents, including trifluoromethoxy and various amino groups, which contribute to its potential biological activity. The presence of the pyrimidine ring suggests that it may interact with biological targets such as enzymes or receptors, making it of interest in medicinal chemistry. The trifluoromethoxy group can enhance lipophilicity and metabolic stability, while the amino groups may facilitate hydrogen bonding and interactions with biological macromolecules. Overall, this compound's structure indicates potential applications in drug development, particularly in targeting specific pathways or diseases. Its synthesis and characterization would involve standard organic chemistry techniques, and its properties would be assessed through various analytical methods to determine its efficacy and safety in potential therapeutic applications.

Formula: C₂₅H₂₂F₃N₇O₄S

GW806742X

CAS: 579515-63-2

GW806742X inhibits MLKL with Kd 9.3 μM, preventing necroptosis; also targets VEGFR2.

Formula: C₂₅H₂₂F₃N₇O₄S

Purity: 98.3%

Color and Shape: Solid

Molecular weight: 573.55

Ref: TM-T11520

GW806742X

CAS: 579515-63-2

Formula: C₂₅H₂₂F₃N₇O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 573.5469

Ref: IN-DA00ELYY

3-((4-(Methyl(4-(3-(4-(Trifluoromethoxy)Phenyl)Ureido)Phenyl)Amino)Pyrimidin-2-Yl)Amino)Benzenesulfonamide

CAS: 579515-63-2

3-((4-(Methyl(4-(3-(4-(Trifluoromethoxy)Phenyl)Ureido)Phenyl)Amino)Pyrimidin-2-Yl)Amino)Benzenesulfonamide

Purity: 98%

Molecular weight: 573.55g/mol

Ref: 54-PC105190

GW806742X

CAS: 579515-63-2

GW806742X

Purity: ≥98%

Molecular weight: 573.55g/mol

Ref: 54-BUP05816

GW806742X

CAS: 579515-63-2

GW806742X is a potent and selective inhibitor of caspase-independent cell death. It provides a new therapeutic option for the treatment of inflammatory diseases, bowel disease, and leukemia. GW806742X has been shown to inhibit the activation of aurora kinases, which are key regulators in the inflammatory response. The compound also blocks necroptosis induced by complement-dependent cytotoxicity or cellular inflammatory stimuli. GW806742X inhibits the release of proinflammatory cytokines and chemokines such as IL-1β and TNFα, which may be due to its ability to block NF-κB activity.

Formula: C₂₅H₂₂F₃N₇O₄S

Purity: Min. 95%

Molecular weight: 573.55 g/mol

Ref: 3D-EYA51563