CAS 623152-17-0

BMS 582949

Description:

BMS 582949, with the CAS number 623152-17-0, is a chemical compound that has been studied primarily for its potential therapeutic applications, particularly in the field of oncology. It is classified as a small molecule inhibitor, specifically targeting certain pathways involved in cancer cell proliferation and survival. The compound exhibits selective inhibition of specific kinases, which are enzymes that play crucial roles in various cellular processes, including signal transduction and cell division. BMS 582949 has shown promise in preclinical studies, demonstrating efficacy against certain types of tumors. Its pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion, are essential for determining its suitability for clinical use. Additionally, safety and toxicity profiles are critical factors that researchers evaluate during the drug development process. Overall, BMS 582949 represents a significant area of interest in cancer research, with ongoing studies aimed at understanding its full potential and mechanisms of action.

Formula: C₂₂H₂₆N₆O₂

Synonyms:

• 4-[5-(cyclopropylcarbamoyl)-2-methylanilino]-5-methyl-N-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide
• CS-2900
• BMS 582949; BMS582949
• PS540446
• BMS 582949
• BMS582949(HCl)
• Pyrrolo[2,1-f][1,2,4]triazine-6-carboxamide, 4-[[5-[(cyclopropylamino)carbonyl]-2-methylphenyl]amino]-5-methyl-N-propyl-
• 4-[[5-[(Cyclopropylamino)carbonyl]-2-methylphenyl]amino]-5-methyl-N-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide

4-((5-(Cyclopropylcarbamoyl)-2-methylphenyl)amino)-5-methyl-N-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide

CAS: 623152-17-0

Formula: C₂₂H₂₆N₆O₂

Purity: 98%

Molecular weight: 406.4808

Ref: IN-DA00EIZX

BMS582949

CAS: 623152-17-0

BMS582949

Formula: C₂₂H₂₆N₆O₂

Purity: ≥95%

Molecular weight: 406.48

Ref: 54-BUP02708

Bms-582949

CAS: 623152-17-0

Bms-582949

Formula: C₂₂H₂₆N₆O₂

Purity: 98%

Color and Shape: Solid-Powder

Molecular weight: 406.48083

Ref: 54-BISN0294

BMS582949

CAS: 623152-17-0

BMS-582949 inhibits p38 MAPK with 13 nM IC50, blocking kinase activity and activation.

Formula: C₂₂H₂₆N₆O₂

Purity: 98.11%

Color and Shape: Solid

Molecular weight: 406.48

Ref: TM-T6789

BMS-582949

CAS: 623152-17-0

4-((5-(Cyclopropylcarbamoyl)-2-methylphenyl)amino)-5-methyl-N-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide

Formula: C₂₂H₂₆N₆O₂

Purity: 98%

Molecular weight: 406.48

Ref: IN-DG689149

BMS-582949

CAS: 623152-17-0

BMS-582949 is an investigational pharmaceutical compound, specifically a chemokine receptor antagonist, that has been derived through synthetic chemical processes. Its mode of action involves selectively inhibiting the C-C chemokine receptor type 2 (CCR2), a receptor involved in the migration and activation of monocytes and other immune cells. By blocking CCR2, BMS-582949 aims to modulate inflammatory pathways that are implicated in various diseases.

Formula: C₂₂H₂₆N₆O₂

Purity: Min. 95%

Molecular weight: 406.48 g/mol

Ref: 3D-YZA15217