CAS 5975-78-0

Zearalanone

Description:

Zearalanone, with the CAS number 5975-78-0, is a mycotoxin produced by certain species of fungi, particularly those in the Fusarium genus. It is a derivative of zearalenone, a non-steroidal estrogenic compound that can mimic the effects of estrogen in animals. Zearalanone is characterized by its chemical structure, which includes a phenolic ring and a lactone moiety, contributing to its biological activity. This compound is primarily known for its estrogenic properties, which can lead to reproductive and developmental issues in livestock and potentially affect human health through the food chain. Zearalanone is often studied in the context of food safety and toxicology, as it can contaminate grains and feed. Its presence in agricultural products necessitates monitoring and regulation to mitigate health risks. Additionally, zearalanone's stability and persistence in the environment raise concerns regarding its long-term effects on ecosystems and animal health.

Formula: C₁₈H₂₄O₅

InChI: InChI=1/C18H24O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,20-21H,2-9H2,1H3

InChI key: InChIKey=APJDQUGPCJRQRJ-LBPRGKRZSA-N

SMILES: OC1=C2C(=CC(O)=C1)CCCCCC(=O)CCC[C@H](C)OC2=O

Synonyms:

• (3S)-14,16-dihydroxy-3-methyl-3,4,5,6,9,10,11,12-octahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione
• (3S)-3,4,5,6,9,10,11,12-Octahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione
• (S)-3,4,5,6,9,10,11,12-Octahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione
• (S)-Zearalanone
• 14,16-dihydroxy-3-methyl-3,4,5,6,9,10,11,12-octahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione
• 1H-2-Benzoxacyclotetradecin-1,7(8H)-dione, 3,4,5,6,9,10,11,12-octahydro-14,16-dihydroxy-3-methyl-, (3S)-
• 1H-2-Benzoxacyclotetradecin-1,7(8H)-dione, 3,4,5,6,9,10,11,12-octahydro-14,16-dihydroxy-3-methyl-, (S)-
• Ccris 9235
• P 1502
• Zanone
• beta-Resorcylic acid, 6-(10-hydroxy-6-oxoundecyl)-, mu-lactone
• β-Resorcylic acid, 6-(10-hydroxy-6-oxoundecyl)-, μ-lactone
• Zearalanone
• Zearalanone (Certified Reference Material)
• Zearalanone solution
• 2,4-Dihydroxy-6-(10-hydroxy-6-oxoundecyl)benzoic acid μ-lactone solution
• (S)-Zearalanone, P 1502, Zanone
• 2-[(S)-10-Hydroxy-6-oxoundecyl]-4,6-dihydroxybenzoic acid 1,2-lactone
• Zearalanone,2,4-Dihydroxy-6-(10-hydroxy-6-oxoundecyl)benzoic acid μ-lactone
• Zearalanone Standard
• 2,4-Dihydroxy-6-(10-hydroxy-6-oxoundecyl)benzoic acid μ-lactone

Zearalanone

CAS: 5975-78-0

Formula: C₁₈H₂₄O₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 320.3802

Ref: IN-DA00EBQU

Zearalanone

CAS: 5975-78-0

Formula: C₁₈H₂₄O₅

Molecular weight: 320.38

Ref: 7W-GP3703

Zearalanone

CAS: 5975-78-0

Zearalanone

Molecular weight: 320.38016g/mol

Ref: 54-BI12147

Zearalanone 10 µg/mL in Acetonitrile

Controlled Product

CAS: 5975-78-0

Formula: C₁₈H₂₄O₅

Color and Shape: Single Solution

Molecular weight: 320.38

Ref: 04-A17947350AL-10

Zearalanone

CAS: 5975-78-0

Formula: C₁₈H₂₄O₅

Color and Shape: Neat

Molecular weight: 320.38

Ref: 04-C17947350

Fusarium Toxins Mixture 10-100 µg/mL in Acetonitrile

Controlled Product

CAS: 17924-92-4, 21259-20-1, 26934-87-2, 51481-10-8, 5975-78-0

Color and Shape: Mixture

Ref: 04-V30000007AL

A + B-Trichothecenes and Zearalenone Mixture 10 µg/mL in Acetonitrile

Controlled Product

CAS: 17924-92-4, 21259-20-1, 2270-40-8, 23255-69-8, 23282-20-4, 26934-87-2, 50722-38-8, 51481-10-8, 5975-78-0

Color and Shape: Mixture

Ref: 04-V30000004AL

Zearalanone

CAS: 5975-78-0

Zearalenone is a nonsteroidal estrogenic mycotoxin produced by Fusarium species, which colonizes several grains.

Formula: C₁₈H₂₄O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 320.38

Ref: TM-T13391

(S)-Zearalanone

Controlled Product

CAS: 5975-78-0

Applications A secondary metabolite of Zearalenone (ZON). The macrocyclic lactone Zearalanone used in the synthesis of d,l-Zearalanol.
References Hurd, R.N., et al.: J. Med. Chem., 16(5), 543 (1973), Baughman, R., et al.: Science, 297, 787 (2002), Zinedine, A., et al.: Food Chem. Toxicol., 45, 1 (2007), Chailapakul, O., et al.: Food Chem., 109, 876 (2008),

Formula: C₁₈H₂₄O₅

Color and Shape: White To Off-White

Molecular weight: 320.38

Ref: TR-Z270450

Zearalanone

CAS: 5975-78-0

Zearalanone is a mycotoxin that is produced by certain species of the Fusarium fungi. This compound is structurally related to the known mycotoxin zearalenone, and it exhibits similar functionalities. It is primarily found in grains such as maize, barley, oats, wheat, and rice that have been contaminated by these fungi. The mode of action of zearalanone involves its mimicry of estrogenic activity. It binds to estrogen receptors in various tissues, disrupting normal endocrine functions. This disruption can have significant implications in both human and animal health, leading to reproductive issues and developmental anomalies.

Purity: Min. 95%

Ref: 3D-BZ162752