CAS 6112-76-1: 6-Mercaptopurine monohydrate

Description: 6-Mercaptopurine monohydrate is a purine analog and an antimetabolite used primarily in the treatment of certain types of leukemia and autoimmune diseases. It is characterized by its chemical formula C5H6N4S·H2O, indicating the presence of a mercapto group (-SH) that contributes to its reactivity and biological activity. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in clinical settings. Its mechanism of action involves the inhibition of purine nucleotide synthesis, thereby interfering with DNA and RNA synthesis, which is crucial for rapidly dividing cells. 6-Mercaptopurine is often administered in conjunction with other medications to enhance therapeutic efficacy and reduce the risk of resistance. Due to its potential for toxicity, careful monitoring of blood counts and liver function is essential during treatment. Additionally, it is important to consider genetic factors, such as variations in the TPMT enzyme, which can affect individual responses to the drug.

Formula: C₅H₄N₄S·H₂O

InChI: InChI=1S/C5H4N4S.H2O/c10-5-3-4(7-1-6-3)8-2-9-5;/h1-2H,(H2,6,7,8,9,10);1H2

InChI key: InChIKey=WFFQYWAAEWLHJC-UHFFFAOYSA-N

SMILES: S=C1N=CNC=2N=CNC12.O

Synonyms:

• 1,4,5,7-Tetrahydro-6H-Purine-6-Thione Hydrate
• 1,7-Dihydro-6H-Purin-6-Thion,Monohydrat
• 1,7-Dihydro-6H-Purine-6-Thionemonohydrate
• 1,7-Dihydro-6H-Purine-6-Thionmonohydrate
• 3,7-Dihydro-6H-Purine-6-Thione Hydrate
• 6-Mercapto Purine
• 6-Mercaptopurine Hydrate
• 6-Merkaptopurin,Monohydrat
• 6-Purinethiol Monohydrate
• 6-Thiohypoxanthine Monohydrate
• 6H-Purin-6-Thion,Monohydrat
• 6H-Purine-6-thione, 1,2,3,9-tetrahydro-, hydrate (1:1)
• 6H-Purine-6-thione, 1,7-dihydro-, monohydrate
• 7H-Purine-6-Thiolate
• 9H-Purine-6-thiol hydrate
• Leukerin Monohydrate
• Mercaleukin Monohydrate
• Mercaptopurine Monohydrate, 6-Mercaptopurine
• Mercaptopurine, Monohydrate
• Purin-6-Thiol,Monohydrat
• Purine-6-Thiol, Monohydrate
• Xaluprine
• 6-Mercaptopurine monohydrate
• 6H-Purine-6-thione, 1,9-dihydro-, hydrate (1:1)

6-Mercaptopurine monohydrate, 98%

CAS: 6112-76-1

6-Mercaptopurine is a widely used antileukemic agent that inhibits de novopurine synthesis through incorporation of …

• Formula: C₅H₆N₄OS
• Purity: 98%
• Color and Shape: Yellow, Powder
• Molecular weight: 170.19

Mercaptopurine impurity standard

CAS: 154-42-7 6112-76-168-94-0 73-24-5

• Color and Shape: Yellow

Mercaptopurine

CAS: 6112-76-1

• Formula: C₅H₄N₄SH₂O
• Purity: 98.8%
• Color and Shape: Yellow
• Molecular weight: 170.02623

Mercaptopurine monohydrate CRS

CAS: 6112-76-1

Mercaptopurine

CAS: 6112-76-1

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

• Formula: C₅H₄N₄S·H₂O
• Color and Shape: Yellow Crystalline Powder
• Molecular weight: 152.01567

6-Mercaptopurine monohydrate

CAS: 6112-76-1

• Formula: C₅H₆N₄OS
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 170.1923

6-Mercaptopurine hydrate

CAS: 6112-76-1

• Purity: ≥98%
• Molecular weight: 170.19g/mol

6-Mercaptopurine monohydrate

CAS: 6112-76-1

• Formula: C₅H₄N₄SH₂O
• Molecular weight: 170.19

6-Mercaptopurine-13C-15N2 (Azathioprine EP Impurity B-13C-15N2)

CAS: 207729-57-5 50-44-2 6112-76-1

• Formula: C₄₁₃CH₄N₂₁₅N₂S
• Molecular weight: 155.15

6-Mercaptopurine Monohydrate

CAS: 50-44-2 6112-76-1

• Formula: C₅H₄N₄S·H₂O
• Purity: >98.0%(T)(HPLC)
• Color and Shape: Light yellow to Yellow powder to crystal
• Molecular weight: 170.20

6-Mercaptopurine monohydrate, 98%

CAS: 6112-76-1

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₅H₆N₄OS
• Purity: 98%
• Molecular weight: 170.19

Mercaptopurine Monohydrate

CAS: 6112-76-1

• Formula: C₅H₄N₄S·H₂O
• Color and Shape: Neat
• Molecular weight: 170.19

6-Mercaptopurine monohydrate

CAS: 6112-76-1

• Formula: C5H4N4S.H2O
• Color and Shape: Light yellow powder
• Molecular weight: 170.1923

6-Mercaptopurine monohydrate

CAS: 6112-76-1

• Formula: C₅H₄N₄S·H₂O
• Purity: By hplc: 98.7% (Typical Value in Batch COA)
• Color and Shape: yellow powder
• Molecular weight: 170.19g/mol

6-Mercaptopurine Monohydrate (Azathioprine EP Impurity B Monohydrate)

CAS: 6112-76-1

• Formula: C₅H₄N₄S·H₂O
• Molecular weight: 152.18 18.02

6-Mercaptopurine hydrate

CAS: 6112-76-1

6-Mercaptopurine hydrate is a leukemia treatment; it blocks purine metabolism, affecting DNA synthesis.

• Formula: C₅H₆N₄OS
• Purity: 97.54% - 99.14%
• Color and Shape: Light Yellow Crystalline Powder
• Molecular weight: 170.19

6-Mercaptopurine Monohydrate

CAS: 6112-76-1

Applications An immunosuppressive drug used to treat leukemia. It is also used for pediatric non-Hodgkin’s …

• Formula: C₅H₄N₄S·H₂O
• Color and Shape: Yellow
• Molecular weight: 170.19

6-Mercaptopurine monohydrate

CAS: 6112-76-1

• Purity: 98.0%
• Color and Shape: Solid
• Molecular weight: 170.19

6-Mercaptopurine hydrate

CAS: 6112-76-1

Please enquire for more information about 6-Mercaptopurine hydrate including the price, delivery time and more …

• Formula: C₅H₄N₄S•H₂O
• Purity: Min. 97 Area-%
• Color and Shape: Yellow Powder
• Molecular weight: 152.18 g/mol

6-Mercaptopurine Monohydrate extrapure, 99%

CAS: 6112-76-1

• Formula: C₅H₄N₄S·H₂O
• Purity: min. 99%
• Color and Shape: Yellow, Crystalline powder
• Molecular weight: 170.19