CAS 60282-87-3

Gestodene

Description:

Gestodene is a synthetic progestin, primarily used in hormonal contraceptives and hormone replacement therapy. It is characterized by its ability to mimic the effects of natural progesterone, thereby influencing the menstrual cycle and maintaining pregnancy. Gestodene is known for its high potency and selectivity for progesterone receptors, which allows it to effectively inhibit ovulation and alter the uterine lining. The substance is typically administered in combination with estrogen in oral contraceptive formulations. Its chemical structure features a steroid backbone, which is common among progestins, and it exhibits a relatively low androgenic activity compared to other progestins, making it a preferred choice for minimizing side effects related to androgenic activity. Gestodene is well-absorbed when taken orally and has a favorable pharmacokinetic profile, contributing to its effectiveness in contraceptive applications. As with any hormonal medication, potential side effects may include changes in mood, weight fluctuations, and alterations in menstrual patterns, necessitating careful consideration and monitoring by healthcare providers.

Formula: C₂₁H₃₂O

InChI: InChI=1/C21H26O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,10,12-13,16-19,23H,3,5-9,11H2,1H3/t16-,17+,18+,19-,20-,21-/m0/s1

InChI key: InChIKey=SIGSPDASOTUPFS-XUDSTZEESA-N

SMILES: C(C)[C@@]12[C@]([C@]3([C@](CC1)([C@@]4(C(CC3)=CC(=O)CC4)[H])[H])[H])(C=C[C@]2(C#C)O)[H]

Synonyms:

• (17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)
• (17α)-13-Ethyl-17-hydroxy-18,19-dinorpregna-4,15-dien-20-yn-3-one
• (8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)
• 13-Ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)
• 18,19-Dinorpregna-4,15-dien-20-yn-3-one, 13-ethyl-17-hydroxy-, (17α)-
• Gestinol
• Shb 331
• Wl 70
• Gestodene
• 15-dien-20-yn-3-one,13-ethyl-17-hydroxy-19-dinorpregna-(17-alpha)-1
• SH B 33
• (17)-13-Ethyl-17-hydroxy-18,19-dinorpregna-4,15-dien-20-yn-3-one
• 17-alpha-ethinyl-13-ethyl-17-beta-hydroxy-4,15-gonadien-3-one
• (8R,9S,10R,13S,14S,17R)-13-Ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14-decahydrocyclopenta[a]phenanthren-3-one
• SH B 331
• 17-alpha-Ethynyl-13-ethyl-17-beta-hydroxy-4,15-gonadien-3-one
• GESTOGENE
• 17α-Ethynyl-17β-hydroxy-18-methylestra-4,15-dien-3-one
• Femodene
• 18,19-Dinorpregna-4,15-dien-20-yn-3-one, 13-ethyl-17-hydroxy-, (17-alpha)
• 17-(2-propenyl)estr-4-en-17-ol
• (17alpha)-13-ethyl-17-hydroxy-18,19-dinorpregna-4,15-dien-20-yn-3-one
• GESTODONE

Gestodene

CAS: 60282-87-3

Formula: C₂₁H₂₆O₂

Purity: >98.0%(HPLC)(qNMR)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 310.44

Ref: 3B-G0404

GESTODENE FOR SYSTEM SUITABILITY CRS

CAS: 60282-87-3

GESTODENE FOR SYSTEM SUITABILITY CRS

Formula: C₂₁H₂₆O₂

Molecular weight: 310.4299

Ref: 41-Y0001110

GESTODENE CRS

CAS: 60282-87-3

GESTODENE CRS

Ref: 41-Y0001112

Gestodene

CAS: 60282-87-3

Gestodene (WL 70) is a progestogen hormonal contraceptive.

Formula: C₂₁H₂₆O₂

Purity: 98% - 99.68%

Color and Shape: White Crystalline Solid

Molecular weight: 310.43

Ref: TM-T1490

Gestoden

CAS: 60282-87-3

Ref: 7W-GP9686

Gestodene

CAS: 60282-87-3

Formula: C₂₁H₂₆O₂

Color and Shape: Off-White Solid

Molecular weight: 310.44

Ref: 4Z-G-191

Gestodene

CAS: 60282-87-3

Gestodene

Purity: ≥98%

Molecular weight: 310.43g/mol

Ref: 54-BUP11756

Gestodene

CAS: 60282-87-3

Gestodene

Purity: 99%

Molecular weight: 310.43g/mol

Ref: 54-OR1025551

Gestodene

CAS: 60282-87-3

Formula: C21H26O2

Purity: >98%

Color and Shape: Solid

Molecular weight: 310.43

Ref: 48-60-1010

Gestodene

Controlled Product

CAS: 60282-87-3

Formula: C₂₁H₂₆O₂

Color and Shape: Neat

Molecular weight: 310.43

Ref: 04-C14012000

Gestodene

CAS: 60282-87-3

Color and Shape: Neat

Ref: 86-MM0124.00

Gestodene-d7

Controlled Product

CAS: 60282-87-3

Formula: C₂₁D₇H₁₉O₂

Color and Shape: Neat

Molecular weight: 317.473

Ref: TR-G368253

Gestodene

CAS: 60282-87-3

Formula: C₂₁H₂₆O₂

Molecular weight: 310.44

Ref: ST-EA-CP-G21000

Gestodene

Controlled Product

CAS: 60282-87-3

Applications Gestodene is an orally active gestogen with a progesterone-like profile of activity. Gestodene is used in combination with estrogen as an oral contraceptive.
References Duesterberg, B., et al.: Contraception, 24, 673 (1981), Duesterberg, B., et al.: Seroids, 43, 43 (1984), Losert, W., et al.: Arzneim.-Forsch., 35, 459 (1985),

Formula: C₂₁H₂₆O₂

Color and Shape: Neat

Molecular weight: 310.43

Ref: TR-G368250

Gestodene - Bio-X ™

Controlled Product

CAS: 60282-87-3

Gestodene is a progestogen hormonal contraceptive. It is an agonist of the progesterone receptor. Additionally, this drug is used in menopausal hormone therapy.

Formula: C₂₁H₂₆O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 310.43 g/mol

Ref: 3D-BG164505

Gestodene

Controlled Product

CAS: 60282-87-3

Synthetic progestin; contraceptive

Formula: C₂₁H₂₆O₂

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 310.43 g/mol

Ref: 3D-FG23660

Gestodene

CAS: 60282-87-3

Formula: C₂₁H₂₆O₂

Purity: 99%(LC-MS);RG

Molecular weight: 310.437

Ref: 10-F462717