CAS 586379-66-0

PH 797804

Description:

PH 797804, with the CAS number 586379-66-0, is a chemical compound that has garnered attention in pharmaceutical research, particularly for its potential therapeutic applications. It is classified as a small molecule and is known to act as a selective inhibitor of certain protein kinases, which are crucial in various cellular signaling pathways. The compound's structure typically features a core that allows for specific interactions with target proteins, contributing to its biological activity. PH 797804 has been studied for its effects on cell proliferation and apoptosis, making it a candidate for cancer research. Additionally, its pharmacokinetic properties, such as solubility and stability, are essential for determining its efficacy and safety in clinical settings. As with many investigational compounds, ongoing studies aim to elucidate its mechanism of action, optimal dosing regimens, and potential side effects. Overall, PH 797804 represents a promising area of exploration in the development of targeted therapies in oncology and other fields.

Formula: C₂₂H₁₉BrF₂N₂O₃

InChI: InChI=1S/C22H19BrF2N2O3/c1-12-4-5-14(21(28)26-3)9-18(12)27-13(2)8-19(20(23)22(27)29)30-11-15-6-7-16(24)10-17(15)25/h4-10H,11H2,1-3H3,(H,26,28)

InChI key: InChIKey=KCAJXIDMCNPGHZ-UHFFFAOYSA-N

SMILES: O=C1N(C(C)=CC(OCC2=C(F)C=C(F)C=C2)=C1Br)C3=CC(C(NC)=O)=CC=C3C

Synonyms:

• PH797804
• 3-Bromo-4-[(2,4-difluorobenzyl)oxy]-1-[5-[(methylamino)carbonyl]-2-methylphenyl]-6-methylpyridin-2(1H)-one
• Benzamide, 3-[3-bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxo-1(2H)-pyridinyl]-N,4-dimethyl-
• PH-797804
• CS-45
• 3-(3-Bromo-4-((2,4-difluorobenzyl)oxy)-6-methyl-2-oxopyridin-1(2H)-yl)-N,4-dimethylbenzamide
• 3-Bromo-4-[(2,4-difluorobenzyl)oxy]-1-[5-[(methylamino)carbonyl]-2-methylphenyl]-6-methylpyridin-2(1H)-one
• 3-[3-Bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxo-1(2H)-pyridinyl]-N,4-dimethylbenzamide
• PH 797804
• PH-797804, >=98%
• 3-(4-(2,4-difluorobenzyloxy)-3-bromo-6-methyl-2-oxopyridin-1(2H)-yl)-N,4-dimethylbenzamide

PH-797804

CAS: 586379-66-0

PH-797804

Formula: C₂₂H₁₉BrF₂N₂O₃

Purity: ≥95%

Molecular weight: 477.3

Ref: 54-BUP07196

PH-797804

CAS: 586379-66-0

Formula: C₂₂H₁₉BrF₂N₂O₃

Purity: 99%

Color and Shape: Solid

Molecular weight: 477.2987

Ref: IN-DA00EF9M

PH-797804

CAS: 586379-66-0

PH-797804 is a pyridinone inhibitor of p38α (IC50: 26 nM, in a cell-free assay); 4-fold more selective versus p38β and does not inhibit JNK2.

Formula: C₂₂H₁₉BrF₂N₂O₃

Purity: 97.90% - 98.27%

Color and Shape: Solid

Molecular weight: 477.299

Ref: TM-T1974

Ph-797804

CAS: 586379-66-0

Ph-797804

Formula: C₂₂H₁₉BrF₂N₂O₃

Purity: 99%

Molecular weight: 477.29866

Ref: 54-BISN0276

PH-797804

CAS: 586379-66-0

3-(3-Bromo-4-((2,4-difluorobenzyl)oxy)-6-methyl-2-oxopyridin-1(2H)-yl)-N,4-dimethylbenzamide

Formula: C₂₂H₁₉BrF₂N₂O₃

Purity: 99%

Molecular weight: 477.3

Ref: IN-DG239280

PH-797804-d5

Controlled Product

CAS: 586379-66-0

Formula: C₂₂H₁₄D₅BrF₂N₂O₃

Color and Shape: Neat

Molecular weight: 482.33

Ref: TR-P399152

PH 797804

CAS: 586379-66-0

p38 MAP kinase inhibitor; anti-inflammatory

Formula: C₂₂H₁₉BrF₂N₂O₃

Purity: Min. 95%

Molecular weight: 477.3 g/mol

Ref: 3D-FP103244