CAS 58479-61-1

tert-Butyldiphenylsilyl chloride

Description:

Tert-Butyldiphenylsilyl chloride, with the CAS number 58479-61-1, is an organosilicon compound characterized by the presence of a tert-butyl group and two phenyl groups attached to a silicon atom, along with a chloride functional group. This compound typically appears as a colorless to pale yellow liquid and is known for its reactivity, particularly as a silylating agent in organic synthesis. It is commonly used to protect hydroxyl groups in alcohols and phenols during various chemical reactions, facilitating the formation of silyl ethers. The presence of the bulky tert-butyl group imparts steric hindrance, which can influence the selectivity and reactivity of the compound in synthetic applications. Additionally, tert-butyldiphenylsilyl chloride is sensitive to moisture and should be handled under anhydrous conditions to prevent hydrolysis, which can lead to the formation of unwanted byproducts. Overall, its unique structure and reactivity make it a valuable tool in the field of organic chemistry, particularly in the synthesis of complex molecules.

Formula: C₁₆H₁₉ClSi

InChI: InChI=1S/C16H19ClSi/c1-16(2,3)18(17,14-10-6-4-7-11-14)15-12-8-5-9-13-15/h4-13H,1-3H3

InChI key: InChIKey=MHYGQXWCZAYSLJ-UHFFFAOYSA-N

SMILES: [Si](C(C)(C)C)(Cl)(C1=CC=CC=C1)C2=CC=CC=C2

Synonyms:

• (1,1-Dimethylethyl)diphenylsilyl chloride
• (Chloro)(tert-butyl)diphenylsilane
• 1,1′-[Chloro(1,1-dimethylethyl)silylene]bis[benzene]
• Benzene, 1,1'-[chloro(1,1-dimethylethyl)silylene]bis-
• Chloro(1,1-dimethylethyl)diphenylsilane
• Chlorodiphenyl-tert-butylsilane
• Diphenyl-tert-butylsilyl chloride
• Nsc 617386
• Silane, Tert-Butyl-Diphenylchloro-
• TBDPSCl
• TDBPSCl
• Terc-Butilclorodifenilsilano
• t-Butylchlorodiphenylsilane
• t-Butyldiphenylchlorosilane
• tert-Butylchlordiphenylsilan
• tert-Butylchlorodiphenylsilane
• tert-Butyldiphenylchlorosilane
• tert-Butyldiphenylsilyl chloride

tert-Butyldiphenylchlorosilane

CAS: 58479-61-1

Formula: C₁₆H₁₉ClSi

Purity: >97.0%(GC)

Color and Shape: Colorless to Light orange to Yellow clear liquid

Molecular weight: 274.86

Ref: 3B-B1223

tert-Butyldiphenylchlorosilane, 97%

CAS: 58479-61-1

tert-Butyldiphenylchlorosilane acts as a silylating reagent used to protect alcohols and in the preparation of silyl ethers. It plays a major role as a raw material and a precursor in organic synthesis and pharmaceuticals. It is also used for the synthesis of interphenylene phenyloxazoles which can

Formula: C₁₆H₁₉ClSi

Purity: 97%

Color and Shape: Liquid, Clear colorless to yellow or pink

Molecular weight: 274.86

Ref: 02-A12721

tert-Butyldiphenylchlorosilane

CAS: 58479-61-1

Formula: C₁₆H₁₉ClSi

Purity: 98%

Color and Shape: Liquid

Molecular weight: 274.8606

Ref: IN-DA0035NJ

(tert-Butyl)(chloro)diphenylsilane

CAS: 58479-61-1

(tert-Butyl)(chloro)diphenylsilane

Formula: C₁₆H₁₉ClSi

Purity: ≥95%

Color and Shape: clear. light orange liquid

Molecular weight: 274.86056g/mol

Ref: 54-OR5837

tert-Butyl diphenylchlorosilane

CAS: 58479-61-1

Tert-butyl diphenylchlorosilane is a chemical compound that belongs to the group of organosilicon compounds. It is used for the preparation of various organosilicon compounds, such as trifluoroacetic acid, which is used in analytical chemistry. The synthesis of tert-butyl diphenylchlorosilane starts with the reaction between hydrochloric acid and sodium citrate. This yields a phosphate bond and a hydroxyl group. In order to form the desired product, tert-butyl diphenylchlorosilane, this intermediate is reacted with trifluoroacetic acid in an asymmetric synthesis to yield the desired product. The reaction mechanism of this process involves hydrogen chloride as an electrophile attacking the carbonyl carbon atom in trifluoroacetic acid, leading to an elimination reaction. This elimination reaction results in two possible products: tert-butyl acetate or tert-butyl chloros

Formula: C₁₆H₁₉ClSi

Purity: Min. 97 Area-%

Color and Shape: Clear Liquid

Molecular weight: 274.87 g/mol

Ref: 3D-FB02547

tert-Butyldiphenylchlorosilane

Controlled Product

CAS: 58479-61-1

Applications tert-Butyldiphenylchlorosilane is used to synthesize interphenylene phenyloxazoles, compounds that have antagonistic activity against thromboxane receptors which can be used for treatment of circulatory disorders, angina and stroke.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hadjipavlou–Litina, D. & Kontogiorgis, C.: Int. Elect. J. Mol. Des., 1, 300 (2002); Misra, R., et al.: Bioorg. Med. Chem. Lett., 2, 937 (1992)

Formula: C₁₆H₁₉ClSi

Color and Shape: Neat

Molecular weight: 274.86

Ref: TR-B692415

tert-Butylchlorodiphenylsilane (TBDPSCl) extrapure AR, 98%

CAS: 58479-61-1

Formula: C₁₆H₁₉ClSi

Purity: min. 98%

Color and Shape: Clear, Colourless to slight yellow, Liquid

Molecular weight: 274.86

Ref: SR-32431