CAS 58-73-1: Diphenhydramine
Description:Diphenhydramine is an antihistamine commonly used to relieve symptoms of allergy, hay fever, and the common cold. It is classified as a first-generation H1 receptor antagonist, which means it blocks the action of histamine, a substance in the body that causes allergic symptoms. Chemically, diphenhydramine is characterized by its structure, which includes two phenyl rings connected by an ethylamine chain. This structure contributes to its ability to cross the blood-brain barrier, leading to sedative effects, which is why it is also used as a short-term treatment for insomnia. Diphenhydramine has a relatively low solubility in water but is soluble in organic solvents. Its pharmacological effects can include drowsiness, dry mouth, dizziness, and in some cases, paradoxical reactions such as excitability, especially in children. Due to its sedative properties, caution is advised when operating machinery or driving after consumption. Additionally, it may interact with other medications, so it is important to consult healthcare professionals before use.
Formula:C17H21NO
InChI:InChI=1S/C17H21NO/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16/h3-12,17H,13-14H2,1-2H3
InChI key:InChIKey=ZZVUWRFHKOJYTH-UHFFFAOYSA-N
SMILES:O(CCN(C)C)C(C=1C=CC=CC1)C=2C=CC=CC2
- Synonyms:
- 2-(Benzhydryloxy)-N,N-dimethylethanamine
- 2-(Benzhydryloxy)-N,N-dimethylethylamine
- 2-(Diphenylmethoxy)-N,N-dimethylethanamine
- 2-(Diphenylmethoxy)-N,N-dimethylethylamine
- 2-Benzhydryloxyethyldimethylamine
- Benzhydramine
- DPH
- Difenhidramina
- Dimedrol base
- Diphenhydramin
- See more synonyms
- Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl-
- Ethylamine, 2-(diphenylmethoxy)-N,N-dimethyl-
- Far 90X2
- N,N-Dimethyl-2-(diphenylmethoxy)ethylamine
- N-[2-(Diphenylmethoxy)ethyl]-N,N-dimethylamine
- Nsc 665800
- O-Benzhydryldimethylaminoethanol
- Probedryl
- Restamin
- α-(2-Dimethylaminoethoxy)diphenylmethane
- β-Dimethylaminoethanol diphenylmethyl ether
- β-Dimethylaminoethyl benzhydryl ether
- β-Dimethylaminoethylbenzhydrylether
- Diphenylhydramine