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CAS 606143-89-9

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ARRY 438162

Description:
ARRY 438162, with the CAS number 606143-89-9, is a chemical compound that belongs to the class of small molecule inhibitors. It is primarily recognized for its role as a selective inhibitor of certain kinases, particularly those involved in cancer signaling pathways. The compound exhibits properties that make it a candidate for therapeutic applications, particularly in oncology, by targeting specific molecular mechanisms that drive tumor growth and proliferation. Its structure typically includes functional groups that enhance its binding affinity to target proteins, contributing to its efficacy. Additionally, ARRY 438162 has undergone various preclinical and clinical evaluations to assess its pharmacokinetics, safety profile, and potential side effects. As with many investigational compounds, its characteristics, including solubility, stability, and metabolic pathways, are crucial for understanding its behavior in biological systems and its potential for development into a therapeutic agent.
Formula:C17H15BrF2N4O3
InChI:InChI=1S/C17H15BrF2N4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26)
InChI key:InChIKey=ACWZRVQXLIRSDF-UHFFFAOYSA-N
SMILES:N(C1=C(C(NOCCO)=O)C=C2C(=C1F)N=CN2C)C3=C(F)C=C(Br)C=C3
Synonyms:
  • 5-[(4-Bromo-2-fluorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide
  • Arry 162
  • Arry 438162
  • Binimetinib
  • Mek 162
  • Mektovi
  • 1H-Benzimidazole-6-carboxamide, 5-[(4-bromo-2-fluorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-
  • Binimetinib (MEK-162)
  • 1H-Benzimidazole-6-carboxamide,5-[(4-bromo-2-fluorophenyl)am...
  • 5-[(4-Bromo-2-fluorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-car
  • See more synonyms
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