CAS 61-76-7

(-)-Phenylephrine hydrochloride

Description:

(-)-Phenylephrine hydrochloride is a synthetic sympathomimetic amine primarily used as a decongestant and vasopressor. It is characterized by its ability to selectively stimulate alpha-1 adrenergic receptors, leading to vasoconstriction and increased blood pressure. This compound is typically presented as a white to off-white crystalline powder, soluble in water and alcohol, which facilitates its use in various pharmaceutical formulations. The molecular formula of (-)-Phenylephrine hydrochloride is C9H13NO2·HCl, and it has a molecular weight that reflects its structural components, including a phenolic group and an ethylamine side chain. Its stereochemistry is significant, as the (-) enantiomer is the active form responsible for its therapeutic effects. Commonly found in over-the-counter medications, it is utilized to relieve nasal congestion and as a mydriatic agent in ophthalmology. However, it is essential to monitor its use due to potential side effects, including hypertension and reflex bradycardia, particularly in sensitive populations.

Formula: C₉H₁₃NO₂·ClH

InChI: InChI=1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,9-12H,6H2,1H3;1H/t9-;/m0./s1

InChI key: InChIKey=OCYSGIYOVXAGKQ-FVGYRXGTSA-N

SMILES: [C@@H](CNC)(O)C1=CC(O)=CC=C1.Cl

Synonyms:

• (-)-α-Hydroxy-β-(methylamino)ethyl-α-(3-hydroxybenzene)hydrochloride
• (R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride
• (R)-3-(1-Hydroxy-2-(methylamino)ethyl)phenol hydrochloride
• (R)-3-Hydroxy-[α-(methylamino)methyl]benzene methanol hydrochloride
• (R)-3-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol hydrochloride
• (R)-Phenylephrine hydrochloride
• 3-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol hydrochloride
• Adrianol
• Ak-Dilate
• Ak-Nefrin
• Alcon Efrin
• Almefrin
• Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, hydrochloride (1:1), (αR)-
• Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, hydrochloride, (R)-
• Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, hydrochloride, (αR)-
• Benzyl alcohol, m-hydroxy-α-[(methylamino)methyl]-, hydrochloride, (-)-
• D-(-)-Phenylephrinehydrochloride
• Decadron
• Fenilefrina, Clorhidrato
• Irifrin
• Isophrin
• Isophrin hydrochloride
• Levophenylephrine hydrochloride
• Lexatol
• M-Sympatol
• Meta-Sympatol
• Meta-Synephrine hydrochloride
• Metaoxedrine chloride
• Metaoxedrine hydrochloride
• Mydfrin
• Neo-Synephrine hydrochloride
• Neo-Synesin 1
• Neophryn
• Neosinesine
• Nostril
• Oftalfrine
• Phenylephrine HCL
• Phenylephrine Hydrochloride
• Phenylephrine, chlorhydrate
• Phenylephrinhydrochlorid
• Prefrin
• Pyracort D
• R-(-)-m-Synephrine hydrochloride
• Sucraphen
• Synasal
• l-1-(m-Hydroxyphenyl)-2-methylaminoethanol hydrochloride
• l-m-Hydroxy-α-[(methylamino)methyl]benzyl alcohol hydrochloride
• l-α-Hydroxy-β-methylamino-3-hydroxy-1-ethylbenzene hydrochloride

(R)-Phenylephrine Hydrochloride

CAS: 61-76-7

Formula: C₉H₁₃NO₂·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystaline

Molecular weight: 203.67

Ref: 3B-P0398

Phenylephrine Hydrochloride

CAS: 61-76-7

Color and Shape: Neat

Ref: 61-FOR0081.00

Phenylephrine hydrochloride

CAS: 61-76-7

Phenylephrine hydrochloride

Formula: C₉H₁₃NO₂HCl

Purity: 100.0%

Color and Shape: White

Molecular weight: 203.07131

Ref: 47-284

PHENYLEPHRINE HYDROCHLORIDE CRS

CAS: 61-76-7

PHENYLEPHRINE HYDROCHLORIDE CRS

Ref: 41-P1250000

PHENYLEPHRINE HYDROCHLORIDE FOR PEAK IDENTIFICATION CRS

CAS: 61-76-7

PHENYLEPHRINE HYDROCHLORIDE FOR PEAK IDENTIFICATION CRS

Formula: C₉H₁₄ClNO₂

Molecular weight: 203.666

Ref: 41-Y0000683

Phenylephrine Hydrochloride

CAS: 61-76-7

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Formula: C₉H₁₃NO₂·ClH

Color and Shape: White Off-White Crystalline Powder

Molecular weight: 203.07131

Ref: 45-1533002

Phenylephrine hydrochloride

CAS: 61-76-7

Phenylephrine hydrochloride (NCI-c55641) is a selective agonist of the α1-adrenergic receptor.

Formula: C₉H₁₄ClNO₂

Purity: 99.51% - 99.97%

Color and Shape: Physical Description Odorless White Microcrystalline Powder Bitter Taste Ph (1%

Molecular weight: 203.67

Ref: TM-T0453

(R)-3-(1-Hydroxy-2-(methylamino)ethyl)phenol hydrochloride

CAS: 61-76-7

Formula: C₉H₁₄ClNO₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 203.6660

Ref: IN-DA00IAS9

Phenylephrine HCl

CAS: 61-76-7

Formula: C₉H₁₃NO₂·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 167.21 36.46

Ref: 4Z-P-2624

(R)-(-)-Phenylephrine hydrochloride, USP grade

CAS: 61-76-7

Formula: C₉H₁₃NO₂·HCl

Purity: 97.5 - 102.0 %

Color and Shape: White to off-white powder

Molecular weight: 203.67

Ref: 7W-GL0912

(R)-(-)-Phenylephrine hydrochloride

CAS: 61-76-7

Formula: C₉H₁₃NO₂·HCl

Purity: (Titration) ≥ 99.0% (dried basis)

Color and Shape: White to off-white powder

Molecular weight: 203.67

Ref: 7W-GL9617

Phenylephrine Hydrochloride

CAS: 61-76-7

Color and Shape: Neat

Ref: 86-MM0081.00

Phenylephrine Hydrochloride

CAS: 61-76-7

Formula: C₉H₁₃NO₂HCl

Molecular weight: 167.21 : 36.46

Ref: ST-EA-CP-P12016

(R)-Phenylephrine Hydrochloride

CAS: 61-76-7

Stability Hygroscopic
Applications (R)-Phenylephrine Hydrochloride is an α-Adrenergic agonist. Mydriatic; decongestant.
References Warren, M.R., et al.: J. Pharmacol. Exp. Ther., 86, 284 (1946); Gaglia, C.A., et al.: Anal. Profiles Drug Subs., 3, 483 (1974);

Formula: C₉H₁₃NO₂·ClH

Color and Shape: White To Off-White

Molecular weight: 203.67

Ref: TR-P320640

Phenylephrine hydrochloride

CAS: 61-76-7

(R)-Phenylephrine hydrochloride is a non selective alpha adrenergic agonist that can be used as a bronchodilator or vasopressor. Some research studies in rat liver microsomes has shown that (R)-phenylephrine can be converted to phenylephrine by alcohol dehydrogenase at a rate constant of around 1.8x103 M-1s-1 at 37°C. The biological effects of this compound are due to its ability to cause relaxation of smooth muscle and increase blood pressure by stimulating alpha-adrenergic receptors in the body. This drug is also used in chromatography for control analysis and detection of adulteration with other compounds, such as norepinephrine, with the help of benzalkonium chloride.In ophthalmology, phenylephrine hydrochloride formulations are used for the treatment of eye disorders such as myopia, hypermetropia and astigmatism. It increases the outflow of aqueous humour from the eye by acting on alpha receptors in the ciliary body, and seems to be effective in controlling symptoms of allergic rhinitis and chronic urticaria.

Formula: C₉H₁₄NO₂Cl

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 203.67 g/mol

Ref: 3D-FP26956

(R)-Phenylephrine HCl - Bio-X ™

CAS: 61-76-7

(R)-Phenylephrine is a non-selective α1-adrenoceptor agonist that can be used as a bronchodilator or vasopressor. The biological effects of this compound are due to its ability to cause relaxation of smooth muscle cells and increase blood pressure by stimulating alpha-adrenergic receptors in the body. Also, this drug is used to relieve nasal discomfort caused by colds and allergies and is used to relieve sinus congestion and pressure.

Formula: C₉H₁₃NO₂•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 203.67 g/mol

Ref: 3D-BP166231