CAS 62-13-5

Ethanone, 1-(3,4-dihydroxyphenyl)-2-(methylamino)-, hydrochloride (1:1)

Description:

Ethanone, 1-(3,4-dihydroxyphenyl)-2-(methylamino)-, hydrochloride (1:1), commonly known as methyldopa, is a pharmaceutical compound primarily used as an antihypertensive agent. It is characterized by its ability to lower blood pressure by acting as a centrally acting alpha-2 adrenergic agonist. The chemical structure features a dihydroxyphenyl group, which contributes to its biological activity, and a methylamino group that enhances its solubility and pharmacological properties. Methyldopa is typically administered in its hydrochloride salt form, which improves its stability and bioavailability. The compound is known for its relatively mild side effect profile compared to other antihypertensives, making it suitable for use in pregnant women. Its mechanism of action involves the conversion to alpha-methyl norepinephrine, which stimulates central alpha-adrenergic receptors, leading to reduced sympathetic outflow and decreased peripheral vascular resistance. Methyldopa is generally well-tolerated, but it can cause side effects such as sedation, dry mouth, and, in rare cases, liver dysfunction.

Formula: C₉H₁₁NO₃·ClH

InChI: InChI=1S/C9H11NO3.ClH/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;/h2-4,10-12H,5H2,1H3;1H

InChI key: InChIKey=CSRRBDMYOUQTCO-UHFFFAOYSA-N

SMILES: C(CNC)(=O)C1=CC(O)=C(O)C=C1.Cl

Synonyms:

• 1-(3,4-Dihydroxyphenyl)-2-(Methylamino)Ethanone
• 1-(3,4-Dihydroxyphenyl)-2-(Methylamino)Ethanone Hydrochloride (1:1)
• 1-(3,4-Dihydroxyphenyl)-2-(methylamino)ethan-1-one hydrochloride
• Acetophenone, 3′,4′-dihydroxy-2-(methylamino)-, hydrochloride
• Adrenalone hydrochloride
• Adrenone hydrochloride
• Ethanone, 1-(3,4-dihydroxyphenyl)-2-(methylamino)-, hydrochloride
• Ethanone, 1-(3,4-dihydroxyphenyl)-2-(methylamino)-, hydrochloride (1:1)
• Kephrine hydrochloride
• Styphnonasal
• [2-(3,4-Dihydroxyphenyl)-2-oxoethyl](methyl)azanium chloride

Adrenalone Hydrochloride

CAS: 62-13-5

Unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives, nesoi

Formula: C₉H₁₁NO₃·HCl

Color and Shape: White Beige Powder

Molecular weight: 217.05057

Ref: 45-1011878

Adrenalone hydrochloride

CAS: 62-13-5

Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.

Formula: C₉H₁₁NO₃·HCl

Purity: 99.94%

Color and Shape: Solid

Molecular weight: 217.65

Ref: TM-T0948

Adrenalone HCl (Adrenaline EP Impurity C HCl)

CAS: 62-13-5

Formula: C₉H₁₁NO₃·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 181.19 36.46

Ref: 4Z-A-981

1-(3,4-Dihydroxyphenyl)-2-(methylamino)ethanone Hydrochloride (Adrenalone Hydrochloride)

Controlled Product

CAS: 62-13-5

Formula: C₉H₁₁NO₃·ClH

Color and Shape: Neat

Molecular weight: 217.65

Ref: 86-MM0614.13

Adrenalone Hydrochloride

CAS: 62-13-5

Formula: C₉H₁₁NO₃·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 217.65

Ref: 3B-A1234

Adrenalone Hydrochloride Hydrate

CAS: 62-13-5

Applications Adrenalone displays antineoplastic activity and has been shown to inhibit growth of Ehrlich ascites tumors in mice.
References Malyugina, L.L. et al.: Khim.-Fam. Zh., 13, 56 (1979); Watson, J.R. et al.: J. Pharm. Sci., 66, 560 (1977);

Formula: C₉H₁₁NO₃·ClH

Color and Shape: Off-White

Molecular weight: 217.65

Ref: TR-A305100

1-(3,4-dihydroxyphenyl)-2-(methylamino)ethanone hydrochloride

CAS: 62-13-5

Formula: C₉H₁₂ClNO₃

Purity: 98%;RG

Color and Shape: Solid

Molecular weight: 217.65

Ref: 10-F391965

Adrenaline EP Impurity C

CAS: 62-13-5

Formula: C₉H₁₁NO₃HCl

Molecular weight: 181.2 : 36.46

Ref: ST-EA-CP-A91003

Adrenalone Hydrochloride

CAS: 62-13-5

Formula: C₉H₁₁NO₃HCl

Molecular weight: 181.2 : 36.46

Ref: ST-EA-CP-A49002

Adrenalone hydrochloride

Controlled Product

CAS: 62-13-5

Adrenalone hydrochloride is a synthetic form of epinephrine, which is an endogenous catecholamine. Adrenalone hydrochloride has been used to treat autoimmune diseases and bowel disease. Adrenalone hydrochloride binds to the alpha and beta receptors on the surface of cells, which stimulates the production of other hormones and neurotransmitters. It has also been shown to have antimicrobial properties against bacteria, fungi, and viruses. Adrenalone hydrochloride has a chemical stability that is greater than that of dopamine or adrenaline.

Formula: C₉H₁₁NO₃·HCl

Purity: Min. 95%

Molecular weight: 217.65 g/mol

Ref: 3D-FA50921