CAS 58579-51-4
:Anagrelide hydrochloride
Description:
Anagrelide hydrochloride is a synthetic compound primarily used as a medication to treat essential thrombocythemia, a condition characterized by elevated platelet counts. It functions as a selective inhibitor of platelet aggregation and is known to reduce platelet production by acting on megakaryocytes in the bone marrow. The substance is a white to off-white crystalline powder, soluble in water and methanol, which facilitates its administration in a clinical setting. Anagrelide hydrochloride has a molecular formula that reflects its complex structure, and it is typically administered orally. Its pharmacokinetics involve rapid absorption, with peak plasma concentrations occurring within a few hours post-administration. The drug is metabolized primarily in the liver, and its elimination half-life allows for once or twice daily dosing. Common side effects may include headache, diarrhea, and palpitations, necessitating monitoring of patients for potential adverse reactions. Overall, Anagrelide hydrochloride represents a targeted therapeutic approach in managing disorders associated with high platelet counts.
Formula:C10H7Cl2N3O·ClH
InChI:InChI=1S/C10H7Cl2N3O.ClH/c11-6-1-2-7-5(9(6)12)3-15-4-8(16)14-10(15)13-7;/h1-2H,3-4H2,(H,13,14,16);1H
InChI key:InChIKey=TVWRQCIPWUCNMI-UHFFFAOYSA-N
SMILES:ClC1=C2C(NC=3N(C2)CC(=O)N3)=CC=C1Cl.Cl
Synonyms:- 6,7-Dichloro-1,5-dihydroimidazo(2,1-b)-quinazolin-2(3H)-one monohydrochloride
- 6,7-Dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2(3H)-one Hydrochloride
- 6,7-dichloro-5,10-dihydroimidazo[2,1-b]quinazolin-2(3H)-one hydrochloride (1:1)
- Agrelin
- Agrylin
- Anagrelide hcl
- Bl 4162A
- Bmy 26538-01
- Imidazo[2,1-b]quinazolin-2(3H)-one, 6,7-dichloro-1,5-dihydro-, hydrochloride (1:1)
- Imidazo[2,1-b]quinazolin-2(3H)-one, 6,7-dichloro-1,5-dihydro-, monohydrochloride
- Anagrelide hydrochloride
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Found 11 products.
Anagrelide hydrochloride
CAS:Formula:C10H8Cl3N3OPurity:98%Color and Shape:SolidMolecular weight:292.54906,7-Dichloro-5,10-Dihydroimidazo[2,1-B]Quinazolin-2(3H)-One Hydrochloride
CAS:6,7-Dichloro-5,10-Dihydroimidazo[2,1-B]Quinazolin-2(3H)-One HydrochloridePurity:98%Molecular weight:292.55g/molAnagrelide Hydrochloride
CAS:Controlled ProductFormula:C10H7Cl2N3O·ClHColor and Shape:NeatMolecular weight:292.55Anagrelide hydrochloride
CAS:<p>Anagrelide hydrochloride (BL4162A) serves as a treatment for essential thrombocytosis.</p>Formula:C10H7Cl2N3O·HClPurity:99.58%Color and Shape:Off-White PowderMolecular weight:292.55Anagrelide Hydrochloride
CAS:Controlled Product<p>Applications Anagrelide Hydrochloride is a phosphodiesterase inhibitor with antiplatelet activity. Used as an antithrombocythemic. Potent PDE3 inhibitor.<br>References Fleming, J.S., et al.: Thromb. Res., 15, 373 (1979), Seiler, S., et al.: J. Pharmacol. Exp. Ther., 243, 767 (1984), Silverstein, M. N., et al.: N. Engl. J. Med., 318, 1292 (1988), Spencer, C.M., et al.: Drugs, 47, 809 (1994),<br></p>Formula:C10H7Cl2N3O·ClHColor and Shape:WhiteMolecular weight:292.556,7-Dichloro-5,10-dihydroimidazo[2,1-b]quinazolin-2(3H)-one hydrochloride
CAS:Purity:95.0%Molecular weight:292.5400085449219Anagrelide HCl - Bio-X ™
CAS:<p>Anagrelide is a thrombocytopenic drug that is used to treat thrombocythemia and related conditions. This drug works by decreasing the platelet count by suppressing transcription factors that are necessary for the maturation of platelets. This drug is also a phosphodiesterase III inhibitor.</p>Formula:C10H7Cl2N3O•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:292.55 g/molAnagrelide hydrochloride
CAS:<p>Phosphodiesterase-III inhibitor; thrombocytopenic</p>Formula:C10H7Cl2N3O•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:292.55 g/mol
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