CAS 6081-61-4

N-Benzyloxycarbonyl-D-serine

Description:

N-Benzyloxycarbonyl-D-serine, commonly referred to as Z-D-serine, is a derivative of the amino acid D-serine, characterized by the presence of a benzyloxycarbonyl (Z) protecting group on the amino group. This compound is typically used in peptide synthesis and as a building block in the preparation of various bioactive molecules. It is a white to off-white solid that is soluble in organic solvents such as methanol and dimethyl sulfoxide, but has limited solubility in water. The Z group serves to protect the amino functionality during chemical reactions, allowing for selective modifications of the carboxyl group or side chains. N-Benzyloxycarbonyl-D-serine is also of interest in biochemical research due to its role in studying the function of D-serine in neurotransmission and its potential implications in neuropharmacology. As with many chemical substances, proper handling and storage are essential, as it may pose hazards typical of organic compounds, including potential irritants or allergens.

Formula: C₁₁H₁₃NO₅

InChI: InChI=1/C11H13NO5/c13-6-9(10(14)15)12-11(16)17-7-8-4-2-1-3-5-8/h1-5,9,13H,6-7H2,(H,12,16)(H,14,15)/t9-/m1/s1

SMILES: c1ccc(cc1)COC(=N[C@H](CO)C(=O)O)O

Synonyms:

• (2R)-2-(Benzyloxycarbonyl)-3-hydroxypropanoic acid
• (2R)-3-Hydroxy-2-[(phenylmethoxy)carbonylamino]propionic acid
• (2R)-3-Hydroxy-2-[(phenylmethoxy)carbonylamino]propanoic acid
• (R)-2-(Benzyloxycarbonyl)-3-hydroxypropanoic acid
• (R)-3-Hydroxy-2-[(phenylmethoxy)carbonylamino]propionic acid
• D-Serine, N-[(phenylmethoxy)carbonyl]-
• D-serine, N-benzyloxycarbonyl-
• Z-D-Ser-OH
• N-Cbz-D-serine
• Cbz-D-serine
• N-(Benzyloxycarbonyl)-D-serine
• N-CARBOBENZOXY-D-SERINE
• BENZYLOXYCARBONYL-D-SERINE
• (R)-3-Hydroxy-2-(benzyloxycarbonylamino)propionic acid
• (2R)-2-(Benzyloxycarbonylamino)-3-hydroxypropionic acid
• (R)-2-[[(Benzyloxy)carbonyl]amino]-3-hydroxypropinic acid
• N-ALPHA-CBZ-D-SERINE
• Z-D-SERINE extrapure
• N-(Carbobenzyloxy)-D-serine
• CBZ-D-SER-OH
• N-ALPHA-CARBOBENZOXY-D-SERINE
• N-Benzyloxycarbonyl-D-serine,98+%

N-Benzyloxycarbonyl-D-serine

CAS: 6081-61-4

Formula: C₁₁H₁₃NO₅

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 239.23

Ref: 3B-C2137

N-Cbz-D-serine

CAS: 6081-61-4

Formula: C₁₁H₁₃NO₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 239.2246

Ref: IN-DA00E8TV

N-Cbz-D-Serine

CAS: 6081-61-4

N-Cbz-D-Serine

Purity: 98%

Molecular weight: 239.22g/mol

Ref: 54-OR471601

Cbz-D-Ser-OH

CAS: 6081-61-4

Formula: C₁₁H₁₃NO₅

Purity: 95%

Color and Shape: White to almost white powder

Molecular weight: 239.227

Ref: 10-F093729

N-Benzyloxycarbonyl-D-serine

Controlled Product

CAS: 6081-61-4

Applications N-Benzyloxycarbonyl-D-serine is D-serine (S270975) with amine protected from eletrophiles by carboxybenzyl group in organic synthesis. N-Benzyloxycarbonyl-D-serine can be used to synthesize acetamido-methoxypropionamides such as Desacetyl Desmethyl Lacosamide (D288325) which is a potent anticonvulsant.
References Letiran, A., et al.: J. Med. Chem., 45, 4762 (2002); Wadavrao, S., et al.: Synthesis, 45, 3383 (2013)

Formula: C₁₁H₁₃NO₅

Color and Shape: Neat

Molecular weight: 239.22

Ref: TR-B286730

Z-D-Serine extrapure, 99%

CAS: 6081-61-4

Formula: C₁₁H₁₃NO₅

Purity: min. 99 %

Color and Shape: White to off white, Crystalline  powder

Molecular weight: 239.2

Ref: SR-63273

Z-D-Ser-OH

CAS: 6081-61-4

Z-D-Ser-OH is a synthetic amino acid. It is a derivative of the natural amino acid serine which has an additional D-aminoacid in the chain. Z-D-Ser-OH can be used as a supplement for various purposes, such as to help maintain muscle mass and to support healthy immune function. This compound has been shown to have antibacterial properties. The synthesis of this compound starts with the condensation of L-serine and DL-alanine, followed by hydrolysis of the resulting imidazolide, acetylation, and formation of the cyclic peptide.

Formula: C₁₁H₁₃NO₅

Purity: Min. 95%

Molecular weight: 239.22 g/mol

Ref: 3D-FS37764