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CAS 58-38-8

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Prochlorperazine

Description:
Prochlorperazine is an antipsychotic medication belonging to the phenothiazine class, primarily used to treat severe nausea and vomiting, as well as psychotic disorders such as schizophrenia. Its chemical formula is C20H24ClN3S, and it features a chlorinated phenothiazine structure, which contributes to its pharmacological properties. Prochlorperazine acts primarily as a dopamine D2 receptor antagonist, which helps to mitigate symptoms of psychosis and control nausea. The substance is typically administered in various forms, including tablets, suppositories, and injections. It is known for its sedative effects and can cause side effects such as drowsiness, dry mouth, and potential extrapyramidal symptoms. Due to its pharmacological profile, prochlorperazine is contraindicated in certain conditions, including hypersensitivity to phenothiazines and in patients with severe central nervous system depression. As with all medications, it should be used under medical supervision, considering potential interactions with other drugs and individual patient health conditions.
Formula:C20H24ClN3S
InChI:InChI=1S/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3
InChI key:InChIKey=WIKYUJGCLQQFNW-UHFFFAOYSA-N
SMILES:C(CCN1CCN(C)CC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(Cl)C3
Synonyms:
  • 2-Chloro-10-(3-[1-methyl-4-piperazinyl]propyl)phenothiazine
  • 2-Chloro-10-[3'-(4''-methyl-1''-piperazinyl) propyl]-phenothiazine
  • 2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine
  • 3-Chloro-10-[3-(1-methyl-4-piperazinyl)propyl]phenothiazine
  • 6140Rp
  • Bayer A 173
  • Capazine
  • Chlormeprazine
  • Chlorperazine
  • Ddd 66604
  • See more synonyms
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