CAS 624-49-7

Dimethyl fumarate

Description:

Dimethyl fumarate (DMF) is an organic compound with the molecular formula C6H8O4, classified as a fumarate ester. It appears as a white crystalline solid at room temperature and is known for its solubility in polar solvents such as water, methanol, and ethanol. DMF is characterized by its double bond between the carbon atoms in the fumarate moiety, which contributes to its reactivity and potential applications. It is primarily used in the pharmaceutical industry, notably as a treatment for multiple sclerosis, where it acts as an immunomodulator. Additionally, DMF has applications in the production of polymers and as a potential therapeutic agent in various inflammatory conditions. The compound is generally considered to have low toxicity, but it can cause skin irritation and other adverse effects upon exposure. Its stability under normal conditions makes it suitable for various formulations, although it should be handled with care to avoid degradation or unwanted reactions.

Formula: C₆H₈O₄

InChI: InChI=1S/C6H8O4/c1-9-5(7)3-4-6(8)10-2/h3-4H,1-2H3/b4-3+

InChI key: InChIKey=LDCRTTXIJACKKU-ONEGZZNKSA-N

SMILES: C(/C=C/C(OC)=O)(OC)=O

Synonyms:

• (2E)-2-Butenedioic acid dimethyl ester
• (E)-2-Butenedioic acid dimethyl ester
• (E)-But-2-enedioic acid dimethyl ester
• 2-Butenedioic acid (2E)-, 1,4-dimethyl ester
• 2-Butenedioic acid (2E)-, dimethyl ester
• 2-Butenedioic acid (E)-, dimethyl ester
• Allomaleic acid dimethyl ester
• Azl-O 211089
• Bg 00012
• Bg 12
• Boletic acid dimethyl ester
• Dimethyl (E)-2-butenedioate
• Dimethyl (E)-butenedioate
• Dimethyl trans-ethylenedicarboxylate
• Dimethylfumarat
• Dimethylfumarate
• Fumarate De Dimethyle
• Fumarate, Dimethyl
• Fumarato De Dimetilo
• Fumaric acid, dimethyl ester
• Fumarsaeure-Dimethylester
• Methyl fumarate
• Nsc 167432
• Nsc 25942
• Panaclar
• Skilarence
• Tecfidera
• Tecfira
• dimethyl (2E)-but-2-enedioate
• trans-1,2-Ethylenedicarboxylic acid dimethyl ester

Dimethyl Fumarate

CAS: 624-49-7

Formula: C₆H₈O₄

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 144.13

Ref: 3B-F0069

Dimethyl Fumarate

CAS: 624-49-7

Color and Shape: Neat

Ref: 61-FOR3170.00

Dimethyl Fumarate

CAS: 624-49-7

Acyclic polycarboxylic acids and their anhydrides, halides, peroxides and their derivatives, nesoi

Formula: C₆H₈O₄

Color and Shape: White Powder

Molecular weight: 144.04226

Ref: 45-1210218

(E)-Dimethyl fumarate

CAS: 624-49-7

Formula: C₆H₈O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 144.1253

Ref: IN-DA003PM2

Dimethyl fumarate

CAS: 624-49-7

Dimethyl fumarate

Purity: ≥90%

Molecular weight: 144.13g/mol

Ref: 54-BUP18658

Dimethyl Fumarate

CAS: 624-49-7

Formula: C₆H₈O₄

Color and Shape: White To Off-White Solid

Molecular weight: 144.13

Ref: 4Z-F-551

Dimethyl fumarate, min. 99%

CAS: 624-49-7

Formula: C₆H₈O₄

Purity: min. 99%

Color and Shape: White to off-white crystalline solid

Molecular weight: 144.12

Ref: 08-06-0040

Dimethyl Fumarate

Controlled Product

CAS: 624-49-7

Formula: C₆H₈O₄

Color and Shape: Neat

Molecular weight: 144.13

Ref: 86-MM3170.00

Fumaric acid-dimethyl ester

CAS: 624-49-7

Formula: C₆H₈O₄

Color and Shape: Neat

Molecular weight: 144.13

Ref: 04-C13955800

DIMETHYL FUMARATE

CAS: 624-49-7

Purity: 98%

Molecular weight: 144.126007080078

Ref: 10-F794923

Fumaric acid-dimethyl ester 1000 µg/mL in Acetonitrile

CAS: 624-49-7

Formula: C₆H₈O₄

Color and Shape: Colourless

Molecular weight: 144.13

Ref: 04-A13955800AL-1000

Dimethyl fumarate

CAS: 624-49-7

Dimethyl fumarate

Purity: 99%

Molecular weight: 144.13g/mol

Ref: 54-OR9602

Dimethyl fumarate

CAS: 624-49-7

Dimethyl fumarate (DMF) is an orally Nrf2 activator. Dimethyl fumarate has antimicrobial and anti-inflammatory activities. Cost-effective and quality-assured.

Formula: C₆H₈O₄

Purity: 90.51% - >99.99%

Color and Shape: White To Off-White Powder White Crystalline Powder

Molecular weight: 144.13

Ref: TM-T0492

Dimethyl fumarate

CAS: 624-49-7

Formula: C₆H₈O₄

Purity: ≥ 98.5% (anhydrous basis)

Color and Shape: White crystalline powder or crystals

Molecular weight: 144.13

Ref: 7W-GK0623

Dimethyl Fumarate

CAS: 624-49-7

Applications Dimethyl fumarate is the methyl ester form of Fumaric Acid (F500380), and is a compound used as a treatment for the relapsing forms of multiple sclerosis and psoriasis. Dimethyl fumarate is effective in treating multiple sclerosis by mediating the activation of the nuclear 1 factor (Nrf2) antioxidant response pathway, resulting in neuroprotective effects. Dimethyl fumarate is also used in cycloaddition reactions involving ylides, benzenes and amino acids.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Albrecht, P., et al.: J. Neuroinflammation, 9, 2094 (2012); Chen, X. et al.: J. Am. Chem. Soc., 130, 5652 (2008); Gold, R., et al.: New Engl. J Med., 367, 1098 (2012); Gothelf, A. et al.: Angew. Chem., Int. Ed., 41, 4236 (2002); Schmidt, T., et al.: Bioorg. Med. Chem., 15, 333 (2007)

Formula: C₆H₈O₄

Color and Shape: White

Molecular weight: 144.13

Ref: TR-D464965

Dimethyl fumarate

CAS: 624-49-7

Dimethyl fumarate (DMF) is a drug that acts as a prodrug for the active metabolite monomethyl fumarate (MMF). It is used in the treatment of psoriasis and other skin diseases, including erythema nodosum leprosum. DMF has been shown to significantly up-regulate the expression of proliferating cell nuclear antigen (PCNA), which is a response element for pdgf-bb. DMF also has antioxidant properties, which may be due to its ability to inhibit reactive oxygen species production. This drug also inhibits the activity of certain enzymes and blocks drug transporters that are involved in bowel disease.

Formula: C₆H₈O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 144.13 g/mol

Ref: 3D-FD15538

Dimethyl fumarate, 99%

CAS: 624-49-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₈O₄

Purity: 99%

Color and Shape: Crystals or crystalline powder or flakes, White to cream to pale brown

Molecular weight: 144.13

Ref: 02-A10402

Dimethyl fumarate

CAS: 624-49-7

Formula: C₆H₈O₄

Purity: 99.0 min. %

Color and Shape: White to off-white crystalline solid

Molecular weight: 144.12

Ref: 08-D033