CAS 6160-80-1

4-Methylumbelliferyl β-D-glucuronide

Description:

4-Methylumbelliferyl β-D-glucuronide (MUG) is a synthetic compound commonly used as a substrate in biochemical assays, particularly for the detection of β-glucuronidase activity. It is a colorless, crystalline solid that is soluble in water and organic solvents. The compound is characterized by its fluorescent properties; upon hydrolysis by β-glucuronidase, it releases 4-methylumbelliferone, which emits a strong blue fluorescence when excited by ultraviolet light. This property makes MUG a valuable tool in various applications, including microbiology for detecting E. coli and other bacteria that produce β-glucuronidase. MUG is stable under normal laboratory conditions but should be stored in a cool, dry place away from light to maintain its integrity. Safety precautions should be taken when handling this compound, as with any chemical, to avoid potential hazards. Overall, 4-Methylumbelliferyl β-D-glucuronide is an important reagent in enzymatic assays and research involving glucuronidation processes.

Formula: C₁₆H₁₆O₉

InChI: InChI=1S/C16H16O9/c1-6-4-10(17)24-9-5-7(2-3-8(6)9)23-16-13(20)11(18)12(19)14(25-16)15(21)22/h2-5,11-14,16,18-20H,1H3,(H,21,22)/t11-,12-,13+,14-,16+/m0/s1

InChI key: InChIKey=ARQXEQLMMNGFDU-JHZZJYKESA-N

SMILES: CC=1C=2C(=CC(O[C@@H]3O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]3O)=CC2)OC(=O)C1

Synonyms:

• (2S,3R,4S,5R,6S)-3,4,5-trihydroxy-6-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]tetrahydro-2H-pyran-2-carboxylate (non-preferred name)
• (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]tetrahydro-2H-pyran-2-carboxylate (non-preferred name)
• 2H-1-Benzopyran-2-one, 7-(beta-D-glucopyranuronosyloxy)-4-methyl-
• 4-Methyl-2-oxo-2H-1-benzopyran-7-yl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
• 4-Methyl-2-oxo-2H-chromen-7-yl beta-D-glucopyranosiduronic acid
• 4-Methylumbelliferone glucuronide
• 4-Methylumbelliferone β-<span class="text-smallcaps">D</span>-glucuronide
• 4-Methylumbelliferyl glucuronide
• 4-Methylumbelliferyl-Beta-D-Glucuronide
• 4-Methylumbelliferyl-β-<span class="text-smallcaps">D</span>-glucuronic acid
• 4-Mug
• Glucopyranosiduronic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl, β-<span class="text-smallcaps">D</span>-
• Hymecromon-7-O-4-β-<span class="text-smallcaps">D</span>-glucuronide
• β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl
• β-D-Glucopyranosiduronic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl
• 4-Methylumbelliferyl β-D-glucuronide
• Glucopyranosiduronic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl, β-D-

4-Methylumbelliferyl-β-D-glucuronide, 98%

CAS: 6160-80-1

It is a fluorogenic substrate for measuring of -glucoronidiase activity, for rapid sensitive identification of Escherichia coli. MUG is a substrate for glucuronidase. It is ideal for plant molecular study as a way to examine gene expression under various promoters. And while it works well for measur

Formula: C₁₆H₁₆O₉

Purity: 98%

Color and Shape: White, Crystals or powder or crystalline powder

Molecular weight: 352.30

Ref: 02-B21190

4-Methylumbelliferyl--D-glucuronide

CAS: 6160-80-1

Formula: C₁₆H₁₆O₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 352.2928

Ref: IN-DA003LT2

4-Methylumbelliferyl b-D-glucuronide hydrate

CAS: 6160-80-1

Formula: C₁₆H₁₆O₉·xH₂O

Purity: ≥ 99%

Color and Shape: White crystalline powder

Molecular weight: 352.29 (anhydrous)

Ref: 7W-GC5027

4-Methylumbelliferyl-β-D-glucuronide trihydrate

CAS: 6160-80-1

4-Methylumbelliferyl-β-D-glucuronide trihydrate

Formula: C₁₆H₁₆O₉·3H₂O

Purity: >98%

Color and Shape: white crystalline powder

Molecular weight: 406.34g/mol

Ref: 54-BIMB1003

Hymecromone-β-D-Glucuronide

CAS: 6160-80-1

Formula: C₁₆H₁₆O₉

Molecular weight: 352.30

Ref: 4Z-H-092004

4-Methylumbelliferyl b-D-Glucuronide

Controlled Product

CAS: 6160-80-1

Stability Hygroscopic
Applications 4-Methylumbelliferyl β-D-Glucuronide is a substrate for glucuronidase. Also used as a test for coliform bacteria in water.Fluorescence: max. Abs. 316nm; max. Em. 375nm; e x 10-3: 12
References US Federal Register, 57, 24744 (1992)

Formula: C₁₆H₁₆O₉

Color and Shape: Neat

Molecular weight: 352.29

Ref: TR-M334550

4-Methylumbelliferyl β-D-glucuronide Dihydrate

Controlled Product

CAS: 6160-80-1, 881005-91-0

Applications 4-Methylumbelliferyl β-D-glucuronide dihydrate is a useful building block and a fluorophore.
References Santocki, M.; et al.: Folia Biologia, 64, 122 (2016).

Formula: C₁₆H₁₆O₉·2H₂O

Color and Shape: Neat

Molecular weight: 352.29

Ref: TR-M849655

4-Methylumbelliferyl β-D-glucuronide

CAS: 6160-80-1

Fluorogenic substrate for b-glucuronidase GUS

Formula: C₁₆H₁₆O₉

Purity: Min. 95%

Molecular weight: 352.29 g/mol

Ref: 3D-EM58443

Hymecromone-β-D-Glucuronide

CAS: 6160-80-1

Formula: C₁₆H₁₆O₉

Molecular weight: 352.30

Ref: ST-EA-CP-H32003