CAS 6055-19-2
:Cyclophosphamide monohydrate
Description:
Cyclophosphamide monohydrate is a synthetic alkylating agent primarily used in chemotherapy for various cancers, including lymphomas and leukemias. It is a white to off-white crystalline powder that is soluble in water and has a molecular formula that includes a monohydrate component, indicating the presence of one water molecule per molecule of cyclophosphamide. The substance is characterized by its ability to form DNA cross-links, which inhibit cell division and lead to cell death, making it effective in targeting rapidly dividing cancer cells. Cyclophosphamide is also known for its immunosuppressive properties, which can be beneficial in treating autoimmune disorders. However, it can have significant side effects, including myelosuppression, gastrointestinal disturbances, and potential long-term risks such as secondary malignancies. Proper handling and dosage are crucial due to its cytotoxic nature. As with all chemotherapeutic agents, its use is typically managed by healthcare professionals in a controlled setting.
Formula:C7H15Cl2N2O2P·H2O
InChI:InChI=1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2
InChI key:InChIKey=PWOQRKCAHTVFLB-UHFFFAOYSA-N
SMILES:N(CCCl)(CCCl)P1(=O)NCCCO1.O
Synonyms:- (2R)-N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
- (2S)-N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
- 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide monohydrate
- 2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, hydrate (1:1)
- 2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, monohydrate
- 2H-1,3,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide, monohydrate
- Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester monohydrate
- Cyclophosphamide Isopac Monohydrate
- Cyclophosphamide Sterile monohydrate
- Cyclophosphamide hydrate
- Cyclophosphane monohydrate
- Endoxan monohydrate
- Kgyclophosphamide monohydrate
- N,N-bis(2-chloroethyl)-1-oxo-6-oxa-2-aza-1$l5-phosphacyclohexan-1-amine hydrate
- See more synonyms
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Cyclophosphamide Monohydrate
CAS:Formula:C7H15Cl2N2O2P·H2OPurity:>98.0%(N)Color and Shape:White to Almost white powder to crystalMolecular weight:279.10Cyclophosphamide
CAS:CyclophosphamideFormula:C7H15Cl2N2O2PPurity:93.1%Color and Shape:White Crystalline PowderMolecular weight:260.02482CYCLOPHOSPHAMIDE CRS
CAS:CYCLOPHOSPHAMIDE CRSFormula:C7H17Cl2N2O3PColor and Shape:PowderMolecular weight:279.1012Cyclophosphamide
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C7H15Cl2N2O2P·H2OColor and Shape:White PowderMolecular weight:278.03538Cyclophosphamide hydrate
CAS:Cyclophosphamide hydrateFormula:C7H17Cl2N2O2P·H2OPurity:99.5%Molecular weight:279.1Cyclophosphamide hydrate
CAS:Cyclophosphamide hydrate is a DNA alkylating agent, an inhibitor of DNA synthesis. Cyclophosphamide hydrate has antitumor and immunosuppressive activities.Formula:C7H17Cl2N2O3PPurity:98% - ≥95%Color and Shape:White To Off-White SolidMolecular weight:279.101Cyclophosphamide monohydrate
CAS:Formula:C7H15Cl2N2O2P·H2OPurity:≥ 98.0% (anhydrous basis)Color and Shape:White to off-white crystalline powder or crystalsMolecular weight:279.10Cyclophosphamide Monohydrate
CAS:Cyclophosphamide MonohydrateFormula:C7H15Cl2N2O2P·H2OPurity:>98%Color and Shape:SolidMolecular weight:279.1Cyclophosphamide monohydrate, EP grade
CAS:Formula:C7H15Cl2N2O2P·H2OPurity:(Titration) 98.0 - 102.0 % (anhydrous substance)Color and Shape:White to almost white crystalline powderMolecular weight:279.10Cyclophosphamide hydrate (Standard)
CAS:Cyclophosphamide hydrate (Standard) is a reference standard for research and analysis in studies involving Cyclophosphamide hydrate. Cyclophosphamide hydrate is a synthetic alkylating agent structurally related to nitrogen mustards, with antitumor and immunosuppressive activities. It is widely used in the treatment of various cancers and is also commonly employed to induce animal models of premature ovarian failure, myelosuppression, cystitis, and myocarditis.Formula:C7H17Cl2N2O3PColor and Shape:SolidMolecular weight:279.101Cyclophosphamide Monohydrate
CAS:Controlled ProductFormula:C7H15Cl2N2O2P·H2OColor and Shape:NeatMolecular weight:279.12-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide monohydrate
CAS:Formula:C7H17Cl2N2O3PPurity:97%Color and Shape:SolidMolecular weight:279.1012Cyclophosphamide monohydrate
CAS:Controlled ProductFormula:C7H15Cl2N2O2P·H2OColor and Shape:NeatMolecular weight:279.1Cyclophosphamide Monohydrate
CAS:Controlled ProductApplications It is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This substance is listed as a known human carcinogen.This compound is suitable for aldehyde dehydrogenase (ALDH) related research.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wheeler, A.G., et al.: Toxicol. Appl. Pharmacol., 4, 324 (1962), Fraiser, L.H., et al.: Drugs, 42, 781 (1991), Colvin, O.M., et al.: Curr. Pharmaceut. Design, 5, 555 (1999),Formula:C7H15Cl2N2O2P·H2OColor and Shape:NeatMolecular weight:279.12-(Bis(2-chloroethyl)amino)-1,3,2-oxazaphosphinane 2-oxide hydrate
CAS:2-(Bis(2-chloroethyl)amino)-1,3,2-oxazaphosphinane 2-oxide hydrateFormula:C7H17Cl2N2O3PPurity:98%Molecular weight:279.1Cyclophosphamide monohydrate in Acetonitrile(as free base)
CAS:Acetonitrile（as free base）Formula:C7H17Cl2N2O3PMolecular weight:279.1
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