CAS 60-27-5

Creatinine

Description:

Creatinine is a nitrogenous organic compound with the chemical formula C4H7N3O, primarily produced from muscle metabolism. It is a byproduct of creatine phosphate, which plays a crucial role in energy production in muscle cells. Creatinine is typically found in blood and urine, and its levels are commonly used as an indicator of kidney function. The substance is a white, crystalline powder that is soluble in water and has a slightly alkaline pH. Its molecular weight is approximately 113.12 g/mol. Creatinine is stable under normal conditions but can undergo degradation under extreme pH or temperature. In clinical settings, measuring creatinine levels helps assess renal health, as elevated levels may indicate impaired kidney function or other medical conditions. Additionally, creatinine clearance tests are often performed to evaluate glomerular filtration rate (GFR), providing insight into kidney performance. Overall, creatinine serves as an important biomarker in both clinical and physiological studies.

Formula: C₄H₇N₃O

InChI: InChI=1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8)

InChI key: InChIKey=DDRJAANPRJIHGJ-UHFFFAOYSA-N

SMILES: NC=1N(C)CC(=O)N1

Synonyms:

• 1-Methylglycocyamidine
• 1-Methylhydantoin-2-imide
• 2-Amino-1,5-dihydro-1-methyl-4H-imidazol-4-one
• 2-Amino-1-methyl-1,5-dihydroimidazol-4-one
• 2-Amino-1-methyl-4,5-dihydro-1H-imidazol-4-one
• 2-Amino-1-methylimidazolidin-4-one
• 2-Amino-1-methylimidazolin-4-one
• 2-Imino-1-Methylimidazolidine-4-One
• 2-Imino-1-Metilimidazolidin-4-Ona
• 2-Imino-1-methyl-imidazolidin-4-one
• 2-Imino-1-methylimidazolidin-4-on
• 2-Imino-1-methylimidazolidin-4-one
• 2-amino-1-methyl-1,5-dihydro-4H-imidazol-4-one
• 2-amino-3-methyl-5-oxo-4,5-dihydro-1H-imidazol-3-ium
• 4H-Imidazol-4-one, 2-amino-1,5-dihydro-1-methyl-
• Kreatinine
• Nsc 13123
• TEGO Cosmo C 250

Creatinine

CAS: 60-27-5

Formula: C₄H₇N₃O

Purity: >99.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 113.12

Ref: 3B-C0398

Creatinine, 98%

CAS: 60-27-5

Creatinine levels in blood and urine may be used to calculate the creatinine clearance (CrCl), which reflects the glomerular filtration rate (GFR), an important clinical index of renal function. It is a substrate for creatininase. This Thermo Scientific Chemicals brand product was originally part of

Formula: C₄H₇N₃O

Purity: 98%

Color and Shape: White, Crystals or powder or crystalline powder

Molecular weight: 113.12

Ref: 02-B23097

Creatinine (2-Imino-1-methylimidazolidin-4-one)

CAS: 60-27-5

Compounds containing an unfused imidazole ring, whether or not hydrogenated, in the structure, nesoi

Formula: C₄H₇N₃O

Color and Shape: White Off-White Crystalline Powder

Molecular weight: 113.05891

Ref: 45-1150353

Creatinine

CAS: 60-27-5

Formula: C₄H₇N₃O

Purity: 98%

Color and Shape: Solid

Molecular weight: 113.1179

Ref: IN-DA003P2T

Creatinine

CAS: 60-27-5

Creatinine (NSC-13123), a creatine byproduct from muscles, is excreted by kidneys; its serum level indicates renal function.

Formula: C₄H₇N₃O

Purity: 97.20% - 99.36%

Color and Shape: Colourless Solid Powder

Molecular weight: 113.12

Ref: TM-T0496

Creatinine

CAS: 60-27-5

Creatinine

Purity: ≥95%

Molecular weight: 113.12g/mol

Ref: 54-BUP18477

Creatinine-13C-d3

CAS: 60-27-5

Formula: C₃₁₃CH₄D₃N₃O

Molecular weight: 117.13

Ref: 4Z-C-292

Creatinine

CAS: 60-27-5

Formula: C₄H₇N₃O

Purity: 98.0 - 102.0 % (dried basis)

Color and Shape: White to almost white crystalline powder

Molecular weight: 113.12

Ref: 7W-GK8780

Creatinine

CAS: 60-27-5

Formula: C₄H₇N₃O

Color and Shape: White To Off-White Solid

Molecular weight: 113.12

Ref: 4Z-C-294

Creatine-d5 (N-methyl-d3 ;imidazolidinone-5,5-d2)

CAS: 60-27-5

Purity: 99 atom % D

Molecular weight: 118.15

Ref: 3U-D7707

2-Amino-3-methyl-4H-imidazol-5-one

CAS: 60-27-5

2-Amino-3-methyl-4H-imidazol-5-one

Formula: C₄H₇N₃O

Purity: 97%

Color and Shape: white solid

Molecular weight: 113.12g/mol

Ref: 54-OR905165

Creatinine

CAS: 60-27-5

Stability Light Sensitive
Applications Creatinine is the end product of creatine catabolism. Creatinine is a normal constituent of urine. Also found together with creatine in muscle tissues and blood. Creatinine is found in all soils and in grain seeds and other vegetable matter as well as in certain fish and in crab meat extract.
References Folin, et al.: J. Biol. Chem., 17, 463 (1914);

Formula: C₄H₇N₃O

Color and Shape: Neat

Molecular weight: 113.118

Ref: TR-C781500

Creatinine-d5 (N-methyl-d3; imidazolidinone-5,5-d2)

Controlled Product

CAS: 60-27-5

Formula: C₄D₅H₂N₃O

Color and Shape: Neat

Molecular weight: 118.149

Ref: TR-C781504

Creatinine

CAS: 60-27-5

Creatinine is a normal breakdown product of creatine, which is a natural substance found in the body. Creatinine is used as an indicator of kidney function and is routinely measured in the blood to test for kidney disease. Creatinine levels are often elevated with the use of nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen, but these drugs also increase creatinine values. Creatinine levels are also elevated in people with high body mass index (BMI). Creatinine can be measured in urine or blood serum samples. There are many causes of high creatinine levels, including congestive heart failure, HIV infection, and various cancers.

Formula: C₄H₇N₃O

Color and Shape: White Powder

Molecular weight: 113.12 g/mol

Ref: 3D-FC01718

Creatinine extrapure CHR, 99%

CAS: 60-27-5

Formula: C₄H₇N₃O

Purity: min. 99%

Color and Shape: White, Crystalline powder, Clear, Colourless

Molecular weight: 113.12

Ref: SR-65142

Creatinine for cell culture, 99%, Endotoxin (BET) 0.05EU/mg

CAS: 60-27-5

Formula: C₄H₇N₃O

Purity: min. 99%

Color and Shape: White, Crystalline powder, Clear, Colourless

Molecular weight: 113.12

Ref: SR-15353

Creatinine extrapure AR, 99%

CAS: 60-27-5

Formula: C₄H₇N₃O

Purity: min. 99%

Color and Shape: White, Crystalline Powder, Clear, Colourless

Molecular weight: 113.12

Ref: SR-19428

2-Imino-1-methylimidazolidin-4-one

CAS: 60-27-5

Formula: C₄H₇N₃O

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 113.12

Ref: 10-F240558

2-imino-1-methylimidazolidin-4-one

CAS: 60-27-5

Purity: 98%

Molecular weight: 113.1200027

Ref: 10-F868786

Creatinine - tests performed to USP

CAS: 60-27-5

Creatinine is the end product of creatine, which is a natural substance found in muscle tissue. Creatinine levels are used to measure how well the kidneys are functioning. Creatinine is also a component of total protein and blood urea nitrogen (BUN). Creatinine has been shown to have a positive effect on HIV-infected patients by stimulating the production of colony-stimulating factor, which helps to build up the immune system. Creatinine can be detected in blood samples using an enzyme activity assay or it can be measured using creatinine assays that use skin cells or biological samples. Creatinine levels are also used to diagnose conditions such as kidney dysfunction, liver disease, and heart failure. Creatinine levels may also be used to help predict prognosis for untreated group p2 with glomerular filtration rate (GFR) less than 60ml/min per 1.73m2 body surface area.

Formula: C₄H₇N₃O

Color and Shape: Powder

Molecular weight: 113.12 g/mol

Ref: 3D-FC178344