CAS: 59865-13-3 - Cyclosporine A

Formula: C₆₂H₁₁₁N₁₁O₁₂

InChI: InChI=1/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50+,51+,52-/m1/s1

Synonyms:

• Cyclosporina
• Cyclosporine
• Cyclosporin
• Restasis
• cyclosporin A
• Antibiotic S 7481F1
• 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-3,21-bis(1-methylethyl)-6,9,18,24-tetrakis(2-methylpropyl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
• (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-3,21-bis(1-methylethyl)-6,9,18,24-tetrakis(2-methylpropyl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
• 1: PN: US6686454 SEQID: 1 claimed protein
• 7: PN: WO0002548 PAGE: 30 claimed protein
• Arpimune ME
• Cicloral
• Cicloral (antibiotic)
• Ciclosporin
• Cipol N
• Consupren
• Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]
• Debio088
• Equoral
• Gengraf
• Neoplanta
• Neoral
• Nsc 290193
• Ol 27-400
• Papilock Mini
• Ramihyphin A
• Sandimmun
• Sandimmune
• Sandimmune Neoral
• Sang-35
• SangCyA
• Sdz-Oxl 400
• Sigmasporin Microoral
• S-Neoral
• Zinograf ME
• Sandimmun Neoral

Cyclosporin A, 99+%

CAS: 59865-13-3

Ciclosporin A induces apoptosis and inhibits angiogenesis induced by VEGF. It also suppresses the replication …

• Formula: C₆₂H₁₁₁N₁₁O₁₂
• Purity: 99+%
• Color and Shape: White, Powder or crystals or crystalline powder
• Molecular weight: 1202.61

Cyclosporin A, 98%

CAS: 59865-13-3

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Purity: 98%
• Color and Shape: White to almost white, Powder or crystalline powder

Ciclosporin CRS

CAS: 59865-13-3

Cyclosporine

CAS: 59865-13-3

Lactams, nesoi

• Formula: C₆₂H₁₁₁N₁₁O₁₂
• Color and Shape: White Powder
• Molecular weight: 1201.84137

Cyclosporin A

CAS: 59865-13-3

Cyclosporin A is a Calcineurin Inhibitor Immunosuppressant, and a Cytochrome P450 3A4 Inhibitor, and P-Glycoprotein …

• Formula: C₆₂H₁₁₁N₁₁O₁₂
• Purity: 99.85% - 99.99%
• Color and Shape: White Powder
• Molecular weight: 1202.61

Cyclosporin A

CAS: 59865-13-3

• Formula: C₆₁H₁₀₉N₁₁O₁₂
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 1188.5847

Cyclosporin A-13C2-d4 (Cyclosporine-13C2-d4)

CAS: 59865-13-3

• Formula: C₆₀₁₃C₂H₁₀₇D₄N₁₁O₁₂
• Molecular weight: 1208.64

Cyclosporin A

CAS: 59865-13-3

• Formula: C₆₂H₁₁₁N₁₁O₁₂
• Purity: 98.5 - 101.5 % (dried basis)
• Color and Shape: Colourless crystals, or white to almost white powder
• Molecular weight: 1202.61

Cyclosporin A, USP grade

CAS: 59865-13-3

• Formula: C₆₂H₁₁₁N₁₁O₁₂
• Purity: ≤ 0.7%
• Color and Shape: Colourless crystals, or white to almost white powder
• Molecular weight: 1202.61

Cyclosporin A (Cyclosporine)

CAS: 59865-13-3

• Formula: C₆₂H₁₁₁N₁₁O₁₂
• Color and Shape: White To Off-White Solid
• Molecular weight: 1202.64

Cyclosporin A

CAS: 59865-13-3

• Formula: C₆₂H₁₁₁N₁₁O₁₂
• Color and Shape: Neat
• Molecular weight: 1202.61

Ciclosporin

CAS: 59865-13-3

• Formula: C₆₂H₁₁₁N₁₁O₁₂
• Color and Shape: Neat
• Molecular weight: 1202.61

Cyclosporin A

CAS: 59865-13-3

• Formula: C₆₂H₁₁₁N₁₁O₁₂
• Purity: >97.0%(HPLC)(N)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 1,202.64

Cyclosporin A

CAS: 59865-13-3

• Formula: C₆₂H₁₁₁N₁₁O₁₂
• Purity: 95%~99%
• Molecular weight: 1202.64

Cyclosporine A-d4

CAS: 59865-13-3

• Formula: C₆₂H₁₀₇N₁₁O₁₂D₄
• Molecular weight: 1206.67

Cyclosporine A from Beauveria nlyea

CAS: 59865-13-3

• Purity: 99%
• Color and Shape: White Solid
• Molecular weight: 1,202.61g/mol

Cyclosporin A from Tolypocladium inflatum

CAS: 59865-13-3

• Formula: C₆₂H₁₁₁N₁₁O₁₂
• Purity: By hplc: >99% (Typical Value in Batch COA)
• Color and Shape: white solid
• Molecular weight: 1,202.61g/mol

Cyclosporin A

CAS: 59865-13-3

• Purity: 97%
• Molecular weight: 1,202.62g/mol

Ciclosporin RS

CAS: 59865-13-3

• Color and Shape: White Solid Powder

Cyclosporin A-d4 (Major)

CAS: 59865-13-3

Applications An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of …

• Formula: C₆₂H₁₀₇D₄N₁₁O₁₂
• Color and Shape: White To Light Yellow
• Molecular weight: 1206.66