CAS 60133-18-8
:1α,25-Dihydroxyvitamin D2
Description:
1α,25-Dihydroxyvitamin D2, also known as ergocalciferol, is a biologically active form of vitamin D2, which plays a crucial role in calcium and phosphate metabolism in the body. It is a secosteroid, meaning it has a structure derived from steroids but with a broken ring. This compound is primarily involved in regulating the absorption of calcium and phosphate in the intestines, promoting bone health and mineralization. It is synthesized in the body from ergosterol, a precursor found in fungi and yeast, upon exposure to ultraviolet light. The substance exhibits high affinity for the vitamin D receptor, influencing gene expression related to calcium homeostasis. 1α,25-Dihydroxyvitamin D2 is also important in immune function and has been studied for its potential roles in various diseases, including autoimmune disorders and certain cancers. Its solubility in organic solvents and relatively low solubility in water are notable characteristics, impacting its bioavailability and pharmacokinetics.
Formula:C28H44O3
InChI:InChI=1S/C28H44O3/c1-18(9-10-19(2)27(4,5)31)24-13-14-25-21(8-7-15-28(24,25)6)11-12-22-16-23(29)17-26(30)20(22)3/h9-12,18-19,23-26,29-31H,3,7-8,13-17H2,1-2,4-6H3/b10-9+,21-11+,22-12-/t18-,19+,23-,24-,25+,26+,28-/m1/s1
InChI key:InChIKey=ZGLHBRQAEXKACO-XJRQOBMKSA-N
SMILES:C[C@@]12[C@](\C(=C\C=C\3/C(=C)[C@@H](O)C[C@H](O)C3)\CCC1)(CC[C@@]2([C@@H](/C=C/[C@@H](C(C)(C)O)C)C)[H])[H]
Synonyms:- (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol
- (1S,3R,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraene-1,3,25-triol
- 1,25-Dihydroxycalciferol
- 1,25-Dihydroxyergocalciferol
- 1,25-Dihydroxyvitamin D<sub>2</sub>
- 1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)-
- 1alpha,25-Dihydroxycalciferol
- 1α,25-Dihydroxycalciferol
- 1α,25-Dihydroxyergocalciferol
- 1α,25-Dihydroxyvitamin D<sub>2</sub>
- 9,10-Secoergosta-5,7,10(19),22-tetraene-1,3,25-triol, (1α,3β,5Z,7E,22E)-
- Ercalcitriol
- Ro 17-6218
- See more synonyms
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Found 7 products.
1α,25-Dihydroxyvitamin D2
CAS:Formula:C28H44O3Purity:≥ 95.0%Color and Shape:White crystalline powderMolecular weight:428.65Ercalcitriol
CAS:<p>Ercalcitriol, active Vitamin D2 metabolite, boosts immunity by regulating CAMP and DEFB4 genes against infections.</p>Formula:C28H44O3Purity:99.02%Color and Shape:SolidMolecular weight:428.651α,25-Dihydroxy Vitamin D2
CAS:Controlled ProductFormula:C28H44O3Color and Shape:NeatMolecular weight:428.651a,25-Dihydroxy vitamin D2
CAS:<p>1a,25-Dihydroxy vitamin D2 is a compound that exhibits various characteristics and applications. It is known for its bioavailability and water-soluble properties, making it easily absorbed by the body. This compound has been extensively studied in the field of research chemicals. One of the notable features of 1a,25-Dihydroxy vitamin D2 is its potential therapeutic effects on ganglioside GM2-related disorders. It has been shown to interact with GM2 activator proteins and fatty acids, which are involved in the metabolism of GM2 gangliosides. This interaction may have implications for the treatment of certain neurological conditions. Additionally, 1a,25-Dihydroxy vitamin D2 has been investigated for its role in modulating immune responses and inflammatory processes. Studies have suggested that this compound can inhibit the production of pro-inflammatory substances like prostaglandins, offering potential anti-inflammatory benefits. Moreover, 1a,25-Dihydroxy vitamin D</p>Formula:C28H44O3Purity:Min. 95%Color and Shape:White PowderMolecular weight:428.65 g/mol
