Description:Angiotensin I and II are peptides that play crucial roles in the regulation of blood pressure and fluid balance in the body. Angiotensin I is a precursor that is converted into Angiotensin II, a potent vasoconstrictor, by the action of the enzyme angiotensin-converting enzyme (ACE). The sequence of amino acids in these peptides is critical for their biological activity, with Angiotensin II being particularly significant in stimulating aldosterone secretion, increasing sodium reabsorption, and promoting thirst. The CAS number 58442-64-1 specifically refers to a synthetic form of Angiotensin II, which is often used in research and clinical settings to study cardiovascular function and the renin-angiotensin system. Characteristically, these peptides are hydrophilic, have a relatively short half-life in circulation, and their activity is tightly regulated by various physiological mechanisms. Understanding their structure and function is essential for developing drugs that target the renin-angiotensin system in conditions such as hypertension and heart failure.
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