CAS 624-67-9

Propynal

Description:

Propynal, also known as propyne-1-al or 2-propynal, is an organic compound characterized by its alkyne functional group and an aldehyde functional group. It has the molecular formula C3H4O, indicating it consists of three carbon atoms, four hydrogen atoms, and one oxygen atom. Propynal is a colorless liquid with a distinctive odor and is known for its reactivity due to the presence of both the triple bond in the alkyne and the carbonyl group in the aldehyde. It is soluble in organic solvents and can participate in various chemical reactions, including nucleophilic additions and polymerization. Propynal is primarily used in organic synthesis and as an intermediate in the production of other chemicals. Due to its reactive nature, it must be handled with care, as it can be flammable and potentially hazardous. Its applications extend to the fields of pharmaceuticals and agrochemicals, where it serves as a building block for more complex molecules.

Formula: C₃H₂O

InChI: InChI=1S/C3H2O/c1-2-3-4/h1,3H

InChI key: InChIKey=IJNJLGFTSIAHEA-UHFFFAOYSA-N

SMILES: C(C=O)#C

Synonyms:

• 2-Propyn-1-one
• 2-Propynal
• Acetylenecarboxaldehyde
• Brn 1098318
• Formylacetylene
• Prop-2-Ynal
• Propargylaldehyde
• Propioaldehyde
• Propiolaldehyde
• Propiolaldehye
• Propiolic aldehyde
• Propyn-3-al
• 4-01-00-03537 (Beilstein Handbook Reference)

Propynal

CAS: 624-67-9

Ref: 7W-GK9355

2-Propynal (>85%, stabilized with Hydroquinone)

Controlled Product

CAS: 624-67-9

Applications 2-Propynal is hypothesized to be a possible metabolite of pargyline, a monoamine oxidase inhibitor that is used as an antihypertensive agent. 2-Propynal is also known to induce hepatocyte toxicity in vivo in rats.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References DeMaster, E., et al.: Res. Comm. Chem. Pathol. Pharm., 21, 497 (1978); Langston, J., et al.: Science, 225, 1480 (1984); Moridani, M., et al.: Chem.-Biol. Interact, 130-132, 931 (2001)

Formula: C₃H₂O

Color and Shape: Neat

Molecular weight: 54.05

Ref: TR-P838440

Propynal, stabilised with Hydroquinone

CAS: 624-67-9

Propynal, stabilised with Hydroquinone is a drug that is used for the treatment of autoimmune diseases. It is an irreversible inhibitor of monoamine oxidase-A (MAO-A) and MAO-B and inhibits the activity of these enzymes in rat liver microsomes. Propynal, stabilised with Hydroquinone also inhibits mitochondrial membrane potential. The thermodynamic data show that propynal has a high affinity for hydroxyl groups. The reactivity of propynal is determined by the nucleophilic character of the hydroxyl group, which can be either electrophilic or nucleophilic in nature. The reaction mechanism involves a transfer reaction between methyl ethyl trifluoroacetate and propynol to form methyl ethyl trifluoroacetate hydroquinone oxime. This type of reaction is reversible and can be inhibited by pargyline.

Formula: C₃H₂O

Purity: (%) Min. 85%

Color and Shape: Clear Liquid

Molecular weight: 54.05 g/mol

Ref: 3D-FP13241