CAS 586-89-0

4-Acetylbenzoic acid

Description:

4-Acetylbenzoic acid, also known as p-acetylbenzoic acid, is an aromatic carboxylic acid characterized by the presence of both an acetyl group and a carboxylic acid group attached to a benzene ring. Its molecular formula is C9H10O3, and it features a distinctive structure that includes a carbonyl group (C=O) from the acetyl moiety and a hydroxyl group (–COOH) from the carboxylic acid. This compound typically appears as a white to off-white crystalline solid and is soluble in organic solvents such as ethanol and acetone, but has limited solubility in water. 4-Acetylbenzoic acid is utilized in various applications, including as an intermediate in organic synthesis and in the production of dyes and pharmaceuticals. It exhibits properties such as moderate acidity due to the carboxylic acid group and can participate in various chemical reactions, including esterification and acylation. Safety precautions should be observed when handling this compound, as it may cause irritation to the skin and eyes.

Formula: C₉H₈O₃

InChI: InChI=1S/C9H8O3/c1-6(10)7-2-4-8(5-3-7)9(11)12/h2-5H,1H3,(H,11,12)

InChI key: InChIKey=QBHDSQZASIBAAI-UHFFFAOYSA-N

SMILES: C(C)(=O)C1=CC=C(C(O)=O)C=C1

Synonyms:

• 4-(1-Oxoethyl)benzoic acid
• 4-Acetylbenzoate
• 4-Carboxyacetophenone
• Acetophenone-4-carboxylic acid
• Benzoic acid, 4-acetyl-
• Benzoic acid, p-acetyl-
• NSC 16644
• p-Acetylbenzoic acid
• p-Carboxyacetophenone
• 4-Acetylbenzoci acid
• 4-Acetylbenzoic acid

4-Acetylbenzoic acid

CAS: 586-89-0

4-Acetylbenzoic acid

Formula: C₉H₈O₃

Purity: 97%

Molecular weight: 164.16

Ref: IN-DG7631

4-Acetylbenzoic Acid

CAS: 586-89-0

Formula: C₉H₈O₃

Purity: >98.0%(T)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 164.16

Ref: 3B-A1024

4-Acetylbenzoic acid, 98+%

CAS: 586-89-0

4-Acetylbenzoic acid was used in the preparation of an ester-derivative of paclitaxel. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / ite

Formula: C₉H₈O₃

Purity: 98+%

Color and Shape: White to pale cream, Powder

Molecular weight: 164.16

Ref: 02-A15239

4-Acetylbenzoic Acid

CAS: 586-89-0

Formula: C₉H₈O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 164.1580

Ref: IN-DA003KMU

4-Acetyl benzoic acid

CAS: 586-89-0

4-Acetyl benzoic acid

Formula: C₉H₈O₃

Purity: >99%

Color and Shape: Light red. Solid-Powder

Molecular weight: 164.15802

Ref: 54-OR345603

4-Acetylbenzoic acid

CAS: 586-89-0

Formula: C₉H₈O₃

Molecular weight: 164.16

Ref: 7W-GK5272

4-Acetylbenzoic Acid

Controlled Product

CAS: 586-89-0

Formula: C₉H₈O₃

Color and Shape: Neat

Molecular weight: 164.16

Ref: 86-MM0002.08

4-Acetylbenzoic Acid

CAS: 586-89-0

Formula: C₉H₈O₃

Molecular weight: 164.16

Ref: 4Z-I-0471

4-Acetylbenzoic acid

CAS: 586-89-0

4-Acetylbenzoic acid is a reactive functional group that is used to synthesize esters and amides. It has been shown to have anticancer activity in vitro, which may be due to the disruption of basic cellular proteins involved in DNA replication. 4-Acetylbenzoic acid is soluble in neutral pH and reacts with nucleophiles such as hydroxide ions or alcohols, forming alcohols or acetates respectively. The reaction mechanism for this compound is nucleophilic attack on the carbonyl carbon, followed by loss of water from the leaving group. Significant cytotoxicity has been observed in vitro at concentrations of 2mM and higher. This effect was particularly pronounced for cells exposed to radiation or treated with 4-acetylbenzoic acid before being exposed to radiation.

Formula: C₉H₈O₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 164.16 g/mol

Ref: 3D-FA33613

4-Acetylbenzoic acid

CAS: 586-89-0

Formula: C₉H₈O₃

Purity: 95%

Color and Shape: Solid, Crystalline Powder

Molecular weight: 164.16

Ref: 10-F021711

4-Acetylbenzoic Acid

Controlled Product

CAS: 586-89-0

Formula: C₉H₈O₃

Color and Shape: Neat

Molecular weight: 164.16

Ref: TR-A167960

4-Acetylbenzoic Acid

CAS: 586-89-0

Formula: C₉H₈O₃

Molecular weight: 164.16

Ref: ST-EA-CP-I2061