CAS 5798-75-4

Ethyl 4-bromobenzoate

Description:

Ethyl 4-bromobenzoate is an organic compound with the molecular formula C10H10BrO2. It is classified as an aromatic ester, derived from the reaction of 4-bromobenzoic acid and ethanol. This compound typically appears as a colorless to pale yellow liquid with a characteristic sweet, floral odor. Ethyl 4-bromobenzoate is known for its moderate solubility in organic solvents such as ethanol and ether, while being less soluble in water due to its hydrophobic aromatic structure. It is often used in organic synthesis as an intermediate for the preparation of various pharmaceuticals and agrochemicals. The presence of the bromine atom enhances its reactivity, making it a useful building block in electrophilic substitution reactions. Additionally, it exhibits properties typical of esters, such as being relatively stable under normal conditions but susceptible to hydrolysis in the presence of strong acids or bases. Safety precautions should be taken when handling this compound, as it may pose health risks if inhaled or ingested.

Formula: C₉H₉BrO₂

InChI: InChI=1S/C9H9BrO2/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6H,2H2,1H3

InChI key: InChIKey=XZIAFENWXIQIKR-UHFFFAOYSA-N

SMILES: C(OCC)(=O)C1=CC=C(Br)C=C1

Synonyms:

• 4-(Ethoxycarbonyl)-1-bromobenzene
• 4-Bromobenzoic acid ethyl ester
• 4-Carbethoxyphenyl bromide
• Benzoic acid, 4-bromo-, ethyl ester
• Benzoic acid, p-bromo-, ethyl ester
• Ethyl 4-bromobenzoate, (4-Bromobenzoic acid ethyl ester)
• Ethyl p-bromobenzoate
• NSC 67387
• p-(Ethoxycarbonyl)phenyl bromide
• p-Bromobenzoic acid ethyl ester
• Ethyl 4-bromobenzoate

Ethyl 4-Bromobenzoate

CAS: 5798-75-4

Formula: C₉H₉BrO₂

Purity: >98.0%(GC)

Color and Shape: Colorless to Light yellow to Light orange clear liquid

Molecular weight: 229.07

Ref: 3B-B1515

Ethyl 4-bromobenzoate, 98+%

CAS: 5798-75-4

Ethyl 4-bromobenzoate undergoes reduction with potassium diisobutyl-t-butoxyaluminum hydride (PDBBA) at 0C to yield aldehydes. Reaction of ethyl 4-bromobenzoate and substituted benzyl chloride with zinc dust and a Pd catalyst is reported. This Thermo Scientific Chemicals brand product was originally

Formula: C₉H₉BrO₂

Purity: 98+%

Color and Shape: Liquid, Clear colorless to yellow

Molecular weight: 229.07

Ref: 02-A11365

4-Bromobenzoic Acid Ethyl Ester

CAS: 5798-75-4

Formula: C₉H₉BrO₂

Purity: 96%

Color and Shape: Liquid

Molecular weight: 229.0706

Ref: IN-DA0033Y6

Ethyl 4-bromobenzoate

CAS: 5798-75-4

Ethyl 4-bromobenzoate

Formula: C₉H₉BrO₂

Purity: 98%

Color and Shape: yellow liquid

Molecular weight: 229.07g/mol

Ref: 54-OR0300

Ethyl 4-bromobenzoate

CAS: 5798-75-4

Ethyl 4-bromobenzoate is a halide that can be synthesized by the cross-coupling reaction with an aryl halide and a boronic acid. This synthesis has been used successfully to prepare benzoates, which are generally more difficult to synthesize than boronic acids. The coupling reaction of ethyl 4-bromobenzoate with an aryl halide and a boronic acid in the presence of copper as catalyst yields ethyl 4-bromobenzoate in high yield. A synergistic interaction occurs between the two reagents, leading to significant cytotoxicity in vitro. This property may be due to the light emission from this compound when it is exposed to ultraviolet light. Ethyl 4-bromobenzoate is also able to inhibit aerobic glycolysis and cancer cell growth in vitro through its ability to inhibit the activity of phosphofructokinase 1 (PFK1

Formula: C₉H₉BrO₂

Purity: Min. 97.5 Area-%

Color and Shape: Clear Liquid

Molecular weight: 229.07 g/mol

Ref: 3D-FE70444

Ethyl 4-bromobenzoate

CAS: 5798-75-4

Formula: C₉H₉BrO₂

Purity: 96%

Color and Shape: Liquid, Clear Liquid

Molecular weight: 229.073

Ref: 10-F078889