RAAS
RAAS (Renin-Angiotensin-Aldosterone System) inhibitors are compounds that target the RAAS pathway, which is primarily known for its role in regulating blood pressure and fluid balance but also influences angiogenesis. The RAAS pathway can contribute to the development of new blood vessels in tumors, thus supporting their growth. Inhibiting components of the RAAS can therefore have anti-angiogenic effects, making these inhibitors valuable in the treatment of certain cancers and vascular disorders. At CymitQuimica, we offer a range of high-quality RAAS inhibitors to support your research in cardiovascular biology, oncology, and angiogenesis.
Found 97 products for "RAAS".
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Losartan potassium
CAS:Losartan potassium (DuP-753 potassium) , an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to theFormula:C22H22ClN6OPurity:99.85% - >99.99%Color and Shape:White SolidMolecular weight:421.903Valsartan Methyl Ester
CAS:Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.Formula:C25H31N5O3Purity:99.54%Color and Shape:White SolidMolecular weight:449.5453Pomisartan 2HCl
Pomisartan 2HCl (BIBR363 2HCL) is a small molecule AT1R antagonist used to study heart failure and hypertension.Formula:C31H32Cl2N4O2Purity:99.88%Color and Shape:SoildMolecular weight:563.52Olmesartan Medoxomil
CAS:Olmesartan Medoxomil (Benicar) is an angiotensin II type 1 receptor blocker that is used to manage hypertension.Formula:C30H32N6O6Purity:99.89% - 99.9%Color and Shape:SolidMolecular weight:572.6117Zansecimab
CAS:Zansecimab (LY-3127804) is a monoclonal antibody targeting angiopoietin 2 (Ang 2) for the study of cardiovascular and immune diseases.Purity:97.8% (SDS-PAGE); 99.7% (SEC-HPLC) - 97.8% (SDS-PAGE); 99.7% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:145.23 kDa (Predicted)Losartan
CAS:Losartan (DuP-753) is an angiotensin II receptor antagonist.Formula:C22H23ClN6OPurity:99.48% - >99.99%Color and Shape:SolidMolecular weight:422.911TRV055 acetate
TRV055 acetate is a ligand of angiotensin II type 1 receptor and stimulates cellular Gq-mediated signaling.Formula:C44H61N9O11Purity:99.94%Color and Shape:SolidMolecular weight:892.01Angiotensin II (1-4), human
CAS:Angiotensin II constricts blood vessels and boosts blood pressure by escalating norepinephrine release.Formula:C24H37N7O8Purity:98%Color and Shape:SolidMolecular weight:551.59Saralasin
CAS:Saralasin: angiotensin II antagonist (Ki=0.32 nM) with partial agonist activity, for renovascular & renin-dependent hypertension research.Formula:C42H65N13O10Purity:98%Color and Shape:SolidMolecular weight:912.06[Sar1, Ile8]-Angiotensin II
CAS:[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.Formula:C46H73N13O10Purity:98%Color and Shape:SolidMolecular weight:968.15Angiotensin II (5-8), human
CAS:Angiotensin II (5-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin IIFormula:C26H36N6O5Purity:98%Color and Shape:SolidMolecular weight:512.6012Angiotensin II (1-4), human TFA
Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.Formula:C26H38F3N7O10Purity:98%Color and Shape:SolidMolecular weight:665.62Angiotensin amide
CAS:Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.Formula:C49H70N14O11Purity:98%Color and Shape:SolidMolecular weight:1031.17Pemivibart
Pemivibart is an anti-SARS-CoV-2 RBD mAb that blocks ACE2 binding for immunocompromised patients.Molecular weight:~150 kDaAliskiren-D6 hydrochloride
CAS:Aliskiren (CGP 60536) D6 Hydrochloride is a deuterium-labeled Aliskiren. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).Formula:C30H54ClN3O6Purity:98%Color and Shape:SolidMolecular weight:594.26[Sar1, Ile8]-Angiotensin II acetate
'[Sar1, Ile8]-Angiotensin II acetate triggers oxidases and prompts superoxide in muscles; has varied vascular impacts.Formula:C48H77N13O12Purity:99.36%Color and Shape:SolidMolecular weight:1028.2Handle region peptide, rat
CAS:Rat handle region peptide acts as prorenin receptor blocker, curbs diabetic kidney disease, and reduces eye inflammation.Formula:C54H101N15O12SPurity:98%Color and Shape:SolidMolecular weight:1184.54TRV120055
CAS:TRV120055 is a Gq-biased agonist with 10x more efficacy on AT1R-Gq than AT1R-βarr2.Formula:C34H54N12O7Molecular weight:742.8688Evazarsen sodium
CAS:Evazarsen sodium, an angiotensinogen synthesis inhibitor, possesses antihypertensive properties [1].Formula:C296H414N86O146P20S19Na20Color and Shape:SolidMolecular weight:9201.6Azilsartan Medoxomil Potassium
CAS:Azilsartan Medoxomil Potassium (TAK-491 Potassium) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.Formula:C30H23N4O8·KPurity:99.99%Color and Shape:SolidMolecular weight:606.62
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