CAS 60-87-7

(±)-Promethazine

Description:

(±)-Promethazine is a first-generation antihistamine belonging to the phenothiazine class, primarily used for its antihistaminic, antiemetic, and sedative properties. It is characterized by its ability to block H1 histamine receptors, which helps alleviate allergic reactions and symptoms such as itching, runny nose, and sneezing. Additionally, (±)-Promethazine exhibits anticholinergic effects, contributing to its use in preventing motion sickness and as a preoperative sedative. The compound is typically administered in various forms, including tablets, syrups, and injections. Its chemical structure features a phenothiazine backbone, which is responsible for its pharmacological activity. The substance is known for its potential side effects, including drowsiness, dry mouth, and dizziness, and it should be used with caution in certain populations, such as the elderly or those with specific medical conditions. Due to its sedative effects, (±)-Promethazine is often prescribed for short-term management of sleep disturbances or anxiety. Overall, it is a versatile medication with a range of therapeutic applications, but it requires careful monitoring due to its side effect profile.

Formula: C₁₇H₂₀N₂S

InChI: InChI=1S/C17H20N2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3

InChI key: InChIKey=PWWVAXIEGOYWEE-UHFFFAOYSA-N

SMILES: C(C(N(C)C)C)N1C=2C(SC=3C1=CC=CC3)=CC=CC2

Synonyms:

• (.+-.)-Promethazine
• (2-Dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine
• 10-[2-(Dimethylamino)propyl]phenothiazine
• 10H-Phenothiazine-10-ethanamine, N,N,α-trimethyl- (9CI)
• Dimapp
• Diphergan
• N,N,α-Trimethyl-10H-phenothiazine-10-ethanamine
• Nsc 30321
• Phenothiazine, 10-[2-(dimethylamino)propyl]-
• Proazamine
• Procit
• Prometazin
• Prometazina
• Promethazin
• Protazine
• Prothazin
• Rp 3277
• Vallergine
• Promethaine
• 10H-Phenothiazine-10-ethanamine, N,N,α-trimethyl-

Promethazine

CAS: 60-87-7

Promethazine (Proazamine) is an analogue of anti-glaucoma prostaglandin (PG) .

Formula: C₁₇H₂₀N₂S

Purity: 99.76%

Color and Shape: Crystals

Molecular weight: 284.42

Ref: TM-T0445

Promethazine

CAS: 60-87-7

Formula: C₁₇H₂₀N₂S

Color and Shape: Off-White Solid

Molecular weight: 284.42

Ref: 4Z-P-182

Promethazine

CAS: 60-87-7

Promethazine

Purity: ≥98%

Molecular weight: 284.42g/mol

Ref: 54-BUP13591

Promethazine Hydrochloride

CAS: 58-33-3, 60-87-7

Formula: C₁₇H₂₀N₂S·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 320.88

Ref: 3B-P2029

Promethazine

Controlled Product

CAS: 60-87-7

Formula: C₁₇H₂₀N₂S

Color and Shape: Neat

Molecular weight: 284.421

Ref: TR-P014696

Promethazine

Controlled Product

CAS: 60-87-7

Histamine receptor H1 antagonist

Formula: C₁₇H₂₀N₂S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 284.42 g/mol

Ref: 3D-FP35119

Promethazine

CAS: 60-87-7

Formula: C₁₇H₂₀N₂S

Molecular weight: 284.43

Ref: ST-EA-CP-P86000