CAS 624-49-7

Dimethyl fumarate

Description:

Dimethyl fumarate (DMF) is an organic compound with the molecular formula C6H8O4, classified as a fumarate ester. It appears as a white crystalline solid at room temperature and is known for its solubility in polar solvents such as water, methanol, and ethanol. DMF is characterized by its double bond between the carbon atoms in the fumarate moiety, which contributes to its reactivity and potential applications. It is primarily used in the pharmaceutical industry, notably as a treatment for multiple sclerosis, where it acts as an immunomodulator. Additionally, DMF has applications in the production of polymers and as a potential therapeutic agent in various inflammatory conditions. The compound is generally considered to have low toxicity, but it can cause skin irritation and other adverse effects upon exposure. Its stability under normal conditions makes it suitable for various formulations, although it should be handled with care to avoid degradation or unwanted reactions.

Formula:C₆H₈O₄

InChI:InChI=1S/C6H8O4/c1-9-5(7)3-4-6(8)10-2/h3-4H,1-2H3/b4-3+

InChI key:InChIKey=LDCRTTXIJACKKU-ONEGZZNKSA-N

SMILES:C(/C=C/C(OC)=O)(OC)=O

Synonyms:

(2E)-2-Butenedioic acid dimethyl ester
(E)-2-Butenedioic acid dimethyl ester
(E)-But-2-enedioic acid dimethyl ester
2-Butenedioic acid (2E)-, 1,4-dimethyl ester
2-Butenedioic acid (2E)-, dimethyl ester
2-Butenedioic acid (E)-, dimethyl ester
Allomaleic acid dimethyl ester
Azl-O 211089
Bg 00012
Bg 12
Boletic acid dimethyl ester
Dimethyl (E)-2-butenedioate
Dimethyl (E)-butenedioate
Dimethyl trans-ethylenedicarboxylate
Dimethylfumarat
Dimethylfumarate
Fumarate De Dimethyle
Fumarate, Dimethyl
Fumarato De Dimetilo
Fumaric acid, dimethyl ester
Fumarsaeure-Dimethylester
Methyl fumarate
Nsc 167432
Nsc 25942
Panaclar
Skilarence
Tecfidera
Tecfira
dimethyl (2E)-but-2-enedioate
trans-1,2-Ethylenedicarboxylic acid dimethyl ester
See more synonyms

Purity (%)

100

Found 18 products.

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Dimethyl Fumarate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 624-49-7
Formula:C₆H₈O₄
Purity:>98.0%(GC)
Color and Shape:White to Almost white powder to crystal
Molecular weight:144.13
Ref: 3B-F0069
25g
27.00€
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500g
145.00€
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Dimethyl fumarate, 99%
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 624-49-7
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci
Formula:C₆H₈O₄
Purity:99%
Color and Shape:Crystals or crystalline powder or flakes, White to cream to pale brown
Molecular weight:144.13
Ref: 02-A10402
25g
36.00€
VAT not included
100g
76.00€
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250g
140.00€
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Dimethyl Fumarate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 624-49-7
Acyclic polycarboxylic acids and their anhydrides, halides, peroxides and their derivatives, nesoi
Formula:C₆H₈O₄
Color and Shape:White Powder
Molecular weight:144.04226
Ref: 45-1210218
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(E)-Dimethyl fumarate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 624-49-7
Formula:C₆H₈O₄
Purity:98%
Color and Shape:Solid
Molecular weight:144.1253
Ref: IN-DA003PM2
10g
20.00€
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25g
20.00€
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100g
23.00€
VAT not included
200g
34.00€
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500g
40.00€
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1kg
62.00€
VAT not included
50kg
539.00€
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100kg
1,072.00€
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Dimethyl Fumarate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 624-49-7
Formula:C₆H₈O₄
Color and Shape:White To Off-White Solid
Molecular weight:144.13
Ref: 4Z-F-551
5mg
To inquire
100mg
To inquire
10mg
343.00€
VAT not included
25mg
436.00€
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50mg
623.00€
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Dimethyl fumarate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 624-49-7
Dimethyl fumarate
Formula:C₆H₈O₄
Purity:≥90%
Color and Shape:Solid
Molecular weight:144.13
Ref: 54-BUP18658
500mg
72.00€
VAT not included
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Dimethyl Fumarate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 624-49-7
Formula:C₆H₈O₄
Color and Shape:Neat
Molecular weight:144.13
Ref: 86-MM3170.00
250mg
1,135.00€
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Fumaric acid-dimethyl ester
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 624-49-7
Formula:C₆H₈O₄
Color and Shape:Neat
Molecular weight:144.13
Ref: 04-C13955800
250mg
54.00€
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Dimethyl Fumarate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 624-49-7
Color and Shape:Neat
Ref: 61-FOR3170.00
10mg
138.00€
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Fumaric acid-dimethyl ester 1000 µg/mL in Acetonitrile
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 624-49-7
Formula:C₆H₈O₄
Color and Shape:Single Solution
Molecular weight:144.13
Ref: 04-A13955800AL-1000
1ml
26.00€
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Dimethyl fumarate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 624-49-7
Dimethyl fumarate (DMF) is an orally Nrf2 activator. Dimethyl fumarate has antimicrobial and anti-inflammatory activities. Cost-effective and quality-assured.
Formula:C₆H₈O₄
Purity:90.51% - >99.99%
Color and Shape:White Solid
Molecular weight:144.13
Ref: TM-T0492
500mg
50.00€
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Dimethyl fumarate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 624-49-7
Formula:C₆H₈O₄
Purity:≥ 98.5% (anhydrous basis)
Color and Shape:White crystalline powder or crystals
Molecular weight:144.13
Ref: 7W-GK0623
500g
155.00€
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Dimethyl fumarate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 624-49-7
Dimethyl fumarate
Formula:C₆H₈O₄
Purity:99%
Color and Shape:Off-white Solid
Molecular weight:144.12532
Ref: 54-OR9602
500g
66.00€
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2500g
280.00€
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25kg
2,542.00€
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Dimethyl fumarate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 624-49-7
Dimethyl fumarate
Formula:C₆H₈O₄
Purity:99%
Molecular weight:144.13
Ref: IN-DG266354
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Dimethyl Fumarate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 624-49-7
Applications Dimethyl fumarate is the methyl ester form of Fumaric Acid (F500380), and is a compound used as a treatment for the relapsing forms of multiple sclerosis and psoriasis. Dimethyl fumarate is effective in treating multiple sclerosis by mediating the activation of the nuclear 1 factor (Nrf2) antioxidant response pathway, resulting in neuroprotective effects. Dimethyl fumarate is also used in cycloaddition reactions involving ylides, benzenes and amino acids.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Albrecht, P., et al.: J. Neuroinflammation, 9, 2094 (2012); Chen, X. et al.: J. Am. Chem. Soc., 130, 5652 (2008); Gold, R., et al.: New Engl. J Med., 367, 1098 (2012); Gothelf, A. et al.: Angew. Chem., Int. Ed., 41, 4236 (2002); Schmidt, T., et al.: Bioorg. Med. Chem., 15, 333 (2007)
Formula:C₆H₈O₄
Color and Shape:Neat
Molecular weight:144.13
Ref: TR-D464965
50mg
98.00€
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100mg
114.00€
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1g
167.00€
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Dimethyl fumarate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 624-49-7
Dimethyl fumarate (DMF) is a drug that acts as a prodrug for the active metabolite monomethyl fumarate (MMF). It is used in the treatment of psoriasis and other skin diseases, including erythema nodosum leprosum. DMF has been shown to significantly up-regulate the expression of proliferating cell nuclear antigen (PCNA), which is a response element for pdgf-bb. DMF also has antioxidant properties, which may be due to its ability to inhibit reactive oxygen species production. This drug also inhibits the activity of certain enzymes and blocks drug transporters that are involved in bowel disease.
Formula:C₆H₈O₄
Purity:Min. 95%
Color and Shape:Powder
Molecular weight:144.13 g/mol
Ref: 3D-FD15538
100g
229.00€
VAT not included
250g
376.00€
VAT not included
500g
478.00€
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1kg
815.00€
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2kg
1,323.00€
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Dimethyl fumarate, min. 99%
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 624-49-7
Formula:C₆H₈O₄
Purity:min. 99%
Color and Shape:White to off-white crystalline solid
Molecular weight:144.12
Ref: 08-06-0040
100g
172.00€
VAT not included
500g
664.00€
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DIMETHYL FUMARATE
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 624-49-7
Purity:98%
Molecular weight:144.13
Ref: 10-F794923
10g
17.00€
VAT not included
25g
17.00€
VAT not included
100g
18.00€
VAT not included
500g
43.00€
VAT not included
1kg
79.00€
VAT not included