CAS: 606143-89-9 - 1H-Benzimidazole-6-carboxamide,5-[(4-bromo-2-fluorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-

Formula: C₁₇H₁₅BrF₂N₄O₃

InChI: InChI=1S/C17H15BrF2N4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26)

InChI key: InChIKey=ACWZRVQXLIRSDF-UHFFFAOYSA-N

SMILES: O=C(NOCCO)C1=CC2=C(N=CN2C)C(F)=C1NC3=CC=C(Br)C=C3F

Synonyms:

• 5-[(4-Bromo-2-fluorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide
• Arry 162
• Arry 438162
• Binimetinib
• Mek 162
• Mektovi

Binimetinib (MEK-162)

CAS: 606143-89-9

• Formula: C₁₇H₁₅BrF₂N₄O₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 441.23

Binimetinib

CAS: 606143-89-9

Binimetinib (ARRY-162) (MEK162, ARRY-162, ARRY-438162) is an orally available inhibitor of MEK1/2 (IC50: 12 nM) …

• Formula: C₁₇H₁₅BrF₂N₄O₃
• Purity: 100%
• Color and Shape: Solid
• Molecular weight: 441.23

MEK162

CAS: 606143-89-9

• Formula: C₁₇H₁₅BrF₂N₄O₃
• Purity: 99.55% (lcms) (Typical Value in Batch COA)
• Color and Shape: white to off-white solid
• Molecular weight: 441.23g/mol

MEK 162

CAS: 606143-89-9

Applications MEK 162 is a MEK1/2 inhibitor allowing it to be a effective anti-cancer medication. …

• Formula: C₁₇H₁₅BrF₂N₄O₃
• Color and Shape: White to Off-White Solid
• Molecular weight: 441.23

MEK162

CAS: 606143-89-9

Inhibitor of MEK1/2 kinase enzymes; antineoplastic

• Formula: C₁₇H₁₅BrF₂N₄O₃
• Purity: Min. 95%
• Color and Shape: White/Off-White Solid
• Molecular weight: 441.23 g/mol

N-Desmethyl Binimetinib

CAS: 606143-89-9

• Formula: C₁₆H₁₃BrF₂N₄O₃
• Color and Shape: Off-White to Beige Solid
• Molecular weight: 427.2

MEK 162-13CD3

CAS: 606143-89-9

• Formula: C₁₆CH₁₂D₃BrF₂N₄O₃
• Color and Shape: No data available
• Molecular weight: 445.238

MEK 162-13C, 15N3

CAS: 606143-89-9

Applications MEK 162-13C, 15N3 is the labeled analogue of MEK 162 (M208300), a MEK1/2 inhibitor.

• Formula: C₁₆CH₁₅BrF₂NN₃O₃
• Molecular weight: 445.2