CAS 58-46-8: (±)-Tetrabenazine

Description:(±)-Tetrabenazine is a chemical compound primarily used as a medication for the treatment of movement disorders, particularly in conditions like Huntington's disease and tardive dyskinesia. It is classified as a monoamine depleting agent, specifically targeting the depletion of neurotransmitters such as dopamine. The compound has a complex structure featuring a tetrabenazine core, which contributes to its pharmacological activity. It is known for its ability to reduce involuntary movements by modulating dopaminergic activity in the brain. The substance is typically administered in its hydrochloride salt form and is characterized by its relatively low solubility in water, which influences its bioavailability. Side effects may include sedation, depression, and gastrointestinal disturbances, necessitating careful monitoring during treatment. Due to its effects on neurotransmitter levels, (±)-Tetrabenazine is classified as a controlled substance in some jurisdictions, reflecting its potential for misuse and the need for regulated use in clinical settings.

Formula:C₁₉H₂₇NO₃

InChI:InChI=1/C19H27NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16H,5-7,10-11H2,1-4H3/t14-,16-/s2

InChI key:InChIKey=MKJIEFSOBYUXJB-VTLFJGNJNA-N

SMILES:O=C1CC2C3=CC(OC)=C(OC)C=C3CCN2CC1CC(C)C

Synonyms:
2-Oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizine
2H-Benzo[A]Quinolizin-2-One, 1,3,4,6,7,11B-Hexahydro-9,10-Dimethoxy-3-(2-Methylpropyl)-, (3R,11Br)-Rel-
2H-Benzo[a]quinolizin-2-one, 1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-
2H-Benzo[a]quinolizin-2-one, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, cis-
2H-benzo[a]quinolizin-2-one, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-
3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one
9,10-Dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isochinolin-2-on
9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one
Nsc 169886
Nsc 172187
See more synonyms
Ro 1-9569
Rubigen
Tetrabenazin
Tetrabenazina
Xenazine
cis-2-Oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizine
rel-(3R,11bR)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one

Found 14 products.

Product data	Purity	Price range	Estimated delivery
Tetrabenazine REF: 3B-T2839CAS: 58-46-8	>99.0%(T)(HPLC)	107.00 €~349.00 €	Thu 24 Apr 25
Tetrabenazine ((3RS,11bRS)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one) REF: 45-1649801CAS: 58-46-8	- - -	771.00 €	Wed 30 Apr 25
Tetrabenazine REF: IN-DA003UMFCAS: 58-46-8	98%	39.00 €~323.00 €	Fri 02 May 25
Tetrabenazine REF: TM-T0719CAS: 58-46-8	98% - 99.91%	35.00 €~284.00 €	Fri 02 May 25
Tetrabenazine-d7 REF: 4Z-T-782CAS: 58-46-8	- - -	To inquire	Fri 02 May 25
Tetrabenazine REF: 4Z-T-781CAS: 58-46-8	- - -	To inquire	Fri 02 May 25
Tetrabenazine REF: 54-OR1028221CAS: 58-46-8	99%	32.00 €~1,283.00 €	Fri 02 May 25
Tetrabenazine REF: 54-BUP15812CAS: 58-46-8	≥98%	69.00 €~430.00 €	Fri 02 May 25
Tetrabenazine REF: 7W-GK0293CAS: 58-46-8	- - -	To inquire	Fri 02 May 25
Tetrabenazine REF: 86-MM1633.01CAS: 58-46-8	- - -	341.00 €	Tue 06 May 25
3-ISOBUTYL-9,10-DIMETHOXY-3,4,6,7-TETRAHYDRO-1H-PYRIDO[2,1-A]ISOQUINOLIN-2(11BH)-ONE REF: 10-F301460CAS: 58-46-8	97.0%	To inquire	Tue 13 May 25
Tetrabenazine - Bio-X ™ REF: 3D-BT164463CAS: 58-46-8	Min. 99 Area-%	147.00 €	Mon 12 May 25
Tetrabenazine REF: TR-T284000CAS: 58-46-8	- - -	178.00 €~707.00 €	Wed 11 Jun 25
Tetrabenazine REF: 3D-FT28060CAS: 58-46-8	Min. 95%	106.00 €~962.00 €	Thu 26 Jun 25