CAS 602-41-5
:Thiocolchicoside
Description:
Thiocolchicoside is a chemical compound that belongs to the class of thiosemicarbazones and is derived from colchicine. It is primarily known for its muscle relaxant and anti-inflammatory properties, making it useful in the treatment of various musculoskeletal disorders. The compound exhibits a unique structure characterized by a thioether group, which contributes to its pharmacological activity. Thiocolchicoside is often administered in the form of oral tablets or injections and is recognized for its ability to alleviate pain and improve mobility in patients with muscle spasms. Additionally, it has been studied for its potential neuroprotective effects. The compound is generally well-tolerated, but like any medication, it may have side effects, including gastrointestinal disturbances or allergic reactions in some individuals. Its mechanism of action involves modulation of neurotransmitter release and inhibition of inflammatory mediators, which underscores its therapeutic relevance in clinical settings. As with any pharmaceutical agent, proper dosage and medical supervision are essential to ensure safety and efficacy.
Formula:C27H33NO10S
InChI:InChI=1S/C27H33NO10S/c1-12(30)28-16-7-5-13-9-18(37-27-24(34)23(33)22(32)19(11-29)38-27)25(35-2)26(36-3)21(13)14-6-8-20(39-4)17(31)10-15(14)16/h6,8-10,16,19,22-24,27,29,32-34H,5,7,11H2,1-4H3,(H,28,30)/t16-,19+,22+,23-,24+,27+/m0/s1
InChI key:InChIKey=LEQAKWQJCITZNK-AXHKHJLKSA-N
SMILES:O(C)C1=C2C=3C([C@@H](NC(C)=O)CCC2=CC(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)=C1OC)=CC(=O)C(SC)=CC3
Synonyms:- 10-Thiocolchicoside
- 2-10-Di(demethoxy)-2-glucosyloxy-10-methylthiocolchicine
- 2-Demethoxy-2-glucosidoxythiocolchicine
- Acetamide, N-(3-(beta-D-glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo(a)heptalen-7-yl)-, (S)-
- Acetamide, N-[(7S)-3-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]-
- Acetamide, N-[3-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]-, (S)-
- Benzo[a]heptalene, acetamide deriv.
- Brn 0072205
- Colchicoside, 10-thio-
- Colchicoside, 10-thio- (8CI)
- Colchicoside, thio-
- Coltramyl
- Coltrax
- Etoshine MR
- Miorel
- Miotens
- Musco-ril
- Muscoril
- N-[(7S)-3-(beta-D-glucopyranosyloxy)-1,2-dimethoxy-10-(methylsulfanyl)-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide
- N-[(7S)-3-(β-<span class="text-smallcaps">D</span>-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]acetamide
- N-[3-(beta-D-glucopyranosyloxy)-1,2-dimethoxy-10-(methylsulfanyl)-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide
- N-[3-(hexopyranosyloxy)-1,2-dimethoxy-10-(methylsulfanyl)-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide
- Nsc 147755
- R. 271
- Thiocholshikoside
- Thiocolchicine 2-glucoside analog
- Thiocolchicoside [INN:DCF]
- Thiocolchicosidum
- Thiocolchicosidum [INN-Latin]
- Tiocolchicoside
- Tiocolchicoside [DCIT]
- Tiocolchicosido
- Tiocolchicosido [INN-Spanish]
- Unii-T1X8S697Gt
- Acetamide, N-[(7S)-3-(β-D-glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]-
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Found 18 products.
Thiocolchicoside
CAS:Formula:C27H33NO10SPurity:>98.0%(HPLC)Color and Shape:Light orange to Yellow to Green powder to crystalMolecular weight:563.62THIOCOLCHICOSIDE FOR SYSTEM SUITABILITY CRS
CAS:THIOCOLCHICOSIDE FOR SYSTEM SUITABILITY CRSFormula:C27H33NO10SColor and Shape:Yellow. Crystalline Powder., Yellow. Crystalline Powder.Molecular weight:563.6166THIOCOLCHICOSIDE HYDRATE CRS
CAS:THIOCOLCHICOSIDE HYDRATE CRSFormula:C27H33NO10SColor and Shape:Yellow. Crystalline Powder.Molecular weight:563.6166THIOCOLCHICOSIDE CRYSTALLISED FROM ETHANOL CRS
CAS:THIOCOLCHICOSIDE CRYSTALLISED FROM ETHANOL CRSFormula:C27H33NO10SColor and Shape:Yellow. Crystalline Powder., Yellow. Crystalline Powder.Molecular weight:563.6166Thiocolchicoside-13C-d3
CAS:Formula:CC26H30D3NO10SColor and Shape:Yellow SolidMolecular weight:567.63Thiocolchicoside
CAS:Controlled ProductFormula:C27H33NO10SColor and Shape:NeatMolecular weight:563.62Thiocolchicoside
CAS:Formula:C27H33NO10SPurity:(dried basis) 98.0 - 102.0 %Color and Shape:Yellow crystalline powderMolecular weight:563.6Thiocolchicoside
CAS:<p>Thiocolchicoside, a muscle relaxant, has anti-inflammatory and analgesic properties; not for seizure-prone people.</p>Formula:C27H33NO10SPurity:99.11% - 99.39%Color and Shape:SolidMolecular weight:563.62Thiocolchicoside
CAS:Controlled Product<p>Applications A GABA receptor antagonist which is prescribed as a muscle relaxant having analgesic effects.<br>References Gelmi, M., et al.: J. Med. Chem., 50, 2245 (2007), Mascia, M., et al.: Eur. J. Pharmacol., 558, 37 (2007), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),<br></p>Formula:C27H33NO10SColor and Shape:NeatMolecular weight:563.62Thiocolchicoside
CAS:<p>Thiocolchicoside is a non-steroidal anti-inflammatory drug that belongs to the group of drugs known as p2. It has been shown to have statistically significant analgesic effects in animal models of pain. Thiocolchicoside is used to treat acute and chronic pain, especially in those cases where the pain is not relieved by other types of treatment. It has also been used for the treatment of muscle spasms.</p>Formula:C27H33NO10SPurity:Min. 95%Color and Shape:Yellow PowderMolecular weight:563.62 g/molThiocolchicoside extrapure, 98%
CAS:Formula:C27H33NO10SPurity:min. 98%Color and Shape:Yellow to pale orange to green, Powder/CrystalsMolecular weight:563.62Thiocolchicoside-d3
CAS:Controlled Product<p>Applications A labelled GABA receptor antagonist which is prescribed as a muscle relaxant having analgesic effects.<br>References Gelmi, M., et al.: J. Med. Chem., 50, 2245 (2007), Mascia, M., et al.: Eur. J. Pharmacol., 558, 37 (2007), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),<br></p>Formula:C27D3H30NO10SColor and Shape:NeatMolecular weight:566.635
