CAS 58-38-8

Prochlorperazine

Description:

Prochlorperazine is an antipsychotic medication belonging to the phenothiazine class, primarily used to treat severe nausea and vomiting, as well as psychotic disorders such as schizophrenia. Its chemical formula is C20H24ClN3S, and it features a chlorinated phenothiazine structure, which contributes to its pharmacological properties. Prochlorperazine acts primarily as a dopamine D2 receptor antagonist, which helps to mitigate symptoms of psychosis and control nausea. The substance is typically administered in various forms, including tablets, suppositories, and injections. It is known for its sedative effects and can cause side effects such as drowsiness, dry mouth, and potential extrapyramidal symptoms. Due to its pharmacological profile, prochlorperazine is contraindicated in certain conditions, including hypersensitivity to phenothiazines and in patients with severe central nervous system depression. As with all medications, it should be used under medical supervision, considering potential interactions with other drugs and individual patient health conditions.

Formula: C₂₀H₂₄ClN₃S

InChI: InChI=1S/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3

InChI key: InChIKey=WIKYUJGCLQQFNW-UHFFFAOYSA-N

SMILES: C(CCN1CCN(C)CC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(Cl)C3

Synonyms:

• 2-Chloro-10-(3-[1-methyl-4-piperazinyl]propyl)phenothiazine
• 2-Chloro-10-[3'-(4''-methyl-1''-piperazinyl) propyl]-phenothiazine
• 2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine
• 3-Chloro-10-[3-(1-methyl-4-piperazinyl)propyl]phenothiazine
• 6140Rp
• Bayer A 173
• Capazine
• Chlormeprazine
• Chlorperazine
• Ddd 66604
• Emelent
• Kronocin
• Meterazin
• Meterazine
• N-[γ-(4'-Methylpiperazinyl-1')propyl]-3-chlorophenothiazine
• Nipodal
• Nsc 17478
• Nsc 665801
• Phenothiazine, 2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-
• Proazine
• Prochlorpemazine
• Prochlorperazin
• Prochlorperazine
• Prochlorpromazine
• Proclorperazina
• Rp 6140
• Skf 4657
• Temetid

Prochlorperazine Dimaleate

CAS: 58-38-8, 84-02-6

Formula: C₂₀H₂₄ClN₃S·2C₄H₄O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 606.09

Ref: 3B-P2368

Prochlorperazine Base

CAS: 58-38-8

Formula: C₂₀H₂₄ClN₃S

Purity: 95%

Color and Shape: Solid

Molecular weight: 373.9427

Ref: IN-DA003TYP

Prochlorperazine-d3

CAS: 58-38-8

Formula: C₂₀H₂₁D₃ClN₃S

Molecular weight: 376.97

Ref: 4Z-P-141

Prochlorperazine

CAS: 58-38-8

Formula: C₂₀H₂₄ClN₃S

Molecular weight: 373.94

Ref: 4Z-P-1418

Alprostadil (Prostaglandin E1) Impurity 1

CAS: 58-38-8, 84-02-6

Formula: C₂₀H₃₂O₅

Color and Shape: Off-White Solid

Molecular weight: 352.47

Ref: 4Z-P-144018

Prochlorperazine

Controlled Product

CAS: 58-38-8

Applications Prochlorperazine is antiemetic, antipsychotic; used in treatment of vertigo.
References Taylor, W.B., et al.: Br. J. Clin. Pharmacol., 23, 137 (1987), Ward, A.E., Br. J. Clin. Pract., 42, 228 (1988),

Formula: C₂₀H₂₄ClN₃S

Color and Shape: Yellow

Molecular weight: 373.94

Ref: TR-P755790