CAS 58-39-9

Perphenazine

Description:

Perphenazine is an antipsychotic medication belonging to the phenothiazine class, primarily used to treat schizophrenia and severe anxiety. It functions by blocking dopamine receptors in the brain, which helps to alleviate symptoms of psychosis. Perphenazine is characterized by its chemical formula C20H24N2S and a molecular weight of approximately 324.48 g/mol. The substance appears as a white to off-white crystalline powder, and it is typically administered in tablet form or as an injectable solution. Its solubility is limited in water but more favorable in organic solvents. Perphenazine has a relatively long half-life, allowing for once or twice daily dosing. Common side effects may include sedation, dizziness, and extrapyramidal symptoms, which are movement disorders resulting from dopamine blockade. Due to its potential for serious side effects, including tardive dyskinesia, careful monitoring is essential during treatment. As with all medications, it is crucial to use perphenazine under the guidance of a healthcare professional.

Formula: C₂₁H₂₆ClN₃OS

InChI: InChI=1/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2

InChI key: InChIKey=RGCVKNLCSQQDEP-UHFFFAOYSA-N

SMILES: C(CCN1CCN(CCO)CC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(Cl)C3

Synonyms:

• 1-(2-Hydroxyethyl)-4-[3-(2-chloro-10-phenothiazinyl)propyl]piperazine
• 1-Piperazineethanol, 4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-
• 1-Piperazineethanol, 4-[3-(2-chlorophenothiazin-10-yl)propyl]-
• 2-(4-(3-(2-Chlorophenothiazin-10-Yl)Propyl)Piperazin-1-Yl)Ethanol
• 2-Chloro-10-3-[1-(2-hydroxyethyl)-4-piperazinyl] propyl phenothiazine
• 2-Chloro-10-[3'-(4''-(2'''-hydroxyethyl)piperazinyl)propyl]-phenothiazine
• 2-Chloro-10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazine
• 2-[4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl]ethan-1-ol
• 2-[4-[3-(2-Chloro-phenothiazin-10-yl)-propyl]-piperazin-1-yl]-ethanol
• 4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol
• 4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinethanol
• Chloriprozine
• Chlorperphenazine
• Decentan
• Emesinal
• Etaperazin
• Etaperazine
• Ethaperazine
• Fentazin
• Fentazin syrup
• Fentazine duolets
• Mutabom
• Nsc 150866
• PZC
• PZC (tranquilizer)
• Perfenazina
• Perfenazine
• Perfenil
• Perphenan
• Perphenazin
• Sch 3940
• Thilatazin
• Tranquisan
• Trifaron
• Trilafon
• Trilifan
• Triphenot
• γ-[4-(β-Hydroxyethyl)piperazin-1-yl]propyl-2-chlorophenothiazine
• 1’,1-(2-idrossietil)-4,3-(2-cloro-10-fenotiazil)propilpiperazina
• 4-(3-(2-chlorophenothiazin-10-yl)propyl)-1-piperazineethano
• 4(3-(2-chloro-10h-phenothiazin-10-yl)propyl)-1-piperazineethano
• 4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol
• 1',1-(2-Idrossietil)-4,3-(2-cloro-10-fenotiazil)propilpiperazina
• chlorpiprazine
• 2-(4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol
• 4-(3-(2-Chlorophenothiazin-10-yl)propyl)-1-piperazineethanol
• 2-chloro-10-3-(1-(2-hydroxyethyl)-4-piperazinyl)propylphenothiazine
• component of Etrafon
• PERPHENAZINE

Perphenazine

CAS: 58-39-9

Formula: C₂₁H₂₆ClN₃OS

Purity: >97.0%(T)(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 403.97

Ref: 3B-P1970

PERPHENAZINE FOR SYSTEM SUITABILITY CRS

CAS: 58-39-9

PERPHENAZINE FOR SYSTEM SUITABILITY CRS

Formula: C₂₁H₂₆ClN₃OS

Color and Shape: Powder

Molecular weight: 403.9686

Ref: 41-Y0001045

PERPHENAZINE CRS

CAS: 58-39-9

PERPHENAZINE CRS

Formula: C₂₁H₂₆ClN₃OS

Color and Shape: Powder

Molecular weight: 403.9686

Ref: 41-P0550000

Perphenazine

CAS: 58-39-9

Antidepressants, tranquilizers and other pschotherapeutic agents

Formula: C₂₁H₂₆ClN₃OS

Color and Shape: White Cream Powder

Molecular weight: 403.14851

Ref: 45-1511000

Perphenazine

CAS: 58-39-9

Perphenazine (Trilafon) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.

Formula: C₂₁H₂₆ClN₃OS

Purity: 99.3% - 99.99%

Color and Shape: Solid

Molecular weight: 403.97

Ref: TM-T1090

1-(2-Hydroxyethyl)-4-(3-(2-chloro-10-phenothiazinyl)propyl)piperazine

CAS: 58-39-9

Formula: C₂₁H₂₆ClN₃OS

Purity: 97%

Color and Shape: Solid

Molecular weight: 403.9686

Ref: IN-DA00E92G

Perphenazine

CAS: 58-39-9

Perphenazine

Purity: ≥98%

Molecular weight: 403.97g/mol

Ref: 54-BUP14972

Perphenazine

CAS: 58-39-9

Formula: C₂₁H₂₆ClN₃OS

Color and Shape: White to off-white powder

Molecular weight: 403.97

Ref: 7W-GL2019

Perphenazine

CAS: 58-39-9

Perphenazine

Purity: 97%

Molecular weight: 403.97g/mol

Ref: 54-OR1030089

Perphenazine 1.0 mg/ml in Methanol

CAS: 58-39-9

Color and Shape: Single Solution

Ref: 61-AMP0826.00-01

Perphenazine

CAS: 58-39-9

Color and Shape: Neat

Ref: 61-FOR0826.00

Perphenazine

CAS: 58-39-9

Formula: C₂₁H₂₆ClN₃OS

Color and Shape: Neat

Molecular weight: 403.97

Ref: 04-C15996000

Perphenazine

Controlled Product

CAS: 58-39-9

Formula: C₂₁H₂₆ClN₃OS

Color and Shape: Neat

Molecular weight: 403.97

Ref: 86-MM0826.00

Perphenazine RS

CAS: 58-39-9

Color and Shape: White To Light Yellow

Ref: 2K-1150000021

Fluphenazine EP Impurity E

CAS: 58-39-9

Formula: C₂₁H₂₆ClN₃OS

Molecular weight: 404

Ref: ST-EA-CP-F33005

Perphenazine

Controlled Product

CAS: 58-39-9

Applications D2 dopamine receptor antagonist; α-adrenergic receptor antagonist and σ-receptor agonist; phenothiazine antipsychotic. Inhibits glutamate dehydrogenase in vitro. Antipsychotic.
References Gaertner, H.J., et al.: Drug Metab. Dispos., 3, 437 (1975), O Brien, S., et al.: J. Med. Chem., 48, 1287 (2005), Briggs, K., et al.: Toxicology, 231, 113 (2007), Toga, T., et al.: J. Pharmacol. Sci., 105, 207 (2007),

Formula: C₂₁H₂₆ClN₃OS

Color and Shape: Neat

Molecular weight: 403.97

Ref: TR-P291100

Perphenazine

CAS: 58-39-9

Formula: C₂₁H₂₆ClN₃OS

Purity: 97%+(HPLC);RG

Color and Shape: Solid

Molecular weight: 403.149

Ref: 10-F094523

Perphenazine

CAS: 58-39-9

Perphenazine

Formula: C₂₁H₂₆ClN₃OS

Purity: 99.9%

Color and Shape: Light Yellow Solid

Molecular weight: 403.14851

Ref: 47-422