CAS 622856-21-7

Formula: C24H19Cl2N3O3

InChI: InChI=1S/C24H19Cl2N3O3/c1-27-8-3-9-29-17-7-6-12(30)10-13(17)20-18(29)11-14(19-15(25)4-2-5-16(19)26)21-22(20)24(32)28-23(21)31/h2,4-7,10-11,27,30H,3,8-9H2,1H3,(H,28,31,32)

InChI key: WEIYKGMSZPBORY-UHFFFAOYSA-N

SMILES: CNCCCN1C2=C(C=C(C=C2)O)C3=C1C=C(C4=C3C(=O)NC4=O)C5=C(C=CC=C5Cl)Cl

PD-321852

CAS: 622856-21-7

PD-321852, a Chk1 inhibitor, boosts gemcitabine's effect in pancreatic cancer cells, varying from minimal in Panc1 to >30-fold in MiaPaCa2.

Formula: C₂₄H₁₉Cl₂N₃O₃

Color and Shape: Solid

Molecular weight: 468.33

Ref: TM-T68981