CAS 62037-41-6

ala-ala-phe 7-amido-4-methylcoumarin

Description:

Ala-ala-phe 7-amido-4-methylcoumarin, also known by its CAS number 62037-41-6, is a synthetic compound that belongs to the class of coumarin derivatives. This substance is characterized by its structure, which includes a coumarin core modified with an amide group and a peptide sequence consisting of alanine and phenylalanine. The compound is often utilized in biochemical research, particularly in studies involving enzyme activity and peptide interactions, due to its fluorescent properties. The 7-amido group enhances its solubility and reactivity, making it suitable for various applications in biochemistry and molecular biology. Its fluorescence can be exploited in assays to monitor enzymatic reactions or to study protein interactions. Additionally, the presence of the aromatic phenylalanine residue contributes to its potential interactions with biological macromolecules. Overall, this compound serves as a valuable tool in the exploration of biochemical processes and the development of fluorescent probes.

Formula: C₂₅H₂₈N₄O₅

InChI: InChI=1/C25H28N4O5/c1-14-11-22(30)34-21-13-18(9-10-19(14)21)28-25(33)20(12-17-7-5-4-6-8-17)29-24(32)16(3)27-23(31)15(2)26/h4-11,13,15-16,20H,12,26H2,1-3H3,(H,27,31)(H,28,33)(H,29,32)

SMILES: Cc1cc(=O)oc2cc(ccc12)N=C(C(Cc1ccccc1)N=C(C(C)N=C(C(C)N)O)O)O

Synonyms:

• H-Ala-Ala-Phe-AMC
• alanylalanyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)phenylalaninamide
• Ala-Ala-Phe-Mca Hydrochloride

H-Ala-Ala-Phe-AMC (free base)

CAS: 62037-41-6

AAF-AMC, fluorogenic substrate for tripeptidyl peptidases I and II and for tripeptide aminopeptidase EC 3.4.11.4.

Formula: C₂₅H₂₈N₄O₅

Purity: > 99%

Color and Shape: White

Molecular weight: 464.52

Ref: 01-4002571

L-Alanyl-L-alanyl-L-phenylalanine 7-amido-4-methylcoumarin TFA Salt

Controlled Product

CAS: 62037-41-6

Applications L-Alanyl-L-alanyl-L-phenylalanine 7-amido-4-methylcoumarin is a peptide substrate for chymotrypsin and tripeptidyl peptidase II.

Formula: C₂₅H₂₈N₄O₅·C₂HF₃O₂

Color and Shape: Neat

Molecular weight: 578.53

Ref: TR-A511355

H-Ala-Ala-Phe-AMC

CAS: 62037-41-6

Fluorogenic substrate for protease

Formula: C₂₅H₂₈N₄O₅

Purity: Min. 99 Area-%

Color and Shape: White Powder

Molecular weight: 464.51 g/mol

Ref: 3D-FA49279

H-Ala-Ala-Phe-AMC

CAS: 62037-41-6

H-Ala-Ala-Phe-AMC is a positively charged peptide that binds to the extracellular domain of the human α2δ1 calcium channel. It is a research tool for studying the interactions between ligands and receptors, as well as protein interactions. H-Ala-Ala-Phe-AMC is used to study the pharmacology of ion channels, such as their activation and inhibition by different ligands. H-Ala-Ala-Phe-AMC can be used in cell biology studies to study protein interactions and changes in protein conformation.

Formula: C₂₅H₂₈N₄O₅

Purity: Min. 95%

Molecular weight: 464.51 g/mol

Ref: 3D-MCA-3201-V