CAS 62-50-0

Ethyl methanesulfonate

Description:

Ethyl methanesulfonate (EMS) is an organic compound with the chemical formula C3H8O3S and a CAS number of 62-50-0. It is a colorless to pale yellow liquid that is highly soluble in water and polar organic solvents. EMS is primarily known as a potent alkylating agent, which means it can introduce alkyl groups into other molecules, making it valuable in various chemical reactions, particularly in the synthesis of pharmaceuticals and agrochemicals. Due to its reactivity, EMS is also used in molecular biology for mutagenesis, where it induces mutations in DNA. However, it is important to handle EMS with caution, as it is classified as a hazardous substance and can pose health risks, including potential carcinogenic effects. Proper safety measures, including the use of personal protective equipment and working in a fume hood, are essential when working with this compound. Overall, ethyl methanesulfonate is a versatile chemical with significant applications in both research and industry, but it requires careful handling due to its toxicological properties.

Formula: C₃H₈O₃S

InChI: InChI=1S/C3H8O3S/c1-3-6-7(2,4)5/h3H2,1-2H3

InChI key: InChIKey=PLUBXMRUUVWRLT-UHFFFAOYSA-N

SMILES: O(S(C)(=O)=O)CC

Synonyms:

• EMS
• Ethyl Methanesulphonate
• Ethyl mesylate
• Ethyl methane sulfonate
• Ethyl methanesulfonate
• Ethylmethansulfonat
• Metanosulfonato De Etilo
• Methanesulfonate d'ethyle
• Methansulfonsaeure-Aethylester
• Methylsulfonate, Ethyl
• Nsc 26805
• O-Ethyl methylsulfonate
• AI3-26396
• RCRA waste number U119
• Methylsulfonic acid, ethyl ester
• BRN 0773969
• CCRIS 299
• Ethyl ester of methanesulphonic acid
• Ethylester kyseliny methansulfonove [Czech]
• Ethyl methansulphonate
• Methanesulfonic acid, ethyl ester
• ENT 26396
• CB 1528
• HSDB 4007
• Ethyl ester of methanesulfonic acid
• Ethylester kyseliny methansulfonove
• Methanesulphonic acid ethyl ester
• Ethyl ester of methylsulphonic acid
• Ethyl ester of methylsulfonic acid
• Half-myleran
• RCRA waste no. U119

Ethyl Methanesulfonate

CAS: 62-50-0

Formula: C₃H₈O₃S

Purity: >99.0%(GC)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 124.15

Ref: 3B-M0607

Ethyl methanesulfonate, 99%

CAS: 62-50-0

Ethyl methanesulfonate is used as mutagen for both mammalian and plant cells. It finds application as a model alkylating agent in the study of deoxyribonucleic acid (DNA) repair processes. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some do

Formula: C₃H₈O₃S

Purity: 99%

Color and Shape: Clear colorless, Liquid

Molecular weight: 124.15

Ref: 02-A12938

Ethyl methanesulfonate

CAS: 62-50-0

Formula: C₃H₈O₃S

Purity: 98%

Color and Shape: Liquid

Molecular weight: 124.1588

Ref: IN-DA0034WH

Ethyl Methanesulfonate

CAS: 62-50-0

Formula: C₃H₈O₃S

Color and Shape: Colorless Liquid

Molecular weight: 124.15

Ref: 4Z-M-871

Ethyl methanesulfonate

CAS: 62-50-0

Formula: C₃H₈O₃S

Purity: ≥ 98.0%

Color and Shape: Clear, colourless to light yellow liquid

Molecular weight: 124.15

Ref: 7W-GX0446

Ethyl Methanesulfonate

CAS: 62-50-0

Ethyl Methanesulfonate

Formula: C₃H₈O₃S

Purity: 99%

Color and Shape: Liquid

Molecular weight: 124.16

Ref: 54-OR1013246

EPA Method 8270 Appendix IX Mixture 2 1000 µg/mL in Dichloromethane

Controlled Product

CAS: 100-52-7, 101-84-8, 105-60-2, 120-58-1, 123-91-1, 130-15-4, 140-57-8, 143-50-0, 1888-71-7, 224-42-0, 2303-16-4, 23950-58-5, 465-73-6, 510-15-6, 56-49-5, 56-57-5, 57-97-6, 608-93-5, 62-44-2, 62-50-0, 66-27-3, 76-01-7, 82-68-8, 87-65-0, 90-13-1, 92-52-4, 94-59-7, 95-94-3, 97-63-2, 98-86-2, 99-35-4

Formula: C₆H₂Cl₄

Color and Shape: Mixture

Molecular weight: 215.89

Ref: 04-GA09000445DI

Ethylmethanesulfonate

Controlled Product

CAS: 62-50-0

Formula: C₃H₈O₃S

Color and Shape: Neat

Molecular weight: 124.16

Ref: 04-C13346500

Ethyl Methanesulfonate

CAS: 62-50-0

Formula: C₃H₈O₃S

Molecular weight: 124.15

Ref: ST-EA-CP-I5035

Ethyl Methanesulfonate

Controlled Product

CAS: 62-50-0

Stability Moisture Sensitive
Applications Ethyl Methanesulfonate is used in studies as DNA damage specific control of cell death by cryptochrome in p53-mutant Ras-transformed cells.
References Lee, J.H., et al.: Cancer Res., 73, 785 (2013);

Formula: C₃H₈O₃S

Color and Shape: Neat

Molecular weight: 124.16

Ref: TR-E917995

Ethyl methanesulfonate

CAS: 62-50-0

Formula: C₃H₈O₃S

Purity: 98%

Color and Shape: Liquid

Molecular weight: 124.15

Ref: 10-F001758

Methanesulfonic acid ethyl ester

Controlled Product

CAS: 62-50-0

Methanesulfonic acid ethyl ester is a glycosidic bond-forming agent that is used in the production of certain polymers. It has an optimum concentration of 2.5 mM and can be used as an effector protein to study polymerase chain reaction (PCR). Methanesulfonic acid ethyl ester is genotoxic and is not carcinogenic, but can result in genotoxic effects at high concentrations. Methanesulfonic acid ethyl ester binds to DNA by reacting with the hydroxyl group on the second carbon of a fatty acid, which facilitates covalent binding to DNA. This agent also inhibits RNA synthesis, leading to cell death. Model organisms such as yeast have been used to investigate the effect of methanesulfonic acid ethyl ester on cell growth. The use of tissue culture for this type of experiment has also been studied extensively.

Formula: C₃H₈O₃S

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 124.16 g/mol

Ref: 3D-FM11879

Ethyl Mesylate

CAS: 62-50-0

Hydrocarbon derivatives containing only sulfo groups, their salts andesters

Formula: C₃H₈O₃S

Color and Shape: Clear Colorless Liquid

Molecular weight: 124.01942

Ref: 45-1394014

Ethyl Methanesulphonate (EMS) for tissue culture, 98%

CAS: 62-50-0

Formula: C₃H₈SO₃

Purity: min. 98%

Color and Shape: Clear, Colourless, Liquid

Molecular weight: 124.15

Ref: SR-27035

Ethyl Methanesulphonate (EMS) extrapure, 98%

CAS: 62-50-0

Formula: C₃H₈SO₃

Purity: min. 98%

Color and Shape: Clear, Colourless, Liquid

Molecular weight: 124.15

Ref: SR-85108