CAS 60133-18-8

1α,25-Dihydroxyvitamin D2

Description:

1α,25-Dihydroxyvitamin D2, also known as ergocalciferol, is a biologically active form of vitamin D2, which plays a crucial role in calcium and phosphate metabolism in the body. It is a secosteroid, meaning it has a structure derived from steroids but with a broken ring. This compound is primarily involved in regulating the absorption of calcium and phosphate in the intestines, promoting bone health and mineralization. It is synthesized in the body from ergosterol, a precursor found in fungi and yeast, upon exposure to ultraviolet light. The substance exhibits high affinity for the vitamin D receptor, influencing gene expression related to calcium homeostasis. 1α,25-Dihydroxyvitamin D2 is also important in immune function and has been studied for its potential roles in various diseases, including autoimmune disorders and certain cancers. Its solubility in organic solvents and relatively low solubility in water are notable characteristics, impacting its bioavailability and pharmacokinetics.

Formula: C₂₈H₄₄O₃

InChI: InChI=1S/C28H44O3/c1-18(9-10-19(2)27(4,5)31)24-13-14-25-21(8-7-15-28(24,25)6)11-12-22-16-23(29)17-26(30)20(22)3/h9-12,18-19,23-26,29-31H,3,7-8,13-17H2,1-2,4-6H3/b10-9+,21-11+,22-12-/t18-,19+,23-,24-,25+,26+,28-/m1/s1

InChI key: InChIKey=ZGLHBRQAEXKACO-XJRQOBMKSA-N

SMILES: C[C@@]12[C@](\C(=C\C=C\3/C(=C)[C@@H](O)C[C@H](O)C3)\CCC1)(CC[C@@]2([C@@H](/C=C/[C@@H](C(C)(C)O)C)C)[H])[H]

Synonyms:

• (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol
• (1S,3R,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraene-1,3,25-triol
• 1,25-Dihydroxycalciferol
• 1,25-Dihydroxyergocalciferol
• 1,25-Dihydroxyvitamin D₂
• 1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)-
• 1alpha,25-Dihydroxycalciferol
• 1α,25-Dihydroxycalciferol
• 1α,25-Dihydroxyergocalciferol
• 1α,25-Dihydroxyvitamin D₂
• 9,10-Secoergosta-5,7,10(19),22-tetraene-1,3,25-triol, (1α,3β,5Z,7E,22E)-
• Ercalcitriol
• Ro 17-6218

1α,25-Dihydroxyvitamin D2

CAS: 60133-18-8

Formula: C₂₈H₄₄O₃

Purity: ≥ 95.0%

Color and Shape: White crystalline powder

Molecular weight: 428.65

Ref: 7W-GV4313

Ercalcitriol

CAS: 60133-18-8

Ercalcitriol, active Vitamin D2 metabolite, boosts immunity by regulating CAMP and DEFB4 genes against infections.

Formula: C₂₈H₄₄O₃

Purity: 99.02%

Color and Shape: Solid

Molecular weight: 428.65

Ref: TM-TQ0216

Ercalcitriol

CAS: 60133-18-8

Ercalcitriol

Formula: C₂₈H₄₄O₃

Purity: ≥98%

Molecular weight: 428.65

Ref: 54-BUP01433

1.25-Dihydroxyvitamin D2 in Ethanol, Concentration: 50 µg/mL (Standard)

CAS: 60133-18-8

Ercalcitriol (Standard) is a reference standard for research and analysis in studies involving Ercalcitriol. Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is an active metabolite of vitamin D2. Ercalcitriol, as the physiological activated form of vitamin D, can strengthen immunity via regulation of cathelicidin antimicrobial peptide (CAMP) and defensin β-4 (DEFB4) genes in normal and transformed cells to combat pathogenic infections.

Formula: C₂₈H₄₄O₃

Color and Shape: Solid

Molecular weight: 428.65

Ref: TM-TMSM-3162

25-Hydroxy Doxercalciferol

CAS: 60133-18-8

Formula: C₂₈H₄₄O₃

Molecular weight: 428.66

Ref: 4Z-V-081

1α,25-Dihydroxy Vitamin D2

Controlled Product

CAS: 60133-18-8

Formula: C₂₈H₄₄O₃

Color and Shape: Neat

Molecular weight: 428.65

Ref: TR-D455065

1,25-Dihydroxyvitamin D2 in Ethanol

CAS: 60133-18-8

Ethanol

Ref: BE-MU-0095XF-100

1.25-Dihyroxyvitamin D2-[13C3] in Ethanol

CAS: 60133-18-8

Ethanol

Ref: BE-MC-0095A5F-5

1.25-Dihydroxyvitamin D2 in Ethanol

CAS: 60133-18-8

Ethanol

Ref: BE-MU-0095MF-50

1.25-Dihydroxyvitamin D2-[13C5]

CAS: 60133-18-8

Ref: BE-MC-0095C5

1,25-Dihydroxyvitamin D2-[13C3]

CAS: 60133-18-8

Ref: BE-MC-0095

1,25-Dihydroxyvitamin D2

CAS: 60133-18-8

Ref: BE-MU-0095

Ercalcitriol

CAS: 60133-18-8

Ref: BE-RMCV080001

1.25-Dihydroxyvitamin D2-[13C3] in Ethanol

CAS: 60133-18-8

Ethanol

Ref: BE-MC-0095MF-50

1.25-Dihydroxyvitamin D2-[13C3] in Ethanol

CAS: 60133-18-8

Ethanol

Ref: BE-MC-0095LF-10

1.25-Dihydroxyvitamin D2-[13C3] in Ethanol

CAS: 60133-18-8

Ethanol

Ref: BE-MC-0095XF-100

1.25-Dihydroxyvitamin D2-[13C5] in Ethanol

CAS: 60133-18-8

Ethanol

Ref: BE-MC-0095C5MF-50

1.25-Dihydroxyvitamin D2-[13C5] in Ethanol

CAS: 60133-18-8

Ethanol

Ref: BE-MC-0095C5XF-100

1.25-Dihydroxyvitamin D2-[13C5] in Ethanol

CAS: 60133-18-8

Ethanol

Ref: BE-MC-0095C5LF-10

1a,25-Dihydroxy vitamin D2

CAS: 60133-18-8

1a,25-Dihydroxy vitamin D2 is a compound that exhibits various characteristics and applications. It is known for its bioavailability and water-soluble properties, making it easily absorbed by the body. This compound has been extensively studied in the field of research chemicals. One of the notable features of 1a,25-Dihydroxy vitamin D2 is its potential therapeutic effects on ganglioside GM2-related disorders. It has been shown to interact with GM2 activator proteins and fatty acids, which are involved in the metabolism of GM2 gangliosides. This interaction may have implications for the treatment of certain neurological conditions. Additionally, 1a,25-Dihydroxy vitamin D2 has been investigated for its role in modulating immune responses and inflammatory processes. Studies have suggested that this compound can inhibit the production of pro-inflammatory substances like prostaglandins, offering potential anti-inflammatory benefits. Moreover, 1a,25-Dihydroxy vitamin D

Formula: C₂₈H₄₄O₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 428.65 g/mol

Ref: 3D-FD22066