CAS 60940-34-3
:Ebselen
Description:
Ebselen, with the CAS number 60940-34-3, is an organoselenium compound known for its antioxidant and anti-inflammatory properties. It is a small molecule that mimics the activity of glutathione peroxidase, an important enzyme in cellular defense against oxidative stress. Ebselen exhibits a unique ability to scavenge free radicals and reduce lipid peroxidation, making it a potential therapeutic agent in various conditions associated with oxidative damage. Its structure features a selenoether moiety, which is crucial for its biological activity. Additionally, ebselen has been investigated for its neuroprotective effects and potential applications in treating conditions such as stroke and neurodegenerative diseases. The compound is also being explored for its antiviral properties, particularly against certain viral infections. Due to its diverse biological activities, ebselen is of significant interest in medicinal chemistry and pharmacology, although further research is needed to fully understand its mechanisms of action and therapeutic potential.
Formula:C13H9NOSe
InChI:InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H
InChI key:InChIKey=DYEFUKCXAQOFHX-UHFFFAOYSA-N
SMILES:O=C1N([Se]C=2C1=CC=CC2)C3=CC=CC=C3
Synonyms:- 1,2-Benzisoselenazol-3(2H)-one, 2-phenyl-
- 2-Phenyl-1,2-benzisoselenazol-3(2H)-one
- 2-Phenyl-1,2-benzoisoselenazol-3(2H)-one
- 2-Phenyl-1,2-benzoselenazol-3-one
- 2-Phenylbenzo[d][1,2]selenazol-3(2H)-one
- 2-phenyl-1,2-benzoselenazol-3(2H)-one
- Ccg-39161
- Dr 3305
- Lopac E 3520
- NSC 639762
- Pz 51
- Spi 1005
- See more synonyms
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Found 10 products.
Ebselen
CAS:Formula:C13H9NOSePurity:>98.0%(GC)Color and Shape:Light orange to Yellow to Green powder to crystalMolecular weight:274.18Ebselen
CAS:<p>Ebselen inhibits 5-LO, CO, NADPH oxidize, and protein kinase C. It is a potent antioxidant. It possesses a unique glutathione peroxidase-like activity. It is also shown to be an inhibitor of free radical induced apoptosis and neuroprotective agent. This Thermo Scientific Chemicals brand product was </p>Formula:C13H9NOSeColor and Shape:Crystals or powder or crystalline powder, White to yellow to greenMolecular weight:274.19Ebselen
CAS:<p>Ebselen is a selenium compound with anti-inflammatory and antioxidant properties, mimicking glutathione peroxidase to protect against ROS damage.</p>Formula:C13H9NOSePurity:98.99% - 99.94%Color and Shape:White SolidMolecular weight:274.18Ebselen
CAS:Formula:C13H9NOSePurity:≥ 98.0%Color and Shape:White to light-yellow or light-green powderMolecular weight:274.20Ebselen
CAS:<p>M01704 - Ebselen</p>Formula:C13H9NOSePurity:97%Color and Shape:slightly yellow solidMolecular weight:274.192Ebselen
CAS:<p>Ebselen is a non-toxic organoselenium compound with antioxidant, anti-inflammatory and cytoprotective properties. Ebselen is an inhibitor of lipoxygenases, nitric oxide (NO) synthases, protein kinase C, H+/K+-ATPase, thioredoxin reductase and NADPH oxidase. Recently, ebselen has been identified by several studies as a covalent inhibitor of the main protease Mpro from coronaviruses. For the SARS-CoV-2 main protease Mpro, the IC50 value is 0.67 μM and EC50 is 4.57 μM.</p>Formula:C13H9NOSePurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:274.18 g/mol2-Phenyl-1,2-benzoselenazol-3-one (Ebselen)
CAS:Controlled Product<p>Applications 2-Phenyl-1,2-benzoselenazol-3-one acts as an antiinfammatory compounds,, in addition to that it acts as a modulator of KVβ subunits.<br>References Wendel, A. et al.: Biochem. Pharmacol., 33, 3241 (1984);<br></p>Formula:C13H9NOSeColor and Shape:NeatMolecular weight:274.18
