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CAS 58-39-9

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Perphenazine

Description:
Perphenazine is an antipsychotic medication belonging to the phenothiazine class, primarily used to treat schizophrenia and severe anxiety. It functions by blocking dopamine receptors in the brain, which helps to alleviate symptoms of psychosis. Perphenazine is characterized by its chemical formula C20H24N2S and a molecular weight of approximately 324.48 g/mol. The substance appears as a white to off-white crystalline powder, and it is typically administered in tablet form or as an injectable solution. Its solubility is limited in water but more favorable in organic solvents. Perphenazine has a relatively long half-life, allowing for once or twice daily dosing. Common side effects may include sedation, dizziness, and extrapyramidal symptoms, which are movement disorders resulting from dopamine blockade. Due to its potential for serious side effects, including tardive dyskinesia, careful monitoring is essential during treatment. As with all medications, it is crucial to use perphenazine under the guidance of a healthcare professional.
Formula:C21H26ClN3OS
InChI:InChI=1/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2
InChI key:InChIKey=RGCVKNLCSQQDEP-UHFFFAOYSA-N
SMILES:C(CCN1CCN(CCO)CC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(Cl)C3
Synonyms:
  • 1-(2-Hydroxyethyl)-4-[3-(2-chloro-10-phenothiazinyl)propyl]piperazine
  • 1-Piperazineethanol, 4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-
  • 1-Piperazineethanol, 4-[3-(2-chlorophenothiazin-10-yl)propyl]-
  • 2-(4-(3-(2-Chlorophenothiazin-10-Yl)Propyl)Piperazin-1-Yl)Ethanol
  • 2-Chloro-10-3-[1-(2-hydroxyethyl)-4-piperazinyl] propyl phenothiazine
  • 2-Chloro-10-[3'-(4''-(2'''-hydroxyethyl)piperazinyl)propyl]-phenothiazine
  • 2-Chloro-10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazine
  • 2-[4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl]ethan-1-ol
  • 2-[4-[3-(2-Chloro-phenothiazin-10-yl)-propyl]-piperazin-1-yl]-ethanol
  • 4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol
  • See more synonyms
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