CAS 59530-69-7

Motilin (swine),13-L-leucine-

Description:

Motilin is a peptide hormone primarily involved in regulating gastrointestinal motility. The specific compound you mentioned, "Motilin (swine), 13-L-leucine," refers to a variant of motilin that has been studied in swine, where it plays a crucial role in stimulating gastric motility and promoting the contraction of the gastrointestinal tract. The CAS number 59530-69-7 identifies this particular peptide, which is characterized by its amino acid sequence and structure. Motilin is known to be produced in the small intestine, particularly in the duodenum, and its secretion is influenced by the presence of food in the stomach. The hormone acts on specific receptors in the gastrointestinal tract, leading to increased peristalsis and the coordination of digestive processes. In addition to its physiological roles, motilin and its analogs have been investigated for potential therapeutic applications in gastrointestinal disorders. Overall, motilin is a significant regulator of digestive function, with variations like the one mentioned being important for research in veterinary and human medicine.

Formula: C₁₂₁H₁₉₀N₃₄O₃₅

InChI: InChI=1S/C121H190N34O35/c1-10-65(8)98(153-115(185)87-32-23-53-155(87)118(188)97(64(6)7)152-100(170)71(124)56-67-24-13-11-14-25-67)116(186)151-85(57-68-26-15-12-16-27-68)114(184)154-99(66(9)156)117(187)150-84(58-69-33-35-70(157)36-34-69)102(172)136-60-92(162)137-76(40-46-94(164)165)106(176)148-83(55-63(4)5)112(182)145-77(37-43-88(125)158)107(177)141-74(30-21-51-133-120(129)130)104(174)147-82(54-62(2)3)111(181)146-78(38-44-89(126)159)108(178)144-80(42-48-96(168)169)109(179)140-73(29-18-20-50-123)103(173)143-79(41-47-95(166)167)110(180)142-75(31-22-52-134-121(131)132)105(175)149-86(59-91(128)161)113(183)139-72(28-17-19-49-122)101(171)135-61-93(163)138-81(119(189)190)39-45-90(127)160/h11-16,24-27,33-36,62-66,71-87,97-99,156-157H,10,17-23,28-32,37-61,122-124H2,1-9H3,(H2,125,158)(H2,126,159)(H2,127,160)(H2,128,161)(H,135,171)(H,136,172)(H,137,162)(H,138,163)(H,139,183)(H,140,179)(H,141,177)(H,142,180)(H,143,173)(H,144,178)(H,145,182)(H,146,181)(H,147,174)(H,148,176)(H,149,175)(H,150,187)(H,151,186)(H,152,170)(H,153,185)(H,154,184)(H,164,165)(H,166,167)(H,168,169)(H,189,190)(H4,129,130,133)(H4,131,132,134)/t65-,66+,71-,72-,73-,74-,75+,76-,77-,78-,79-,80-,81+,82-,83-,84-,85-,86+,87-,97-,98-,99-/m0/s1

InChI key: GFOZQXMKARUPQI-DFIBRNPJSA-N

SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@H](CCC(=O)N)C(=O)O)NC(=O)[C@@H]3CCCN3C(=O)[C@H](C(C)C)NC(=O)[C@H](CC4=CC=CC=C4)N

Synonyms:

• Motilin(pig), 13-L-leucine-
• 13-L-Leucine-motilin
• 13Leu-motilin (clone pMTA1)
• 351: PN: US20090175821 SEQID: 432claimed protein
• Kw 1539
• Kw 5139
• [Leu13]-human motilin
• [Leu13]Porcinemotilin
• [Leu13]-Motilin Porcine
• 251:PN: WO0069900 SEQID: 432 unclaimed sequence

[Leu13]-Motilin

CAS: 59530-69-7

[Leu13]-Motilin (KW-5139) is an analogue of the gastrointestinal hormone motilin that induces concentration-dependent contractions in rabbit gastrointestinal

Formula: C₁₂₁H₁₉₀N₃₄O₃₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 2681.01

Ref: TM-T78563

(Leu13)-Motilin (human, porcine) trifluoroacetate salt

CAS: 59530-69-7

Motilin is a gastrointestinal hormone that stimulates gastric motility and the release of pancreatic enzymes. It is also used to treat postoperative ileus, abdominal pain, and gastroduodenal ulcers. Motilin is administered nasogastrically to stimulate the movement of food through the stomach and intestines. The trifluoroacetate salt form is used in this application because it has a longer duration of action than other salts.

Formula: C₁₂₁H₁₉₀N₃₄O₃₅

Purity: Min. 95%

Molecular weight: 2,681.01 g/mol

Ref: 3D-FL109658