CAS 59-01-8

Kanamycin A

Description:

Kanamycin A is an aminoglycoside antibiotic that is primarily used to treat bacterial infections, particularly those caused by Gram-negative bacteria. It is derived from the bacterium *Micromonospora kanamycetica*. Kanamycin A exhibits a broad spectrum of antibacterial activity and works by inhibiting protein synthesis in bacteria, leading to cell death. The compound is characterized by its complex structure, which includes multiple amino sugars and a 2-deoxystreptamine core. It is typically administered via injection or intravenously due to its poor absorption in the gastrointestinal tract. Kanamycin A is known for its potential nephrotoxicity and ototoxicity, necessitating careful monitoring of kidney function and hearing in patients receiving treatment. Additionally, resistance to kanamycin can develop, often through enzymatic modification by bacteria. Its use is generally reserved for specific infections, particularly in cases where other antibiotics are ineffective or contraindicated. Overall, kanamycin A remains an important tool in the antibiotic arsenal, particularly in treating multidrug-resistant infections.

Formula: C₁₈H₃₆N₄O₁₁

InChI: InChI=1/C18H36N4O11/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17/h4-18,23-29H,1-3,19-22H2/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-/m1/s1

InChI key: InChIKey=SBUJHOSQTJFQJX-NOAMYHISSA-N

SMILES: O([C@@H]1[C@@H](O)[C@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](N)C[C@H]1N)[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O

Synonyms:

• (1S,2R,3R,4S,6R)-4,6-diamino-3-[(6-amino-6-deoxy-alpha-D-glucopyranosyl)oxy]-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside
• 4))-2-Deoxy-Y-Alpha-D-Glucopyranosyl-(
• 4,6-Diamino-2-Hydroxy-1,3-Cyclohexane3,6’Diamino-3,6'-Dideoxydi-Alpha-D-Gluc
• 4,6-Diamino-2-Hydroxy-1,3-Cyclohexane3,6’Diamino-3,6’-Dideoxydi-Alpha-D-Glucos
• 4,6-Diamino-2-hydroxy-1,3-cyclohexane 3,6'-diamino-3,6'-dideoxydi-α-D-glucoside
• 4,6-Diamino-2-hydroxy-1,3-cyclohexane 3,6′-diamino-3,6′-dideoxydi-α-<span class="text-smallcaps">D</span>-glucoside
• 4,6-Diamino-3-[(6-Amino-6-Deoxyhexopyranosyl)Oxy]-2-Hydroxycyclohexyl 3-Amino-3-Deoxyhexopyranoside
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-3-amino-3-deoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-<smallcap>D</span>-glucopyranosyl-(1→4)]-2-deoxy-
• D-Deoxydi
• D-Streptamine, O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-
• D-Streptamine,O-3-Amino-3-Deoxy-Alpha-D-Glucopyranosyl-(1.Fwdarw.6)-O-[6-Amin
• KM
• Kanacin
• Kanamicina
• Kanamycin A
• Kanamycin Base
• Kanamycine
• O-3-Amino-3-deoxy-α-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→4)]-2-deoxy-<smallcap>D</span>-streptamine
• O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine
• KANAMYCIN
• 1-O-[(1R)-2α-Hydroxy-3β-(3-amino-3-deoxy-α-D-glucopyranosyloxy)-4α,6α-diaminocyclohexane-1β-yl]-6-amino-6-deoxy-α-D-glucopyranose
• km(theantibiotic)
• o-6-deoxy-alpha-d-glucopyranosyl-(1.fwdarw.)]-2-deoxy-
• Kannamycin Monosulfate
• KANAMYCIN BASE ENTERPRISE STANDARD
• KanamycinMonosulfateA
• 4-O-(6-Amino-6-deoxy-α-D-glucopyranosyl)-6-O-(3-amino-3-deoxy-α-D-glucopyranosyl)-2-deoxy-D-streptamine
• (2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-bis(azanyl)-3-[(2S,3R,4S,5S,6R)-4-azanyl-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxy-cyclohexyl]oxy-oxane-3,4,5-triol
• glucopyranoside,4,6-diamino-2-hydroxy-1,3-cyclohexylene3,6’diamino-3,6’-dideo
• d-xydi
• y-alpha-d-glucopyranosyl-(1-4))-2-deoxy-
• (2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]tetrahydropyran-3,4,5-triol
• (2R,3S,4S,5R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol
• glucopyranoside,4,6-diamino-2-hydroxy-1,3-cyclohexylene3,6’-diamino-3,6’-di
• 6-O-(3-Amino-3-deoxy-α-D-glucopyranosyl)-4-O-(6-amino-6-deoxy-α-D-glucopyranosyl)-2-deoxy-D-streptamine

Kanamycin Monosulfate

CAS: 25389-94-0, 59-01-8, 8063-07-8

Formula: C₁₈H₃₆N₄O₁₁·H₂SO₄

Purity: >94.0%(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 582.58

Ref: 3B-K0047

Kanamycin A

CAS: 59-01-8

Formula: C₁₈H₃₆N₄O₁₁

Purity: 97%

Color and Shape: Solid

Molecular weight: 484.4986

Ref: IN-DA01E3XP

Kanamycin A

CAS: 59-01-8

Kanamycin A (KanamycinA) is an aminoglycoside antibiotic with antibacterial and antiviral activity that inhibits bacterial and viral replication.

Formula: C₁₈H₃₆N₄O₁₁

Purity: 97.72% - 99.96%

Color and Shape: White Solid

Molecular weight: 484.5

Ref: TM-T0793L

Kanamycin A

CAS: 59-01-8

Kanamycin A

Formula: C₁₈H₃₆N₄O₁₁

Purity: ≥98%

Color and Shape: Solid

Molecular weight: 484.5

Ref: 54-BUP17386

Amikacin EP Impurity D

CAS: 59-01-8

Formula: C₁₈H₃₆N₄O₁₁

Color and Shape: White To Off-White Solid

Molecular weight: 484.50

Ref: 4Z-A-144004

KANAMYCIN

CAS: 59-01-8

Purity: 97%;RG

Color and Shape: Liquid

Molecular weight: 484.5029907

Ref: 10-F824194

Kanamycin A

CAS: 59-01-8

Inhibitor of protein synthesis; aminoglycoside

Formula: C₁₈H₃₆N₄O₁₁

Purity: Min. 95%

Color and Shape: White Clear Liquid

Molecular weight: 484.5 g/mol

Ref: 3D-AK30116

Kanamycin

CAS: 59-01-8

Formula: C₁₈H₃₆N₄O₁₁

Molecular weight: 484.5

Ref: ST-EA-CP-K6000

Amikacin EP Impurity D

CAS: 59-01-8

Formula: C₁₈H₃₆N₄O₁₁

Molecular weight: 484.5

Ref: ST-EA-CP-A190004