CAS 59870-68-7
:Glabridin
Description:
Glabridin is a natural compound primarily found in the roots of Glycyrrhiza glabra, commonly known as licorice. It belongs to the class of flavonoids and is recognized for its various biological activities. Glabridin exhibits antioxidant properties, which help in neutralizing free radicals and reducing oxidative stress. Additionally, it has been studied for its potential anti-inflammatory effects and its ability to inhibit the enzyme tyrosinase, making it of interest in skin whitening applications. The compound is also noted for its potential neuroprotective effects and its role in modulating metabolic processes. Glabridin is typically characterized by its pale yellow color and is soluble in organic solvents, while being less soluble in water. Its safety profile has been evaluated, and it is generally considered safe for use in cosmetic formulations. However, as with any bioactive compound, further research is necessary to fully understand its mechanisms of action and potential therapeutic applications.
Formula:C20H20O4
InChI:InChI=1S/C20H20O4/c1-20(2)8-7-16-18(24-20)6-3-12-9-13(11-23-19(12)16)15-5-4-14(21)10-17(15)22/h3-8,10,13,21-22H,9,11H2,1-2H3/t13-/m0/s1
InChI key:InChIKey=LBQIJVLKGVZRIW-ZDUSSCGKSA-N
SMILES:CC1(C)OC2=C(C3=C(C[C@@H](CO3)C4=C(O)C=C(O)C=C4)C=C2)C=C1
Synonyms:- 1,3-Benzenediol, 4-(3,4-dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-3-yl)-, (R)-
- 1,3-Benzenediol, 4-[(3R)-3,4-dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-3-yl]-
- 2H,8H-Benzo[1,2-b:3,4-b′]dipyran, 1,3-benzenediol deriv.
- 4-[(3R)-3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-3-yl]-1,3-benzenediol
- 4-[(3R)-8,8-Dimethyl-3,4-dihydro-2H-pyrano[6,5-f]chromen-3-yl]benzene-1,3-diol
- 4-[(3R)-8,8-dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol
- Glabridin
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Glabridin
CAS:Formula:C20H20O4Purity:>98.0%(GC)Color and Shape:White to Light yellow powder to crystalMolecular weight:324.38Glabridin
CAS:Glabridin analytical standard provided with w/w absolute assay, to be used for quantitative titration.Formula:C20H20O4Purity:(HPLC) ≥98%Color and Shape:PowderMolecular weight:324.38Glabridin (Standard)
CAS:Glabridin (Standard) is a reference standard for research and analysis in studies involving Glabridin. Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels; may possess a therapeutic effect on metabolic disorders( such as diabetes and hyperglycemia), by modulating glucose metabolism through AMPK in skeletal muscle cells. Glabridin may have potential as a chemopreventive agent against liver Y metastasis, by inhibiting the invasion of human HCC cells.Formula:C20H20O4Molecular weight:324.3704Glabridin
CAS:Applications Glabridin is a compound extracted from Licorice (root) shows properties that are cytotoxic, antimicrobial, estrogenic and anti-proliferative.
References Tian, M. et al.: Int. J. Mol. Sci., 9, 571 (2008); Simmler, C. et al.: Fitoterapia, 90, 160 (2013);Formula:C20H20O4Color and Shape:NeatMolecular weight:324.37Glabridin
CAS:Formula:C20H20O4Purity:≥ 98.0%Color and Shape:White, off-white or pale yellow-brown powderMolecular weight:324.37Glabridin
CAS:(R)-4-(8,8-Dimethyl-2,3,4,8-tetrahydropyrano[2,3-f]chromen-3-yl)benzene-1,3-diolFormula:C20H20O4Purity:97%Molecular weight:324.37Glabridin
CAS:Glabridin aids in diabetes by reducing inflammation and glucose levels and may prevent liver cancer spread.Formula:C20H20O4Purity:99.78% - 99.93%Color and Shape:Light Yellow Powder Insoluble In WaterMolecular weight:324.3704Glabridin
CAS:Oxygen-heterocyclic compoundFormula:C20H20O4Purity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:324.38Glabridin - Bio-X ™
CAS:This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formula:C20H20O4Purity:Min. 95%Color and Shape:PowderMolecular weight:324.37 g/molGlabridin
CAS:Glabridin is a flavonoid compound, which is primarily isolated from the root of the licorice plant, Glycyrrhiza glabra. It functions as a potent skin-lightening and anti-inflammatory agent through its ability to inhibit melanin synthesis in the skin. This mode of action is primarily achieved by inhibiting the activity of tyrosinase, an enzyme crucial in the melanin biosynthesis pathway. Additionally, Glabridin exhibits antioxidant properties, which help to protect skin cells from oxidative damage.Formula:C20H20O4Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:324.37 g/mol
