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CAS 61-76-7

:

(-)-Phenylephrine hydrochloride

Description:
(-)-Phenylephrine hydrochloride is a synthetic sympathomimetic amine primarily used as a decongestant and vasopressor. It is characterized by its ability to selectively stimulate alpha-1 adrenergic receptors, leading to vasoconstriction and increased blood pressure. This compound is typically presented as a white to off-white crystalline powder, soluble in water and alcohol, which facilitates its use in various pharmaceutical formulations. The molecular formula of (-)-Phenylephrine hydrochloride is C9H13NO2·HCl, and it has a molecular weight that reflects its structural components, including a phenolic group and an ethylamine side chain. Its stereochemistry is significant, as the (-) enantiomer is the active form responsible for its therapeutic effects. Commonly found in over-the-counter medications, it is utilized to relieve nasal congestion and as a mydriatic agent in ophthalmology. However, it is essential to monitor its use due to potential side effects, including hypertension and reflex bradycardia, particularly in sensitive populations.
Formula:C9H13NO2·ClH
InChI:InChI=1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,9-12H,6H2,1H3;1H/t9-;/m0./s1
InChI key:InChIKey=OCYSGIYOVXAGKQ-FVGYRXGTSA-N
SMILES:[C@@H](CNC)(O)C1=CC(O)=CC=C1.Cl
Synonyms:
  • (-)-α-Hydroxy-β-(methylamino)ethyl-α-(3-hydroxybenzene)hydrochloride
  • (R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride
  • (R)-3-(1-Hydroxy-2-(methylamino)ethyl)phenol hydrochloride
  • (R)-3-Hydroxy-[α-(methylamino)methyl]benzene methanol hydrochloride
  • (R)-3-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol hydrochloride
  • (R)-Phenylephrine hydrochloride
  • 3-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol hydrochloride
  • Adrianol
  • Ak-Dilate
  • Ak-Nefrin
  • See more synonyms
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