CAS 60282-87-3
:Gestodene
Description:
Gestodene is a synthetic progestin, primarily used in hormonal contraceptives and hormone replacement therapy. It is characterized by its ability to mimic the effects of natural progesterone, thereby influencing the menstrual cycle and maintaining pregnancy. Gestodene is known for its high potency and selectivity for progesterone receptors, which allows it to effectively inhibit ovulation and alter the uterine lining. The substance is typically administered in combination with estrogen in oral contraceptive formulations. Its chemical structure features a steroid backbone, which is common among progestins, and it exhibits a relatively low androgenic activity compared to other progestins, making it a preferred choice for minimizing side effects related to androgenic activity. Gestodene is well-absorbed when taken orally and has a favorable pharmacokinetic profile, contributing to its effectiveness in contraceptive applications. As with any hormonal medication, potential side effects may include changes in mood, weight fluctuations, and alterations in menstrual patterns, necessitating careful consideration and monitoring by healthcare providers.
Formula:C21H32O
InChI:InChI=1/C21H26O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,10,12-13,16-19,23H,3,5-9,11H2,1H3/t16-,17+,18+,19-,20-,21-/m0/s1
InChI key:InChIKey=SIGSPDASOTUPFS-XUDSTZEESA-N
SMILES:C(C)[C@@]12[C@]([C@]3([C@](CC1)([C@@]4(C(CC3)=CC(=O)CC4)[H])[H])[H])(C=C[C@]2(C#C)O)[H]
Synonyms:- (17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)
- (17α)-13-Ethyl-17-hydroxy-18,19-dinorpregna-4,15-dien-20-yn-3-one
- (8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)
- 13-Ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)
- 18,19-Dinorpregna-4,15-dien-20-yn-3-one, 13-ethyl-17-hydroxy-, (17α)-
- Gestinol
- Shb 331
- Wl 70
- Gestodene
- 15-dien-20-yn-3-one,13-ethyl-17-hydroxy-19-dinorpregna-(17-alpha)-1
- SH B 33
- (17)-13-Ethyl-17-hydroxy-18,19-dinorpregna-4,15-dien-20-yn-3-one
- 17-alpha-ethinyl-13-ethyl-17-beta-hydroxy-4,15-gonadien-3-one
- (8R,9S,10R,13S,14S,17R)-13-Ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14-decahydrocyclopenta[a]phenanthren-3-one
- SH B 331
- 17-alpha-Ethynyl-13-ethyl-17-beta-hydroxy-4,15-gonadien-3-one
- GESTOGENE
- 17α-Ethynyl-17β-hydroxy-18-methylestra-4,15-dien-3-one
- Femodene
- 18,19-Dinorpregna-4,15-dien-20-yn-3-one, 13-ethyl-17-hydroxy-, (17-alpha)
- 17-(2-propenyl)estr-4-en-17-ol
- (17alpha)-13-ethyl-17-hydroxy-18,19-dinorpregna-4,15-dien-20-yn-3-one
- GESTODONE
- See more synonyms
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Gestodene
CAS:Formula:C21H26O2Purity:>98.0%(HPLC)(qNMR)Color and Shape:White to Almost white powder to crystalMolecular weight:310.44GESTODENE FOR SYSTEM SUITABILITY CRS
CAS:GESTODENE FOR SYSTEM SUITABILITY CRSFormula:C21H26O2Molecular weight:310.4299Gestodene
CAS:Gestodene (WL 70) is a progestogen hormonal contraceptive.Formula:C21H26O2Purity:98% - 99.68%Color and Shape:SolidMolecular weight:310.4299Gestodene
CAS:Controlled ProductApplications Gestodene is an orally active gestogen with a progesterone-like profile of activity. Gestodene is used in combination with estrogen as an oral contraceptive.
References Duesterberg, B., et al.: Contraception, 24, 673 (1981), Duesterberg, B., et al.: Seroids, 43, 43 (1984), Losert, W., et al.: Arzneim.-Forsch., 35, 459 (1985),Formula:C21H26O2Color and Shape:NeatMolecular weight:310.43Gestodene - Bio-X ™
CAS:Controlled ProductGestodene is a progestogen hormonal contraceptive. It is an agonist of the progesterone receptor. Additionally, this drug is used in menopausal hormone therapy.Formula:C21H26O2Purity:Min. 95%Color and Shape:PowderMolecular weight:310.43 g/molGestodene
CAS:Controlled ProductSynthetic progestin; contraceptiveFormula:C21H26O2Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:310.43 g/mol
