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CAS 6160-80-1

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4-Methylumbelliferyl β-D-glucuronide

Description:
4-Methylumbelliferyl β-D-glucuronide (MUG) is a synthetic compound commonly used as a substrate in biochemical assays, particularly for the detection of β-glucuronidase activity. It is a colorless, crystalline solid that is soluble in water and organic solvents. The compound is characterized by its fluorescent properties; upon hydrolysis by β-glucuronidase, it releases 4-methylumbelliferone, which emits a strong blue fluorescence when excited by ultraviolet light. This property makes MUG a valuable tool in various applications, including microbiology for detecting E. coli and other bacteria that produce β-glucuronidase. MUG is stable under normal laboratory conditions but should be stored in a cool, dry place away from light to maintain its integrity. Safety precautions should be taken when handling this compound, as with any chemical, to avoid potential hazards. Overall, 4-Methylumbelliferyl β-D-glucuronide is an important reagent in enzymatic assays and research involving glucuronidation processes.
Formula:C16H16O9
InChI:InChI=1S/C16H16O9/c1-6-4-10(17)24-9-5-7(2-3-8(6)9)23-16-13(20)11(18)12(19)14(25-16)15(21)22/h2-5,11-14,16,18-20H,1H3,(H,21,22)/t11-,12-,13+,14-,16+/m0/s1
InChI key:InChIKey=ARQXEQLMMNGFDU-JHZZJYKESA-N
SMILES:CC=1C=2C(=CC(O[C@@H]3O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]3O)=CC2)OC(=O)C1
Synonyms:
  • (2S,3R,4S,5R,6S)-3,4,5-trihydroxy-6-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]tetrahydro-2H-pyran-2-carboxylate (non-preferred name)
  • (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]tetrahydro-2H-pyran-2-carboxylate (non-preferred name)
  • 2H-1-Benzopyran-2-one, 7-(beta-D-glucopyranuronosyloxy)-4-methyl-
  • 4-Methyl-2-oxo-2H-1-benzopyran-7-yl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
  • 4-Methyl-2-oxo-2H-chromen-7-yl beta-D-glucopyranosiduronic acid
  • 4-Methylumbelliferone glucuronide
  • 4-Methylumbelliferone β-<span class="text-smallcaps">D</span>-glucuronide
  • 4-Methylumbelliferyl glucuronide
  • 4-Methylumbelliferyl-Beta-D-Glucuronide
  • 4-Methylumbelliferyl-β-<span class="text-smallcaps">D</span>-glucuronic acid
  • See more synonyms
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