CAS 59198-70-8
:Diflucortolone valerate
Description:
Diflucortolone valerate is a synthetic corticosteroid used primarily for its anti-inflammatory and immunosuppressive properties. It is characterized by its ability to reduce inflammation and alleviate symptoms associated with various dermatological conditions, such as eczema and psoriasis. The compound is typically formulated as a topical ointment or cream, allowing for localized treatment with minimal systemic absorption. Its mechanism of action involves the inhibition of inflammatory mediators and modulation of immune responses. Diflucortolone valerate is known for its potency, which is generally classified as a mid-strength corticosteroid, making it effective for moderate to severe inflammatory skin disorders. Additionally, it has a favorable safety profile when used as directed, although potential side effects may include skin irritation or atrophy with prolonged use. The chemical structure includes a valerate ester, contributing to its pharmacokinetic properties and enhancing its therapeutic efficacy. Overall, Diflucortolone valerate is a valuable option in dermatological therapy, providing relief from inflammation while minimizing adverse effects when used appropriately.
Formula:C27H36F2O5
InChI:InChI=1S/C27H36F2O5/c1-5-6-7-23(33)34-14-21(31)24-15(2)10-17-18-12-20(28)19-11-16(30)8-9-26(19,4)27(18,29)22(32)13-25(17,24)3/h8-9,11,15,17-18,20,22,24,32H,5-7,10,12-14H2,1-4H3/t15-,17+,18+,20+,22+,24-,25+,26+,27+/m1/s1
InChI key:InChIKey=HHJIUUAMYGBVSD-YTFFSALGSA-N
SMILES:F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@@H](C(COC(CCCC)=O)=O)[C@H](C)C3)[H])(C[C@H](F)C=4[C@]2(C)C=CC(=O)C4)[H]
Synonyms:- (6Alpha,11Beta,16Alpha)-6,9-Difluoro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Pentanoate
- (6alpha,11beta,16alpha)-6,9-Difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl valerate
- (6α,11β,16α)-6,9-Difluoro-11-hydroxy-16-methyl-21-[(1-oxopentyl)oxy]pregna-1,4-diene-3,20-dione
- 59198-70-8
- Afusona
- Diflucortolone 21-valerate
- Diflucortolone valerate (JAN)
- Neriforte
- Nerisona
- Nerisone
- Nerisone Forte
- Pentanoic Acid, (6Alpha,11Beta,16Alpha)-6,9-Difluoro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Ester
- Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11-hydroxy-16-methyl-21-[(1-oxopentyl)oxy]-, (6α,11β,16α)-
- Temetex
- Texmeten
- Travazol
- Youtolon[Tatsumi]
- See more synonyms
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Found 12 products.
Diflucortolone valerate
CAS:Diflucortolone valerateFormula:C27H36F2O5Purity:98.8%Color and Shape:Off White SolidMolecular weight:478.25308Diflucortolone 21-valerate
CAS:Formula:C27H36F2O5Purity:97%Color and Shape:SolidMolecular weight:478.5685Diflucortolone Valerate
CAS:Controlled ProductFormula:C27H36F2O5Color and Shape:NeatMolecular weight:478.57Diflucortolone valerate
CAS:<p>Diflucortolone valerate (Diflucortolone 21-valerate) is a corticosteroid esterified with valeric acid. It helps to reduce itching, redness, and swelling.</p>Formula:C27H36F2O5Purity:99.05%Color and Shape:SolidMolecular weight:478.57Diflucortolone 21-Valerate
CAS:Controlled Product<p>Applications The 9α-fluoro derivative of Fluocortolone (F500500). Anti-inflammmatory.<br>References Kieslich, et al.: Arzneim.-Forsch., 26, 1462 (1976),<br></p>Formula:C27H36F2O5Color and Shape:NeatMolecular weight:478.57Diflucortolone valerate
CAS:Controlled Product<p>Diflucortolone valerate is a corticosteroid that is used to treat inflammatory skin diseases. It is a prodrug that is hydrolyzed in vivo to diflucortolone, its active form. Diflucortolone valerate has been shown to be effective against alopecia areata and mycological skin infections. The optimum concentration of this drug for treating these conditions is 0.5% or less, with side effects such as erythema, scaling, and burning at the application site occurring at higher concentrations. Diflucortolone valerate also has broad-spectrum antimicrobial activity against bacteria and fungi, including methicillin-resistant Staphylococcus aureus (MRSA) isolates.</p>Formula:C27H36F2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:478.57 g/molDiflucortolone valerate impurity standard
CAS:Diflucortolone valerate impurity standardColor and Shape:Off White Solid
