
CAS 603113-07-1
:Formula:C21H23N5O3
InChI:InChI=1S/C21H23N5O3/c1-11(8-26-10-25-19(22)18-20(26)24-9-23-18)13-3-4-14-6-15-17(29-16(14)7-13)5-12(2)28-21(15)27/h5-6,9-11,13,16,22H,3-4,7-8H2,1-2H3,(H,23,24)/t11?,13-,16-/m0/s1
InChI key:BHHWUOFZMWUNHA-DKGPUHFJSA-N
SMILES:CC1=CC2=C(C=C3CC[C@@H](C[C@@H]3O2)C(C)CN4C=NC(=N)C5=C4N=CN5)C(=O)O1
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Aβ aggregation-IN-4
CAS:Aβ aggregation-IN-4 reduces the neurotoxicity of β-amyloid protein (Aβ) and significantly decreases the levels of Aβ oligomeric complexes (Aβ-OCs), without affecting the overall levels of Aβ. It mitigates Aβ oligomerization and prevents oligomer-induced death of primary cortical neurons. Aβ aggregation-IN-4 is applicable in Alzheimer's disease (AD) research.Formula:C21H23N5O3Molecular weight:393.45


