CAS 62004-35-7

(Z)-2-cyano-N-(2,5-dibromophenyl)-3-hydroxy-but-2-enamide

Description:

(Z)-2-cyano-N-(2,5-dibromophenyl)-3-hydroxy-but-2-enamide is a chemical compound characterized by its unique structural features, including a cyano group, a hydroxyl group, and an amide functional group. The presence of the dibromophenyl moiety contributes to its potential reactivity and biological activity, as halogenated compounds often exhibit distinct properties. The (Z) configuration indicates that the substituents around the double bond are on the same side, which can influence the compound's stereochemistry and interactions with biological targets. This compound may exhibit various properties such as solubility in organic solvents, potential for hydrogen bonding due to the hydroxyl group, and the ability to participate in nucleophilic reactions due to the cyano group. Its specific applications and biological activities would depend on further studies, but compounds with similar structures are often explored in medicinal chemistry for their potential therapeutic effects. As with any chemical substance, safety and handling precautions should be observed due to the presence of bromine, which can pose environmental and health risks.

Formula: C₁₁H₈Br₂N₂O₂

InChI: InChI=1/C11H8Br2N2O2/c1-6(16)8(5-14)11(17)15-10-4-7(12)2-3-9(10)13/h2-4,16H,1H3,(H,15,17)/b8-6-

InChI key: UVSVTDVJQAJIFG-SOFGYWHQSA-N

SMILES: C/C(=C(\C#N)/C(=Nc1cc(ccc1Br)Br)O)/O

Synonyms:

• (2Z)-2-cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enamide
• Lfm-A13

LFM-A13

CAS: 62004-35-7

Formula: C₁₁H₈Br₂N₂O₂

Purity: >98.0%(HPLC)

Color and Shape: Light yellow to Brown powder to crystal

Molecular weight: 360.01

Ref: 3B-L0309

2-Cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enamide

CAS: 62004-35-7

2-Cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enamide

Formula: C₁₁H₈Br₂N₂O₂

Purity: 99.5%

Molecular weight: 360.01

Ref: 54-OR1067136

LFM-A13

CAS: 62004-35-7

LFM-A13 is a highly selective BTK inhibitor; IC50 2.5 uM; targets catalytic domain; severs BCR signaling; anti-leukemic; autoimmune disease and lymphocytic leukemia research.

Formula: C₁₁H₈Br₂N₂O₂

Purity: 99.50%

Color and Shape: White Solid

Molecular weight: 360

Ref: TM-T212732

LFM-A13

CAS: 62004-35-7

Formula: C₁₁H₈Br₂N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 360.0014

Ref: IN-DA00EB3N

2-cyano-N-(2,5-dibromophenyl)-3-oxobutanamide

CAS: 62004-35-7

Purity: ≥98%(HPLC)

Molecular weight: 360.005

Ref: 10-F980528

LFM-A13

CAS: 62004-35-7

LFM-A13 is a small molecule that disrupts the mitochondrial membrane potential. It has been shown to have significant effects on myeloma cells in vitro and may have applications in autoimmune diseases and other inflammatory diseases. LFM-A13 also binds to the Toll-like receptor 4 (TLR4) and inhibits its activation, reducing inflammation by inhibiting the production of proinflammatory cytokines. LFM-A13 is a potent inhibitor of protein synthesis, which can be attributed to its ability to inhibit kinase activity. LFM-A13 is stable in vivo and has been shown to cross the blood brain barrier.

Formula: C₁₁H₈Br₂N₂O₂

Purity: Min. 95%

Molecular weight: 360 g/mol

Ref: 3D-MCA00435