CAS 58579-51-4: Anagrelide hydrochloride

Description: Anagrelide hydrochloride is a synthetic compound primarily used as a medication to treat essential thrombocythemia, a condition characterized by elevated platelet counts. It functions as a selective inhibitor of platelet aggregation and is known to reduce platelet production by acting on megakaryocytes in the bone marrow. The substance is a white to off-white crystalline powder, soluble in water and methanol, which facilitates its administration in a clinical setting. Anagrelide hydrochloride has a molecular formula that reflects its complex structure, and it is typically administered orally. Its pharmacokinetics involve rapid absorption, with peak plasma concentrations occurring within a few hours post-administration. The drug is metabolized primarily in the liver, and its elimination half-life allows for once or twice daily dosing. Common side effects may include headache, diarrhea, and palpitations, necessitating monitoring of patients for potential adverse reactions. Overall, Anagrelide hydrochloride represents a targeted therapeutic approach in managing disorders associated with high platelet counts.

Formula: C₁₀H₇Cl₂N₃O·ClH

InChI: InChI=1S/C10H7Cl2N3O.ClH/c11-6-1-2-7-5(9(6)12)3-15-4-8(16)14-10(15)13-7;/h1-2H,3-4H2,(H,13,14,16);1H

InChI key: InChIKey=TVWRQCIPWUCNMI-UHFFFAOYSA-N

SMILES: Cl.O=C1N=C2NC3=CC=C(Cl)C(Cl)=C3CN2C1

Synonyms:

• 6,7-Dichloro-1,5-dihydroimidazo(2,1-b)-quinazolin-2(3H)-one monohydrochloride
• 6,7-Dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2(3H)-one Hydrochloride
• 6,7-dichloro-5,10-dihydroimidazo[2,1-b]quinazolin-2(3H)-one hydrochloride (1:1)
• Agrelin
• Agrylin
• Anagrelide hcl
• Bl 4162A
• Bmy 26538-01
• Imidazo[2,1-b]quinazolin-2(3H)-one, 6,7-dichloro-1,5-dihydro-, hydrochloride (1:1)
• Imidazo[2,1-b]quinazolin-2(3H)-one, 6,7-dichloro-1,5-dihydro-, monohydrochloride
• Anagrelide hydrochloride

Anagrelide hydrochloride

CAS: 58579-51-4

• Formula: C₁₀H₈Cl₃N₃O
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 292.549

Anagrelide hydrochloride hydrate

CAS: 58579-51-4

• Formula: C₁₀H₇Cl₂N₃O
• Molecular weight: 256.09

6,7-Dichloro-5,10-Dihydroimidazo[2,1-B]Quinazolin-2(3H)-One Hydrochloride

CAS: 58579-51-4

• Purity: 98%
• Molecular weight: 292.55g/mol

Anagrelide HCl

CAS: 58579-51-4

• Formula: C₁₀H₇Cl₂N₃O·HCl
• Molecular weight: 256.09 36.46

Anagrelide hydrochloride

CAS: 58579-51-4

• Purity: 99.77%
• Molecular weight: 292.55g/mol

Anagrelide Hydrochloride

CAS: 58579-51-4

• Formula: C₁₀H₇Cl₂N₃O·ClH
• Color and Shape: Neat
• Molecular weight: 292.55

Anagrelide hydrochloride

CAS: 58579-51-4

Anagrelide hydrochloride (BL4162A) serves as a treatment for essential thrombocytosis.

• Formula: C₁₀H₇Cl₂N₃O·HCl
• Purity: 99.58%
• Color and Shape: Off-White Powder
• Molecular weight: 292.55

Anagrelide Hydrochloride

CAS: 58579-51-4

Applications Anagrelide Hydrochloride is a phosphodiesterase inhibitor with antiplatelet activity. Used as an antithrombocythemic. Potent …

• Formula: C₁₀H₇Cl₂N₃O·ClH
• Color and Shape: White
• Molecular weight: 292.55

6,7-Dichloro-5,10-dihydroimidazo[2,1-b]quinazolin-2(3H)-one hydrochloride

CAS: 58579-51-4

• Purity: 95.0%
• Molecular weight: 292.5400085449219

Anagrelide HCl - Bio-X ™

CAS: 58579-51-4

Anagrelide is a thrombocytopenic drug that is used to treat thrombocythemia and related conditions. This …

• Formula: C₁₀H₇Cl₂N₃O•HCl
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 292.55 g/mol

Anagrelide hydrochloride

CAS: 58579-51-4

Phosphodiesterase-III inhibitor; thrombocytopenic

• Formula: C₁₀H₇Cl₂N₃O•HCl
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 292.55 g/mol