CAS 58-93-5
:Hydrochlorothiazide
Description:
Hydrochlorothiazide is a thiazide diuretic commonly used in the treatment of hypertension and edema associated with heart failure, liver cirrhosis, and renal disorders. Its chemical formula is C7H8ClN3O4S, and it features a sulfonamide group, which is integral to its mechanism of action. Hydrochlorothiazide works by inhibiting the sodium-chloride symporter in the distal convoluted tubule of the nephron, leading to increased excretion of sodium and water, thereby reducing blood volume and lowering blood pressure. The substance is typically administered orally and is known for its relatively rapid onset of action. Hydrochlorothiazide is characterized by its moderate solubility in water and is often formulated in combination with other antihypertensive agents to enhance therapeutic efficacy. Common side effects may include electrolyte imbalances, particularly hypokalemia, and it may also affect glucose metabolism. As with any medication, it is essential to use hydrochlorothiazide under medical supervision to monitor for potential adverse effects and interactions with other drugs.
Formula:C7H8ClN3O4S2
InChI:InChI=1S/C7H8ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-2,10-11H,3H2,(H2,9,12,13)
InChI key:InChIKey=JZUFKLXOESDKRF-UHFFFAOYSA-N
SMILES:O=S1(=O)C=2C(=CC(Cl)=C(S(N)(=O)=O)C2)NCN1
Synonyms:- 3,4-Dihydrochlorothiazide
- 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
- 6-Chloro-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
- 6-Chloro-7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide
- 6-Chloro-7-sulfamoyl-3,4-dihydrobenzo-1,2,4-thiadiazine-1,1-dioxide
- Acuretic
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- Hypothiazide (C7H8ClN3O4S2)
- Hypothiazide (C<sub>7</sub>H<sub>8</sub>ClN<sub>3</sub>O<sub>4</sub>S<sub>2</sub>)
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- Nsc 53477
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Hydrochlorothiazide
CAS:Formula:C7H8ClN3O4S2Purity:>97.0%(HPLC)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:297.73HYDROCHLOROTHIAZIDE CRS
CAS:<p>HYDROCHLOROTHIAZIDE CRS</p>Formula:C7H8ClN3O4S2Color and Shape:Crystalline Powder. White. Powder.Molecular weight:297.7391HYDROCHLOROTHIAZIDE FOR PEAK IDENTIFICATION CRS
CAS:<p>HYDROCHLOROTHIAZIDE FOR PEAK IDENTIFICATION CRS</p>Formula:C7H8ClN3O4S2Molecular weight:297.7391HYDROCHLOROTHIAZIDE RS
CAS:<p>HYDROCHLOROTHIAZIDE RS</p>Formula:C7H8ClN3O4S2Molecular weight:297.7391Hydrochlorothiazide
CAS:HydrochlorothiazideFormula:C7H8ClN3O4S2Purity:99.3%Color and Shape:Off-WhiteMolecular weight:296.96448Hydrochlorothiazide
CAS:<p>Sulfonamides used as drugs</p>Formula:C7H8ClN3O4S2Color and Shape:White PowderMolecular weight:296.96448Hydrochlorothiazide
CAS:<p>Hydrochlorothiazide (HCTZ) 是一种口服有效的噻嗪类的利尿药，可抑制转化 TGF-β/Smad 信号通路。它通过打开钙激活钾 (KCA) 通道发挥直接的血管松弛作用。它改善心脏功能，减少纤维化并具有降压作用。</p>Formula:C7H8ClN3O4S2Purity:99.43% - 99.50%Color and Shape:Crystals Physical Description Crystals Or White Powder (Ntp 1992)Molecular weight:297.74Hydrochlorothiazide
CAS:Formula:C7H8ClN3O4S2Purity:(HPLC) 98.0 - 102.0 % (dried basis)Color and Shape:White crystalline powderMolecular weight:297.74Hydrochlorothiazide, USP grade
CAS:Formula:C7H8ClN3O4S2Purity:≤ 0.5%Color and Shape:White to almost white crystalline powderMolecular weight:297.74Hydrochlorothiazide
CAS:Controlled ProductFormula:C7H8ClN3O4S2Color and Shape:NeatMolecular weight:297.74Hydrochlorothiazide
CAS:<p>Hydrochlorothiazide</p>Purity:98%Color and Shape:White SolidMolecular weight:297.74g/molHydrochlorothiazide-13C,15N2,d2
CAS:Controlled Product<p>Applications Labelled Hydrochlorothiazide (H714560). Hydrochlorothiazide is a carbonic anhydrase inhibitor as a diuretic.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961), Deppeler, H.P., et al.: Anal. Profiles Drug Subs., 10, 405 (1981),<br></p>Formula:C613CH6D2ClN15N2O4S2Color and Shape:NeatMolecular weight:302.73Hydrochlorothiazide
CAS:Formula:C7H8ClN3O4S2Color and Shape:White Crystalline PowderMolecular weight:297.74Hydrochlorothiazide - Bio-X ™
CAS:Controlled Product<p>Hydrochlorothiazide is a thiazide diuretic. It is used to treat high blood pressure and fluid retention. Hydrochlorothiazide lowers levels of electrolytes such as potassium, sodium, and chloride in the body by increasing the amount of water that is excreted. This drug has been shown to be effective in reducing disease activity and improving quality of life for patients with chronic inflammatory conditions such as rheumatoid arthritis and psoriasis.</p>Formula:C7H8ClN3O4S2Purity:Min. 95%Color and Shape:PowderMolecular weight:297.74 g/mol
