CAS 5955-72-6

2-chloro-6-nitro-1H-benzimidazole

Description:

2-Chloro-6-nitro-1H-benzimidazole is a chemical compound characterized by its benzimidazole core, which consists of a fused benzene and imidazole ring. This compound features a chlorine atom at the 2-position and a nitro group at the 6-position of the benzimidazole ring, contributing to its unique reactivity and properties. It is typically a solid at room temperature and may exhibit moderate solubility in organic solvents. The presence of the nitro group often imparts significant electron-withdrawing characteristics, influencing the compound's reactivity in various chemical reactions, including nucleophilic substitutions and electrophilic aromatic substitutions. Additionally, the chlorine substituent can enhance the compound's lipophilicity, affecting its biological activity and potential applications in pharmaceuticals or agrochemicals. Safety data indicates that it should be handled with care, as it may pose health risks upon exposure. Overall, 2-chloro-6-nitro-1H-benzimidazole is of interest in synthetic organic chemistry and may serve as a precursor or intermediate in the synthesis of more complex molecules.

Formula: C₇H₄ClN₃O₂

InChI: InChI=1/C7H4ClN3O2/c8-7-9-5-2-1-4(11(12)13)3-6(5)10-7/h1-3H,(H,9,10)

InChI key: GWSMACGSFHRVFA-UHFFFAOYSA-N

SMILES: c1cc2c(cc1N(=O)=O)[nH]c(Cl)n2

Synonyms:

• 1H-benzimidazole, 2-chloro-5-nitro-
• 2-Chloro-5-nitro-1H-benzimidazole

2-Chloro-5-nitro-1H-benzimidazole

CAS: 5955-72-6

2-Chloro-5-nitro-1H-benzimidazole

Formula: C₇H₄ClN₃O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 197.57856

Ref: 54-OR15280

2-Chloro-6-nitro-1H-benzo[d]imidazole

CAS: 5955-72-6

Formula: C₇H₄ClN₃O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 197.5786

Ref: IN-DA00EE2N

2-Chloro-6-nitro-1H-benzo[d]imidazole

CAS: 5955-72-6

2-Chloro-6-nitro-1H-benzo[d]imidazole

Formula: C₇H₄ClN₃O₂

Purity: 95%

Molecular weight: 197.58

Ref: IN-DG73240

2-Chloro-5-nitro-1H-benzo[d]imidazole

CAS: 5955-72-6

Formula: C₇H₄ClN₃O₂

Purity: 95%

Molecular weight: 197.58

Ref: 10-F234290

2-Chloro-5-nitro-1H-benzo[d]imidazole

CAS: 5955-72-6

2-Chloro-5-nitro-1H-benzo[d]imidazole is a modification of the quinazoline nucleus, which is a potent and selective antagonist of the H2 receptor. 2-Chloro-5-nitro-1H-benzo[d]imidazole has been shown to be an antagonist of the αH2 receptor, inhibiting gastric acid secretion and reducing gastric acidity. It also has been shown to inhibit the release of gonadotropins and testosterone in male rats. In addition, it inhibits the activity of various hormone receptors such as benzodiazepine, histamine H1 and muscarinic receptors.
2-Chloro-5-nitro-1H-benzo[d]imidazole has been shown to have a number of profiles that are either agonistic or antagonistic depending on its binding site.

Formula: C₇H₄ClN₃O₂

Purity: Min. 95%

Molecular weight: 197.58 g/mol

Ref: 3D-FAA95572